Vaccine Clinical Trials
Find clinical trials for vaccine. Search for vaccine clinical trials in different cities and states across the United States.
Evaluation of Human Immune Responses Vaccination in Patients With Lymphoma
Sponsor:
Emory University
Location:
Code:
NCT03501576
Conditions
Chronic Lymphocytic Leukemia
Diffuse Large B-Cell Lymphoma
Follicular Lymphoma
Mantle Cell Lymphoma
Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
I
n
a
c
t
A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.
Sponsor:
Moderna
Location:
Code:
NCT05683457
Conditions
Cytomegalovirus Infection
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
m
R
N
A
-
Concurrent WOKVAC Vaccination, Chemotherapy, and HER2-Targeted Monoclonal Antibody Therapy Before Surgery for the Treatment of Patients With Breast Cancer
Sponsor:
University of Washington
Location:
Code:
NCT04329065
Conditions
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage IA Breast Cancer AJCC v8
Anatomic Stage IB Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage IIA Breast Cancer AJCC v8
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
p
U
M
V
C
A Multiple Antigen Vaccine (STEMVAC) for the Treatment of Patients With Stage IV Non-Small Cell Lung Cancer
Sponsor:
University of Washington
Location:
Code:
NCT05242965
Conditions
Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC v8
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
C
D
1
0
5
Novel RNA-nanoparticle Vaccine for the Treatment of Early Melanoma Recurrence Following Adjuvant Anti-PD-1 Antibody Therapy
Sponsor:
University of Florida
Location:
Code:
NCT05264974
Conditions
Melanoma
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
A
u
t
o
l
Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma
Sponsor:
Baylor College of Medicine
Location:
Code:
NCT04157127
Conditions
Pancreatic Adenocarcinoma
Pancreatic Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
A
u
t
o
l
Study of the Plasmodium Vivax Transmission-blocking Vaccine Pvs230D1-EPA/Matrix-M to Assess Safety, Immunogenicity, and Transmission-blocking Activity in Healthy Malaria-naive Adults
Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Location:
Code:
NCT05913973
Conditions
Malaria
Eligibility Criteria
Sex: All
Age: 18 - 50
Healthy Volunteers: Not accepted
Interventions
P
v
s
2
3
Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma
Sponsor:
Jonsson Comprehensive Cancer Center
Location:
Code:
NCT04201873
Conditions
Recurrent Glioblastoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
D
e
n
d
r
Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
Sponsor:
National Cancer Institute (NCI)
Location:
Code:
NCT06253520
Conditions
Metastatic Solid Cancers
Colorectal Cancer
Breast Cancer
Non-Small Cell Lung Cancer
Gastrointestinal Cancer
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
A
l
d
e
s
What are vaccine clinical trials?
Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.
Importance of clinical trials for vaccines
Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.
Types of interventions studied in vaccine clinical trials
Vaccine clinical trials investigate a wide array of vaccines. These interventions aim to stimulate the immune system to produce a protective response against specific pathogens. Some common types of interventions studied in vaccine clinical trials include:
Preventive vaccines
These trials focus on vaccines designed to prevent infectious diseases, such as the COVID-19 vaccine, the Western Equine Encephalitis (WEE) vaccine, and vaccines against Respiratory Syncytial Virus (RSV).
Therapeutic vaccines
Some trials study vaccines intended to treat existing conditions, such as vaccines targeting ovarian cancer, follicular lymphoma, and pancreatic cancer. These vaccines aim to stimulate the immune system to attack cancer cells.
Combination vaccine trials
These studies explore the safety and efficacy of combining different vaccines, such as measles, mumps, rubella, and chickenpox vaccines, to improve immunity with fewer injections.
Eligibility and participation in vaccine clinical trials
Eligibility for vaccine clinical trials varies depending on the study's focus. Trials may be open to specific age groups, genders, and health conditions. Both healthy volunteers and those with the condition being targeted by the vaccine may be eligible to participate. Criteria often include age, health status, and history of vaccination.
What to expect when participating in a vaccine clinical trial
Participants can expect to undergo initial screenings to determine eligibility, receive detailed information about the study, and be monitored for their response to the vaccine and any side effects. Trials may involve receiving the investigational vaccine or a placebo and attending follow-up appointments to assess health outcomes.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
How to enroll in a vaccine clinical trial
Enrolling in a clinical trial for vaccines through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify Your Trial: Use our search bar or filters to find clinical trials for vaccines that match your interests and needs. This first step simplifies the process of finding relevant research studies tailored to your needs.
- Select Your Preferred Location:To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.