Background illustration for clinical trials search

Paid Clinical Trials Charlotte

Discover 646 paid clinical trials in Charlotte, North Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

Filter
2
FeaturedActive & Responsive

A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis

for
Rheumatoid Arthritis
Location: Charlotte NC, Summerville SC, Jacksonville FL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06972446

Phase 2, Recruiting
FeaturedActive & Responsive

A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Charlotte NC, Monroe NC, Greenville SC, Roanoke VA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819878

Phase 3, Recruiting
FeaturedActive & Responsive

Weight Loss Studies for Adults With a BMI of 27+, Including People Managing Type 2 Diabetes or Sleep Apnea

for
Obesity, Overweight, Diabetes Mellitus, Type 2,
Location: Monroe NC, Gaffney SC, Durham NC, New Bern NC,

Sex: All

Age: 18+

Recruiting
FeaturedActive & Responsive

Crohn's Disease and Ulcerative Colitis Studies for Adults With Hard-to-Treat Symptoms

for
Inflammatory Bowel Diseases, Crohn Disease, Colitis, Ulcerative
Location: Monroe NC, Ogden UT

Sex: All

Age: 18 - 70+

Recruiting
FeaturedActive & Responsive

High Blood Pressure Studies for Adults Whose Blood Pressure Stays High Despite Two or More Medications

for
Hypertension
Location: Monroe NC, Suffolk VA, Columbus GA, Cincinnati OH,

Sex: All

Age: 18+

Recruiting

Interested in new trials?

Get alerts for new trials in your area by subscribing now

Subscriber Image
FeaturedActive & Responsive

Cardiovascular Disease Studies for Adults With High Blood Pressure, High Cholesterol, AFib, or Heart Failure

for
Cardiovascular Diseases, Heart Failure, Atrial Fibrillation,
Location: Monroe NC, Gaffney SC, Union SC, Mauldin SC, Durham NC,

Sex: All

Age: 18+

Recruiting
FeaturedActive & Responsive

Type 2 Diabetes Studies on Blood Sugar and Weight Management for Adults Not on Insulin

for
Diabetes Mellitus, Type 2, Obesity
Location: Gaffney SC, Anderson SC, Durham NC, Charleston SC,

Sex: All

Age: 18 - 70+

Recruiting
FeaturedActive & Responsive

COPD, Emphysema, and Chronic Bronchitis Studies for Current or Former Smokers

for
Pulmonary Disease, Chronic Obstructive
Location: Gaffney SC, Union SC, Spartanburg SC, Columbia SC,

Sex: All

Age: 40 - 70+

Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: Charlotte NC, Winston-Salem NC, Atlanta GA, Norfolk VA,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase 1, Phase 2, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for
Breast Cancer
Location: Charlotte NC, Winston-Salem NC, Greenville SC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06790693

Phase 3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: Charlotte NC, High Point NC, Atlanta GA, Richmond VA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase 3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

for
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer,
Location: Charlotte NC, Philadelphia PA, Germantown TN, Boston MA,
Sponsor: Hoffmann-La Roche

Sex: Female

Age: 18+

Code: NCT04802759

Phase 1, Phase 2, Recruiting
Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: Charlotte NC, Winston-Salem NC, Chapel Hill NC,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase 2, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

for
Multiple Myeloma
Location: Charlotte NC, Winston-Salem NC, Hillsborough NC,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06953960

Phase 1, Phase 2, Recruiting
Featured

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

for
Multiple Myeloma
Location: Charlotte NC, Winston-Salem NC, Chapel Hill NC,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06892522

Phase 1, Phase 2, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

for
Metastatic Breast Cancer
Location: Charlotte NC, Washington D.C. DC, Hyattsville MD,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT05894239

Phase 3, Recruiting
Featured

Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for
Multiple Myeloma
Location: Charlotte NC, Winston-Salem NC, Atlanta GA,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT07555938

Phase 3, Recruiting
Featured

Study to Assess Adverse Events and Disease Activity of Oral Ubrogepant Tablets for the Acute Treatment of Migraine in Children and Adolescents (Ages 6-17)

for
Migraine
Location: Charlotte NC, Greenville SC, Atlanta GA, Savannah GA,
Sponsor: AbbVie

Sex: All

Age: 6 - 17

Code: NCT05125302

Phase 3, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis,
Location: Charlotte NC, Winston-Salem NC, Columbia SC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18 - 70+

Code: NCT06318169

Phase 3, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for
Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis,
Location: Charlotte NC, Winston-Salem NC, Columbia SC,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18 - 70+

Code: NCT06419374

Phase 3, Recruiting