Multiple Sclerosis Clinical Trials
Find clinical trials for multiple sclerosis. Search for multiple sclerosis clinical trials in different cities and states across the United States.
First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)
Sponsor:
Regeneron Pharmaceuticals
Location:
Code:
NCT06351592
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Mutation in the Superoxide Dismutase-1 (SOD1) Gene
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
ALN-SOD
Diluent
Placebo (PB)
Autoimmune Intervention Mastery Course StudyAutoimmune Intervention Mastery Course Study
Sponsor:
Terry L. Wahls
Location:
Code:
NCT05057676
Conditions
Multiple Sclerosis
Clinically Isolated Syndrome
Fibromyalgia
Post Acute Sequelae of COVID-19
Cancer in Remission With Persisting Fatigue
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Immediate Autoimmune Intervention Mastery Course (AIM)
Immediate Question and Answer sessions. (AIM Q and A sessions)
Delayed Autoimmune Intervention Mastery Course (delayed AIM course)
Delayed AIM Question and Answer sessions
A Therapeutic Experience Program (TEP) Study for Improvement of Gait in People With Multiple Sclerosis (MS)A Therapeutic Experience Program (TEP) Study for Improvement of Gait in People With Multiple Sclerosis (MS)
Sponsor:
Helius Medical Inc
Location:
Code:
NCT05437276
Conditions
Gait Impairment Due to Mild/Moderate Multiple Sclerosis (MS)
Eligibility Criteria
Sex: All
Age: 22 - 65
Healthy Volunteers: Not accepted
Interventions
PoNS®
Reinventing Yourself With Multiple Sclerosis (MS)Reinventing Yourself With Multiple Sclerosis (MS)
Sponsor:
Kessler Foundation
Location:
Code:
NCT05195320
Conditions
Multiple Sclerosis
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Reinvention with MS
Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)
Sponsor:
Novartis Pharmaceuticals
Location:
Code:
NCT05147220
Conditions
Relapsing Multiple Sclerosis
Eligibility Criteria
Sex: All
Age: 18 - 55
Healthy Volunteers: Not accepted
Interventions
Remibrutinib
Teriflunomide
9-month Study to Assess the Efficacy of Ofatumumab on Microglia in Patients With Relapsing Forms of Multiple Sclerosis9-month Study to Assess the Efficacy of Ofatumumab on Microglia in Patients With Relapsing Forms of Multiple Sclerosis
Sponsor:
Brigham and Women's Hospital
Location:
Code:
NCT04510220
Conditions
Relapsing Multiple Sclerosis
Eligibility Criteria
Sex: All
Age: 18 - 60
Healthy Volunteers: Not accepted
Interventions
Ofatumumab
[F-18]PBR06
User-friendliness of a Portable Driving SimulatorUser-friendliness of a Portable Driving Simulator
Sponsor:
University of Kansas Medical Center
Location:
Code:
NCT03969927
Conditions
Parkinson Disease
Multiple Sclerosis
Stroke
Eligibility Criteria
Sex: All
Age: 25 - 70+
Healthy Volunteers: Not accepted
Interventions
Low-Fidelity PDS
High Fidelity Fixed-Base Simulator
Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)
Sponsor:
Kessler Foundation
Location:
Code:
NCT06191380
Conditions
Multiple Sclerosis
Eligibility Criteria
Sex: All
Age: 18 - 70
Healthy Volunteers: Not accepted
Interventions
PACE-MS
Study of the Disease Process of LymphangioleiomyomatosisStudy of the Disease Process of Lymphangioleiomyomatosis
Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Location:
Code:
NCT00001465
Conditions
Lung Disease
Pneumothorax
Tuberous Sclerosis
Lymphangioleiomyomatosis
Eligibility Criteria
Sex: All
Age: 16 - 70+
Healthy Volunteers: Not accepted
Interventions
Toshibia Aquilion One CT
AMX0114 in Adult Participants With Amyotrophic Lateral SclerosisAMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
Sponsor:
Amylyx Pharmaceuticals Inc.
Location:
Code:
NCT06665165
Conditions
ALS
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
AMX0114
Placebo
What are multiple sclerosis (MS) clinical trials?
Multiple sclerosis (MS) clinical trials are research studies that test new ways to treat, manage, or prevent MS. These trials are essential for developing new medications, therapies, and strategies to improve the quality of life for individuals living with MS. They range from early-stage research, testing the safety and efficacy of new treatments, to later-stage trials that compare new treatments to current standards.
The importance of clinical trials in MS research
Clinical trials are fundamental to MS research as they provide the scientific basis for developing new treatments and understanding the disease better. Through these trials, researchers can evaluate the effectiveness of new drugs, therapies, and management strategies, ensuring that only the most effective treatments are approved for general use. Clinical trials also help in identifying the causes of MS and factors that influence disease progression.
Types of multiple sclerosis clinical trials
Multiple sclerosis (MS) clinical trials encompass a range of studies, each targeting different aspects of this neurological condition. They range from exploring new medications and therapies aimed at managing symptoms and altering the disease's course, to prevention strategies and rehabilitation methods to enhance the quality of life for those affected.
Treatment trials
Treatment trials in MS focus on finding new medications or treatment strategies to manage the symptoms of MS. These include trials for drugs that can effectively manage symptoms of MS, reduce the frequency and severity of relapses, and slow the progression of the disease.
Prevention trials to delay or prevent MS progression
Prevention trials aim to identify strategies that could prevent MS or delay its progression in individuals who are at high risk or in the early stages of the disease. These studies might involve lifestyle changes, medications, or other interventions that could potentially prevent the onset or reduce the progression of MS.
Rehabilitation trials
Rehabilitation trials research ways to improve daily functioning and quality of life for those diagnosed with MS. These trials might test physical therapy programs, cognitive rehabilitation techniques, or novel assistive technologies designed to help manage the symptoms of MS.
Trials for emerging therapies
These trials explore the potential of new and emerging therapies in MS treatment, such as stem cell therapy, neuroprotective strategies, and novel immunotherapies. The goal is to find breakthrough treatments that can significantly alter the course of MS.
Who can participate in MS clinical trials?
Eligibility for MS clinical trials varies depending on the study's focus. Generally, these trials are open to individuals who have been diagnosed with MS, though specific criteria like the type of MS, the stage of the disease, and overall health will vary. Some trials may also be open to healthy volunteers without MS for preventative studies.
What to expect when joining an MS clinical trial
When joining an MS clinical trial, participants can expect to go through a detailed consent process, where they will be informed about the purpose of the study, the procedures involved, potential risks and benefits, and their rights as participants. Participants will undergo initial evaluations and be closely monitored throughout the study for any changes in their condition. Regular follow-ups and assessments are usually part of the process to ensure the effectiveness of the treatment being studied.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
How to enroll in a clinical trial for multiple sclerosis
Enrolling in an MS clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify Your Trial: Use our intuitive search bar or filter options to locate clinical trials specific to requirements. This first step simplifies the process of finding relevant research studies tailored to your needs.
- Select Your Preferred Location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.