Vaccines Clinical Trials
Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.
Intralesional Influenza Vaccine for the Treatment of Stage I-IV MelanomaIntralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma
Sponsor:
Carlo Contreras
Location:
Code:
NCT04697576
Conditions
Clinical Stage I Cutaneous Melanoma AJCC V8
Clinical Stage IA Cutaneous Melanoma AJCC V8
Clinical Stage IB Cutaneous Melanoma AJCC V8
Clinical Stage II Cutaneous Melanoma AJCC V8
Clinical Stage IIA Cutaneous Melanoma AJCC V8
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Ipilimumab
Nivolumab
Pembrolizumab
Quadrivalent Inactivated Influenza Vaccine
Resection
High Vs. Standard Dose Influenza Vaccine in Lung Allograft RecipientsHigh Vs. Standard Dose Influenza Vaccine in Lung Allograft Recipients
Sponsor:
Vanderbilt University Medical Center
Location:
Code:
NCT05215327
Conditions
Immunization; Infection
Transplantation Infection
Influenza
Eligibility Criteria
Sex: All
Age: 16+
Healthy Volunteers: Not accepted
Interventions
High Dose Quadrivalent Inactivated Influenza Vaccine
Standard Dose Quadrivalent Inactivated Influenza Vaccine
pBI-11 & TA-HPV (With Pembrolizumab as Treatment for Patients w/Advanced, PD-L1 CPS≥1, hrHPV+ Oropharyngeal CancerpBI-11 & TA-HPV (With Pembrolizumab as Treatment for Patients w/Advanced, PD-L1 CPS≥1, hrHPV+ Oropharyngeal Cancer
Sponsor:
Michael K. Gibson
Location:
Code:
NCT05799144
Conditions
Metastatic Oropharyngeal Carcinoma
Recurrent Oropharyngeal Carcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
DNA Vaccine
Human Papillomavirus Tumor Antigen Vaccine
Pembrolizumab
Computed Tomography (CT)
Magnetic Resonance Imaging (MRI)
Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast CancerTesting the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
Sponsor:
National Cancer Institute (NCI)
Location:
Code:
NCT03606967
Conditions
Anatomic Stage IV Breast Cancer AJCC v8
Invasive Breast Carcinoma
Metastatic Triple-Negative Breast Carcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biopsy
Biospecimen Collection
Carboplatin
Computed Tomography
Durvalumab
Evaluation of Trimer 4571 Therapeutic Vaccination in Adults Living with HIV on Suppressive Antiretroviral TherapyEvaluation of Trimer 4571 Therapeutic Vaccination in Adults Living with HIV on Suppressive Antiretroviral Therapy
Sponsor:
Madhu Chhanda Choudhary
Location:
Code:
NCT04985760
Conditions
HIV Infections
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Trimer 4571 vaccine 100mcg with 500mcg alum adjuvant
Placebo control for Trimer 4571 vaccine 100mcg with 500mcg alum adjuvant
Trimer 4571 vaccine 500mcg with 500mcg alum adjuvant
Placebo control for Trimer 4571 vaccine 500mcg with 500mcg alum adjuvant
Real-World Effectiveness of Perinatal RSV ImmunoprophylaxisReal-World Effectiveness of Perinatal RSV Immunoprophylaxis
Sponsor:
Yale University
Location:
Code:
NCT06172660
Conditions
RSV Infection
Eligibility Criteria
Sex: All
Age: 0 - 12
Healthy Volunteers: Not accepted
Interventions
Nirsevimab
Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent GlioblastomaPembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma
Sponsor:
Jonsson Comprehensive Cancer Center
Location:
Code:
NCT04201873
Conditions
Recurrent Glioblastoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Dendritic Cell Tumor Cell Lysate Vaccine
Pembrolizumab
Placebo Administration
Poly ICLC
Repeat BCG Vaccinations for the Treatment of Pediatric Type 1 DiabetesRepeat BCG Vaccinations for the Treatment of Pediatric Type 1 Diabetes
Sponsor:
Massachusetts General Hospital
Location:
Code:
NCT05180591
Conditions
Diabetes Mellitus, Type 1
Diabetes Type1
Autoimmune Diabetes
Eligibility Criteria
Sex: All
Age: 12 - 17
Healthy Volunteers: Not accepted
Interventions
Bacillus Calmette-Guérin
Saline Injection
VZV in the Enteric Nervous System: Pathogenesis and ConsequencesVZV in the Enteric Nervous System: Pathogenesis and Consequences
Sponsor:
Vanderbilt University Medical Center
Location:
Code:
NCT05550194
Conditions
Achalasia
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
ValACYclovir 1000 MG
Shingrix
RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)RNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)
Sponsor:
University of Florida
Location:
Code:
NCT06389591
Conditions
Recurrent Glioblastoma
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
pp65 RNA loaded lipid particles, pp65 RNA-LPs (Drug Product 1 or DP1)
RNA loaded lipid particles, RNA-LPs (Drug Product 2 or DP2)
What are vaccine clinical trials?
Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.
Importance of clinical trials for vaccines
Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.
Types of interventions studied in vaccine clinical trials
Vaccine clinical trials investigate a wide array of vaccines. These interventions aim to stimulate the immune system to produce a protective response against specific pathogens. Some common types of interventions studied in vaccine clinical trials include:
Preventive vaccines
These trials focus on vaccines designed to prevent infectious diseases, such as the COVID-19 vaccine, the Western Equine Encephalitis (WEE) vaccine, and vaccines against Respiratory Syncytial Virus (RSV).
Therapeutic vaccines
Some trials study vaccines intended to treat existing conditions, such as vaccines targeting ovarian cancer, follicular lymphoma, and pancreatic cancer. These vaccines aim to stimulate the immune system to attack cancer cells.
Combination vaccine trials
These studies explore the safety and efficacy of combining different vaccines, such as measles, mumps, rubella, and chickenpox vaccines, to improve immunity with fewer injections.
Eligibility and participation in vaccine clinical trials
Eligibility for vaccine clinical trials varies depending on the study's focus. Trials may be open to specific age groups, genders, and health conditions. Both healthy volunteers and those with the condition being targeted by the vaccine may be eligible to participate. Criteria often include age, health status, and history of vaccination.
What to expect when participating in a vaccine clinical trial
Participants can expect to undergo initial screenings to determine eligibility, receive detailed information about the study, and be monitored for their response to the vaccine and any side effects. Trials may involve receiving the investigational vaccine or a placebo and attending follow-up appointments to assess health outcomes.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
How to enroll in a vaccine clinical trial
Enrolling in a clinical trial for vaccines through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify Your Trial: Use our search bar or filters to find clinical trials for vaccines that match your interests and needs. This first step simplifies the process of finding relevant research studies tailored to your needs.
- Select Your Preferred Location:To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.