Vaccines Clinical Trials
Find clinical trials for vaccines. Search for vaccines clinical trials in different cities and states across the United States.
Immunosuppression AdjustmentImpact of Immunosuppression Adjustment on COVID-19 Vaccination Response in Kidney Transplant Recipients
Sponsor:
UCLA
Location:
Code:
NCT05060991
Conditions
COVID-19
Immunosuppression
Vaccine Response Impaired
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Reduction in antimetabolite immunosuppression
Influenza VaccineIntralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma
Sponsor:
Carlo Contreras
Location:
Code:
NCT04697576
Conditions
Clinical Stage I Cutaneous Melanoma AJCC V8
Clinical Stage IA Cutaneous Melanoma AJCC V8
Clinical Stage IB Cutaneous Melanoma AJCC V8
Clinical Stage II Cutaneous Melanoma AJCC V8
Clinical Stage IIA Cutaneous Melanoma AJCC V8
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Ipilimumab
Nivolumab
Pembrolizumab
Quadrivalent Inactivated Influenza Vaccine
Resection
VaccinationEvaluation of Human Immune Responses Vaccination in Patients with Lymphoma
Sponsor:
Emory University
Location:
Code:
NCT03501576
Conditions
Chronic Lymphocytic Leukemia
Diffuse Large B-Cell Lymphoma
Follicular Lymphoma
Mantle Cell Lymphoma
Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Inactivated Influenza Vaccine
pBI-11 & TA-HPVpBI-11 & TA-HPV (With Pembrolizumab as Treatment for Patients w/Advanced, PD-L1 CPS≥1, hrHPV+ Oropharyngeal Cancer
Sponsor:
Michael K. Gibson
Location:
Code:
NCT05799144
Conditions
Metastatic Oropharyngeal Carcinoma
Recurrent Oropharyngeal Carcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
DNA Vaccine
Human Papillomavirus Tumor Antigen Vaccine
Pembrolizumab
Computed Tomography (CT)
Magnetic Resonance Imaging (MRI)
ImmunotherapyPlatform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas
Sponsor:
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Location:
Code:
NCT02451982
Conditions
Pancreatic Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Cyclophosphamide
GVAX pancreatic cancer
Nivolumab
Urelumab
BMS-986253
Triple Immune RegimenEvaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1
Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Location:
Code:
NCT06071767
Conditions
HIV-1-infection
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
ChAdOx1.tHIVconsv1
ChAdOx1.HIVconsv62
MVA.tHIVconsv3
MVA.tHIVconsv4
Vesatolimod (VES)
Durvalumab, Tremelimumab, ChemotherapyTesting the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer
Sponsor:
National Cancer Institute (NCI)
Location:
Code:
NCT03606967
Conditions
Anatomic Stage IV Breast Cancer AJCC v8
Invasive Breast Carcinoma
Metastatic Triple-Negative Breast Carcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biopsy Procedure
Biospecimen Collection
Carboplatin
Computed Tomography
Durvalumab
VSV-hIFNβ-NIS, Cyclophosphamide, Ipilimumab, Nivolumab, CemiplimabA Vaccine (VSV-hIFNβ-NIS) with or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma
Sponsor:
Mayo Clinic
Location:
Code:
NCT03017820
Conditions
B-Cell Non-Hodgkin Lymphoma
Histiocytic and Dendritic Cell Neoplasm
Myelodysplastic Syndrome
Previously Treated Myelodysplastic Syndrome
Recurrent Adult Acute Myeloid Leukemia
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biopsy
Biospecimen Collection
Bone Marrow Biopsy
Computed Tomography
Cyclophosphamide
Pembrolizumab & ATL-DCPembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent Glioblastoma
Sponsor:
Jonsson Comprehensive Cancer Center
Location:
Code:
NCT04201873
Conditions
Recurrent Glioblastoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Dendritic Cell Tumor Cell Lysate Vaccine
Pembrolizumab
Placebo Administration
Poly ICLC
RNA-LP VaccinesRNA-Lipid Particle (RNA-LP) Vaccines for Recurrent Adult Glioblastoma (GBM)
Sponsor:
University of Florida
Location:
Code:
NCT06389591
Conditions
Recurrent Glioblastoma
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
pp65 RNA loaded lipid particles, pp65 RNA-LPs (Drug Product 1 or DP1)
RNA loaded lipid particles, RNA-LPs (Drug Product 2 or DP2)
What are vaccine clinical trials?
Vaccine clinical trials are research studies conducted to evaluate the safety, efficacy, and immunogenicity (the ability to provoke an immune response) of vaccines aimed at preventing diseases. These trials are crucial for developing new vaccines against various conditions, including infectious diseases, cancers, and chronic conditions.
Importance of clinical trials for vaccines
Clinical trials for vaccines play a vital role in ensuring that new vaccines are both safe and effective before they are made available to the public. These trials help identify the best dosing schedules, understand how the immune system responds to the vaccine, and determine any potential side effects. They are fundamental in the fight against emerging infectious diseases, as well as in the development of therapeutic vaccines for conditions like cancer.
Types of interventions studied in vaccine clinical trials
Vaccine clinical trials investigate a wide array of vaccines. These interventions aim to stimulate the immune system to produce a protective response against specific pathogens. Some common types of interventions studied in vaccine clinical trials include:
Preventive vaccines
These trials focus on vaccines designed to prevent infectious diseases, such as the COVID-19 vaccine, the Western Equine Encephalitis (WEE) vaccine, and vaccines against Respiratory Syncytial Virus (RSV).
Therapeutic vaccines
Some trials study vaccines intended to treat existing conditions, such as vaccines targeting ovarian cancer, follicular lymphoma, and pancreatic cancer. These vaccines aim to stimulate the immune system to attack cancer cells.
Combination vaccine trials
These studies explore the safety and efficacy of combining different vaccines, such as measles, mumps, rubella, and chickenpox vaccines, to improve immunity with fewer injections.
Eligibility and participation in vaccine clinical trials
Eligibility for vaccine clinical trials varies depending on the study's focus. Trials may be open to specific age groups, genders, and health conditions. Both healthy volunteers and those with the condition being targeted by the vaccine may be eligible to participate. Criteria often include age, health status, and history of vaccination.
What to expect when participating in a vaccine clinical trial
Participants can expect to undergo initial screenings to determine eligibility, receive detailed information about the study, and be monitored for their response to the vaccine and any side effects. Trials may involve receiving the investigational vaccine or a placebo and attending follow-up appointments to assess health outcomes.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
How to enroll in a vaccine clinical trial
Enrolling in a clinical trial for vaccines through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify Your Trial: Use our search bar or filters to find clinical trials for vaccines that match your interests and needs. This first step simplifies the process of finding relevant research studies tailored to your needs.
- Select Your Preferred Location:To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.