Arthritis Clinical Trials
Find clinical trials for arthritis. Search for arthritis clinical trials in different cities and states across the United States.
PRP for Glenohumeral OsteoarthritisPRP for Glenohumeral Osteoarthritis
Sponsor:
Hospital for Special Surgery, New York
Location:
Code:
NCT05675527
Conditions
Shoulder Osteoarthritis
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Low-dose PRP
High-dose PRP
Saline
Intra-Operative Adductor Canal BlocksIntra-Operative Adductor Canal Blocks
Sponsor:
Ottawa Hospital Research Institute
Location:
Code:
NCT05601427
Conditions
Knee Osteoarthritis
Knee Arthritis
Knee Pain Chronic
Anesthesia
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
aACB
sACB
Corticosteroid Injection Versus Nerve BlockCorticosteroid Injection Versus Nerve Block
Sponsor:
University of Minnesota
Location:
Code:
NCT06735027
Conditions
Glenohumeral Arthritis
Rotator Cuff Arthropathy
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
intraarticular corticosteroid injection (IACI)
suprascapular nerve block (SSNB)
Exercise Plus Duloxetine for Knee OsteoarthritisExercise Plus Duloxetine for Knee Osteoarthritis
Sponsor:
University of Maryland, Baltimore
Location:
Code:
NCT04111627
Conditions
Knee Osteoarthritis
Depression
Eligibility Criteria
Sex: All
Age: 40+
Healthy Volunteers: Not accepted
Interventions
Aerobic exercise
Duloxetine
Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid ArthritisStudy to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis
Sponsor:
AbbVie
Location:
Code:
NCT05814627
Conditions
Rheumatoid Arthritis
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Upadacitinib
Adalimumab
Upadacitinib Matching Placebo
Adalimumab Matching Placebo
Hip Arthroscopy Versus Total Hip Arthroplasty RCTHip Arthroscopy Versus Total Hip Arthroplasty RCT
Sponsor:
Western University, Canada
Location:
Code:
NCT04166227
Conditions
Hip Osteoarthritis
Eligibility Criteria
Sex: All
Age: 40 - 60
Healthy Volunteers: Not accepted
Interventions
Hip Arthroscopy
Total Hip Arthroplasty
Effectiveness of the Journey Total Knee Arthroplasty Versus Two Standard of Care Total Knee Arthroplasty ProsthesesEffectiveness of the Journey Total Knee Arthroplasty Versus Two Standard of Care Total Knee Arthroplasty Prostheses
Sponsor:
University of Alberta
Location:
Code:
NCT03895489
Conditions
Osteoarthritis, Knee
Eligibility Criteria
Sex: All
Age: 50 - 70+
Healthy Volunteers: Not accepted
Interventions
Journey II
Stryker
Zimmer
Fitness Integrative Training for Pediatric Rheumatology DisordersFitness Integrative Training for Pediatric Rheumatology Disorders
Sponsor:
Children's Hospital Medical Center, Cincinnati
Location:
Code:
NCT06556992
Conditions
Juvenile Idiopathic Arthritis
Systemic Lupus Erythematosus of Childhood
Joint Hypermobility
Juvenile Dermatomyositis
Eligibility Criteria
Sex: All
Age: 10 - 19
Healthy Volunteers: Not accepted
Interventions
FIT Teens
Comparing Local Anesthesia With and Without iPACK BlockComparing Local Anesthesia With and Without iPACK Block
Sponsor:
University of Calgary
Location:
Code:
NCT04635176
Conditions
Osteo Arthritis Knee
Analgesia
Pain, Postoperative
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Real iPACK block (20 mL of 0.25% bupivacaine, 2.5mcg/mL epinephrine, and 50mcg/mL preservative-free dexamethasone)
Sham iPACK block with 20ml normal saline
What are arthritis clinical trials?
Arthritis clinical trials are research studies aimed at finding new treatments, understanding disease mechanisms, and improving the quality of life for individuals with arthritis. These trials test the safety and efficacy of innovative treatments, including medications, lifestyle interventions, and surgical procedures, to determine their potential benefits for patients with various forms of arthritis.
The importance of clinical trials in arthritis research
Clinical trials play a pivotal role in advancing arthritis research, offering hope for new treatments and insights into managing the disease more effectively. They are crucial for developing medications that can reduce pain, improve mobility, and slow disease progression. By participating in clinical trials, individuals contribute to knowledge that could lead to breakthroughs in arthritis care.
Types of arthritis clinical trials
Arthritis clinical trials encompass a wide range of studies aimed at understanding and treating the various forms of arthritis, each with its own set of challenges and treatment needs.
Trials focused on rheumatoid arthritis
These trials investigate treatments specifically for rheumatoid arthritis, an autoimmune condition that causes inflammation and joint damage. Studies often explore new medications, biologics that target specific pathways in the immune response, and strategies to manage symptoms, prevent joint damage and maintain joint function.
Trials for osteoarthritis
Osteoarthritis trials focus on the most common form of arthritis, characterized by the breakdown of cartilage in joints. Studies often explore pain management options, ways to slow cartilage degradation, and methods to improve joint function and quality of life for those affected by this condition.
Studies on juvenile arthritis
These trials are dedicated to children and adolescents with arthritis, aiming to find effective and safe treatments that can manage symptoms without affecting growth and development. They often include medications, physical therapies, and educational interventions to support the child and their family.
Trials for autoimmune arthritis variants
These trials cover other forms of autoimmune arthritis, such as psoriatic arthritis, exploring treatments that address both joint issues and skin manifestations of the disease. They aim to find therapies that can target the autoimmune aspects of these conditions effectively.
Innovations in arthritis treatment through clinical trials
The landscape of arthritis treatment is continuously evolving, with clinical trials bringing forth new and innovative approaches. Some of these approaches include new pharmacological treatments, personalized treatment approaches and non-pharmacological interventions and lifestyle changes among others.
New pharmacological treatments and biologics
Clinical trials are continually testing new drugs and biologic treatments that target specific pathways involved in arthritis. These innovations aim to offer more effective pain management with fewer side effects than traditional therapies.
Non-pharmacological interventions and lifestyle changes
Studies in this area explore the impact of diet, exercise, and other lifestyle modifications on arthritis symptoms and disease progression. They seek to understand how non-drug approaches can complement traditional treatments to improve patient outcomes.
Surgical interventions and advanced therapeutics
Advancements in surgical techniques and the exploration of regenerative medicine, including stem cell therapy and tissue engineering, are being tested for their potential to restore function in severely affected joints.
Precision medicine and personalized treatment approaches
Arthritis clinical trials are increasingly focusing on precision medicine - tailoring treatments to individual patient characteristics, such as genetic makeup, to optimize efficacy and minimize adverse effects. This approach aims to provide more personalized and effective treatment strategies by considering the unique aspects of each patient's condition.
Who can participate in arthritis clinical trials?
Individuals diagnosed with various forms of arthritis may be eligible to participate in clinical trials. Eligibility criteria vary by study and can include factors like age, disease severity, and previous treatment history. Trials may be designed for newly diagnosed patients, those with specific forms of arthritis, or individuals for whom standard treatments have not been effective.
What to expect in an arthritis clinical trial
Participants in arthritis clinical trials can expect a thorough screening process, informed consent, and detailed information about the trial's purpose and procedures. During the trial, participants receive the study treatment under close monitoring and undergo regular assessments to track their progress and any side effects.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
How to enroll in an arthritis clinical trial
Enrolling in a clinical trial for arthritis through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify Your Trial: Use our intuitive search bar or filter options to locate clinical trials specific to requirements. This first step simplifies the process of finding relevant research studies tailored to your needs.
- Select Your Preferred Location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.