Discover 2,978 paid clinical trials in Massachusetts. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.
Sponsor:
Brigham and Women's Hospital
Location:
Code:
NCT04880265
Conditions
Atrial Fibrillation
Cardiac Surgery
Eligibility Criteria
Sex: All
Age: 20 - 70+
Healthy Volunteers: Not accepted
Interventions
BraveHeart wearable life sensors
Sponsor:
Gilead Sciences
Location:
Code:
NCT06060665
Conditions
Primary Biliary Cholangitis
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Seladelpar 10 mg
Placebo
Sponsor:
Children's Oncology Group
Location:
Code:
NCT05235165
Conditions
Metastatic Malignant Neoplasm in the Lung
Metastatic Osteosarcoma
Osteosarcoma
Eligibility Criteria
Sex: All
Age: 0 - 50
Healthy Volunteers: Not accepted
Interventions
Biospecimen Collection
Computed Tomography
Questionnaire Administration
Thoracoscopy
Thoracotomy
Sponsor:
Massachusetts General Hospital
Location:
Code:
NCT04842266
Conditions
Cancer Metastatic
Trauma
Pathologic Fracture
Eligibility Criteria
Sex: All
Age: 21+
Healthy Volunteers: Not accepted
Interventions
IlluminOss pelvic implant for oncologic indication
IlluminOss pelvic implant for geriatric trauma indication
Sponsor:
Sanofi
Location:
Code:
NCT06130566
Conditions
Dermatitis Atopic
Eligibility Criteria
Sex: All
Age: 12+
Healthy Volunteers: Not accepted
Interventions
Amlitelimab
Placebo
Sponsor:
University of British Columbia
Location:
Code:
NCT04812366
Conditions
Prostate Cancer
Eligibility Criteria
Sex: Male
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Apalutamide 60mg Tab
Abiraterone Acetate 250mg
Prednisone 5mg Tab
Docetaxel
Niraparib 100mg Oral Capsule
Sponsor:
Boston Children's Hospital
Location:
Code:
NCT05899166
Conditions
Diabetes Mellitus, Type 1
Eligibility Criteria
Sex: All
Age: 5 - 12
Healthy Volunteers: Not accepted
Interventions
Ketogenic diet, food delivery and education
Standard diet, food delivery and education
Sponsor:
Alkeus Pharmaceuticals, Inc.
Location:
Code:
NCT02402660
Conditions
Stargardt Disease
Stargardt Macular Degeneration
Stargardt Macular Dystrophy
Autosomal Recessive Stargardt Disease 1 (ABCA4-related)
Eligibility Criteria
Sex: All
Age: 8 - 70
Healthy Volunteers: Not accepted
Interventions
ALK-001
Placebo
Sponsor:
Incyte Corporation
Location:
Code:
NCT06548360
Conditions
NonSegmental Vitiligo
Eligibility Criteria
Sex: All
Age: 2 - 11
Healthy Volunteers: Not accepted
Interventions
Ruxolitinib Cream
Vehicle Cream
Sponsor:
Boston University
Location:
Code:
NCT04468360
Conditions
Post Traumatic Stress Disorder
Eligibility Criteria
Sex: All
Age: 18 - 55
Healthy Volunteers: Not accepted
Interventions
3-day differential fear conditioning, extinction, and extinction retention testing paradigm
Allopregnanolone (Allo) with Dexolve in 0.9% saline for injection manufactured by University of California, Davis
Matching IV Placebo
With its extensive healthcare network and prestigious research institutions, Massachusetts is a prime destination for a diverse array of clinical trials. Renowned centers such as Massachusetts General Hospital, Brigham and Women's Hospital, the Dana-Farber Cancer Institute, and Moderna are at the forefront of these studies.
These institutions are leading the way in advancing medical research and innovation, contributing significantly to the development of new treatments and therapies for both those living in Massachusetts and the wider population.
Massachusetts stands out as a premier location for clinical trials due to its world-class healthcare institutions and robust research ecosystem. These institutions not only offer access to groundbreaking treatments and therapies but also provide participants with exceptional care and close monitoring from top-tier healthcare professionals.
In addition to high-quality clinical care, participating in trials in Massachusetts allows individuals to contribute to groundbreaking research that can lead to significant medical advancements. The state’s vibrant research environment, supported by major universities and a strong biotech industry, ensures that participants are involved in studies that push the boundaries of current medical knowledge.
Massachusetts’ extensive research infrastructure supports a wide range of studies aimed at advancing treatments and improving patient outcomes across several conditions.
Clinical trials in Massachusetts focus on several autoimmune diseases, including rheumatoid arthritis, lupus, and multiple sclerosis (MS). Researchers here explore innovative treatments and seek to advance our understanding of these complex diseases. Trials often investigate novel biologics and small molecule drugs designed to target specific immune pathways and reduce inflammation more effectively.
Trials may also use biomarkers and imaging technologies to better understand disease mechanisms and patient responses to treatment. The state’s strong research infrastructure, combined with access to a diverse patient population, provides an ideal environment for pioneering studies that drive progress in autoimmune disease management and treatment.
Clinical trials for metabolic disorders in Massachusetts focus on exploring new and innovative treatments for a variety of complex conditions. Current trials investigate novel therapies for disorders such as type 1 and type 2 diabetes, obesity, phenylketonuria (PKU), and rare inherited metabolic diseases like Gaucher disease and Pompe disease.
Research includes testing new drug formulations, advanced insulin delivery systems, and gene therapies aimed at correcting underlying metabolic deficiencies. Trials also explore dietary interventions and enzyme replacement therapies to help manage these conditions and improve patient outcomes. Given the complexity of metabolic disorders and their significant impact on quality of life and overall health, these trials are crucial for developing more effective treatment options.
With a high number of infectious diseases reported in Massachusetts every year, clinical trials for these conditions have gained prevalence. Clinical trials for infectious diseases in Massachusetts investigate a range of innovative treatments and preventive measures aimed at combating both emerging and established pathogens.
Current trials include studies on novel vaccines for diseases such as COVID-19, influenza, and tuberculosis, exploring new formulations and delivery methods to enhance efficacy and safety. Research also focuses on developing new antiviral and antimicrobial drugs to tackle resistant strains of bacteria and viruses, including trials for treatments targeting HIV/AIDS and hepatitis C. Additionally, trials are evaluating new therapeutic approaches, such as monoclonal antibodies and immune modulators, to improve outcomes for patients with severe infectious diseases.
In Massachusetts, cancer clinical trials cover a diverse array of innovative approaches and methodologies, reflecting the state’s leadership in oncology research. Trials are investigating innovative cancer treatments such as immunotherapy, which harnesses the body's immune system to target cancer cells more effectively. These studies explore new checkpoint inhibitors, CAR-T cell therapies, and combination therapies that aim to enhance immune responses against various cancers, including lung, breast, prostate, and leukemia.
Additionally, research includes targeted therapies that focus on specific genetic mutations within cancer cells, offering more precise treatment options with potentially fewer side effects. Studies are also examining novel drug combinations, advanced radiation techniques, and emerging therapies like gene editing and personalized vaccines.
Interested in learning more about how clinical trials for cancer work? Explore our guide to better understand oncology clinical trials and how they contribute to advancing cancer treatments.
Cardiovascular disease trials in Massachusetts are exploring a range of innovative approaches aimed at improving treatment outcomes and patient care. With heart disease being one of the leading causes of death in the state, researchers have placed a strong emphasis on learning more about cardiovascular conditions in order to seek new treatment options and preventative measures.
Research includes studies on advanced medications, groundbreaking technologies, and regenerative medicine techniques, such as stem cell therapies, to repair damaged heart tissue and improve cardiac function.
In Massachusetts, clinical trials for mental health conditions are exploring a wide range of innovative treatments and therapies aimed at improving outcomes for individuals with various mental health disorders.
Current research includes trials on novel antidepressants and anxiolytics, investigating new mechanisms of action and targeted treatments for conditions such as depression, anxiety disorders, PTSD, and bipolar disorder. Additionally, studies are examining the potential of psychedelic compounds and ketamine for treatment-resistant depression, as well as exploring advanced psychotherapies and digital mental health tools designed to enhance therapeutic efficacy and accessibility.
In Massachusetts, neurological disorder studies are aimed at developing new treatments and advancing our understanding of complex neurological conditions. Current trials focus on a variety of disorders including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis (MS), and amyotrophic lateral sclerosis (ALS).
Research includes studies on novel drug therapies aimed at modifying disease progression, enhancing cognitive function, and improving motor skills. Trials are also exploring innovative approaches such as gene therapy, stem cell therapy, and advanced neurostimulation techniques to target underlying disease mechanisms and provide new therapeutic options.
In Massachusetts, clinical trials are governed by a combination of federal and state regulations that ensure the safety, ethics, and scientific integrity of research. Federally, trials adhere to guidelines set by the U.S. Food and Drug Administration (FDA) and the Office for Human Research Protections (OHRP), which oversee study protocols, informed consent processes, and the protection of human subjects.
At state level, Massachusetts follows these federal guidelines alongside its own regulatory framework through agencies such as the Massachusetts Department of Public Health and the Massachusetts Medical Device Industry Council. Local Institutional Review Boards (IRBs) are responsible for reviewing and approving research proposals to ensure compliance with ethical standards and participant protections.
Additionally, Massachusetts requires adherence to state-specific laws concerning informed consent and data privacy, ensuring all clinical research meets both federal and state requirements for ethical conduct and participant safety.
Joining a clinical trial provides numerous advantages for participants, such as gaining access to the latest treatments and therapies that are not yet widely available. Participants benefit from comprehensive care provided by leading healthcare professionals, who offer specialized monitoring and support throughout the study.
Moreover, participating in clinical trials contributes to critical medical research, which can lead to major breakthroughs in treatment. By taking part, individuals not only receive early access to cutting-edge medical interventions but also help advance scientific knowledge, ultimately improving healthcare outcomes for future patients.
Enrolling in a clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started: