IVF Clinical Trials
Find clinical trials for ivf. Search for ivf clinical trials in different cities and states across the United States.
Effect of Testosterone Treatment on Embryo Quality
Sponsor:
Center for Human Reproduction
Location:
Code:
NCT01662466
Conditions
Primary Ovarian Insufficiency
Female Infertility Due to Diminished Ovarian Reserve
Eligibility Criteria
Sex: Female
Age: 38 - 44
Healthy Volunteers: Not accepted
Interventions
Testosterone cream (0.5mg per gram)
DHEA
Placebo
The LUTEAL Trial: Luteal Stimulation vs. Estrogen Priming Protocol
Sponsor:
Northwell Health
Location:
Code:
NCT04447872
Conditions
Infertility
Diminished Ovarian Reserve
IVF
Eligibility Criteria
Sex: Female
Age: 20 - 45
Healthy Volunteers: Not accepted
Interventions
Timing of injectable gonadotropins
Endometrial Biopsy Prior to IVF in Those Patients With Prior Implantation Failure
Sponsor:
Shady Grove Fertility Reproductive Science Center
Location:
Code:
NCT01800513
Conditions
Implantation Failure
Infertility
Eligibility Criteria
Sex: Female
Age: 18 - 37
Healthy Volunteers: Not accepted
Interventions
Endometrial Biopsy
Sham Procedure
Experimental Round Spermatid Injection (ROSI) to Treat Infertile Couples
Sponsor:
Wake Forest University Health Sciences
Location:
Code:
NCT04298255
Conditions
Infertility, Male
Eligibility Criteria
Sex: Male
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Round Spermatid Injection (ROSI)
Half ROSI-half Sperm Donor Fertilization
What are IVF clinical trials?
IVF (In Vitro Fertilization) clinical trials are research studies that explore innovative approaches to improve IVF outcomes, address infertility issues, and enhance assisted reproductive technologies (ART). These trials may investigate new medications, procedures, or technologies designed to increase the success rates of IVF treatments, understand the underlying causes of infertility, and develop more effective and patient-friendly fertility treatments.
Importance of clinical trials for IVF
Clinical trials for IVF play a crucial role in advancing reproductive medicine by testing the safety and effectiveness of new treatments and interventions. They offer hope to couples struggling with infertility by potentially providing access to the latest advancements in IVF technology and protocols. These studies help to refine IVF procedures, improve embryo implantation rates, and increase the overall success rates of achieving pregnancies.
Types of interventions studied in IVF clinical trials
In vitro fertilization (IVF) clinical trials investigate various interventions aimed at improving the success rates and outcomes of IVF treatment. These interventions may target different stages of the IVF process or address specific challenges faced by individuals undergoing fertility treatment. Some common types of interventions studied in IVF clinical trials are:
Novel drug therapies
Studies may assess the efficacy of new pharmacological treatments, such as the use of GnRH (Gonadotropin-Releasing Hormone) antagonists in women with endometriosis undergoing IVF, to improve fertility outcomes.
Ovarian Stimulation
Trials may compare different protocols for ovarian stimulation, which involves the administration of fertility medications to stimulate the ovaries to produce multiple eggs. These protocols may vary in terms of the type, dosage, timing, and duration of medication administration, as well as the use of alternative stimulation protocols such as natural cycle IVF or minimal stimulation IVF.
Genetic screening and testing
Clinical trials may assess the use of genetic screening and testing techniques to identify chromosomal abnormalities, genetic mutations, or other genetic factors that may impact embryo viability and implantation. This includes testing embryos for aneuploidy using preimplantation genetic testing for aneuploidy (PGT-A) or screening for monogenic disorders using preimplantation genetic testing for monogenic/single gene disorders (PGT-M).
Advanced IVF techniques
Clinical trials may evaluate different culture media, incubation conditions, and laboratory techniques for culturing embryos in the IVF laboratory. This includes exploring the use of time-lapse imaging systems, embryo monitoring technologies, and embryo selection algorithms to improve embryo quality and selection. Research includes evaluating innovative IVF procedures or auxiliary techniques aimed at enhancing egg retrieval, embryo development, and implantation processes.
Assistive reproductive technologies (ART)
Trials may investigate the efficacy and safety of adjunctive ART techniques used in conjunction with IVF, such as intracytoplasmic sperm injection (ICSI), assisted hatching, embryo biopsy for preimplantation genetic testing (PGT), and embryo cryopreservation (freezing) for future use.
Lifestyle factors and psychological support
Some trials may explore the impact of lifestyle factors, environmental exposures, and behavioral interventions on IVF outcomes. This includes studying the effects of diet, exercise, smoking cessation, stress reduction, and environmental toxins on fertility and reproductive health.
While others investigate the role of psychosocial support interventions, counseling programs, and educational resources in improving the emotional well-being and coping strategies of individuals undergoing IVF treatment.
Eligibility and participation in IVF clinical trials
Eligibility for IVF clinical trials typically focuses on individuals or couples experiencing infertility. Specific criteria may include age, fertility history, and specific infertility diagnoses, such as endometriosis. Trials might be open to healthy volunteers for certain studies focusing on new technologies or procedures that do not require the participants to have fertility issues.
What to expect when participating in an IVF clinical trial
Participants in IVF clinical trials can expect to undergo an extensive screening process to determine eligibility, receive detailed information about the study's purpose, and follow the trial protocol under close medical supervision. This may involve taking new medications, undergoing specialized IVF procedures, and participating in follow-up evaluations to assess the outcomes of the treatment.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
How to enroll in an IVF clinical trial
Enrolling in an IVF clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify Your Trial: Use our search tool or filters to find IVF clinical trials that match your specific fertility needs or interests. This step simplifies the process of finding relevant research studies tailored to your requirements.
- Select Your Preferred Location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.