Stem Cells Clinical Trials
Find clinical trials for stem cells. Search for stem cells clinical trials in different cities and states across the United States.
Ladarixin With Sotorasib in Advanced NSCLC
Sponsor:
NYU Langone Health
Location:
Code:
NCT05815173
Conditions
Advanced Non-small Cell Lung Cancer With KRAS G12C Mutation
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Sotorasib
Ladarixin
Exercise Program (TEAM Me) for the Improvement of Movement and Mobility in Pediatric and Adolescent and Young Adult Patients With Cancer Undergoing a Blood Stem Cell Transplant
Sponsor:
M.D. Anderson Cancer Center
Location:
Code:
NCT04678427
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Eligibility Criteria
Sex: All
Age: 6 - 29
Healthy Volunteers: Not accepted
Interventions
6 Minute Walk Functional Test
Behavioral Intervention
Survey Administration
Timed Get Up and Go Test
Brentuximab Vedotin and Nivolumab for the Treatment of Relapsed/Refractory Classic Hodgkin Lymphoma Previously Treated With Brentuximab Vedotin or Checkpoint Inhibitors
Sponsor:
Emory University
Location:
Code:
NCT05039073
Conditions
Recurrent Classic Hodgkin Lymphoma
Refractory Classic Hodgkin Lymphoma
Eligibility Criteria
Sex: All
Age: 12+
Healthy Volunteers: Not accepted
Interventions
Brentuximab Vedotin
Hematopoietic Cell Transplantation
Nivolumab
Quality-of-Life Assessment
Questionnaire Administration
Mobilization of Stem Cells With G-CSF and Mozobil in Patients With End Stage Liver Disease
Sponsor:
Proteonomix, Inc.
Location:
Code:
NCT01711073
Conditions
End Stage Liver DIsease
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Mobilization with G-CSF and Mozobil
Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes
Sponsor:
Fred Hutchinson Cancer Center
Location:
Code:
NCT03399773
Conditions
Acute Biphenotypic Leukemia
Acute Lymphoblastic Leukemia
Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Hematopoietic and Lymphoid Cell Neoplasm
Myelodysplastic Syndrome
Eligibility Criteria
Sex: All
Age: 10 - 65
Healthy Volunteers: Not accepted
Interventions
Dilanubicel
Cyclophosphamide
Fludarabine
Thiotepa
Total-Body Irradiation
TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis
Sponsor:
City of Hope Medical Center
Location:
Code:
NCT04380831
Conditions
Systemic Scleroderma
Eligibility Criteria
Sex: All
Age: 18 - 65
Healthy Volunteers: Not accepted
Interventions
Allogeneic Hematopoietic Stem Cell Transplantation
Cyclophosphamide
Intensity-Modulated Radiation Therapy
Total-Body Irradiation
Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation
Sponsor:
Sawa Ito, MD
Location:
Code:
NCT06529731
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Interferon gamma-1b
Donor Leukocyte Infusion (DLI)
Prospect Eval of Efficacy of CMV-TCIP Direct Letermovir Prophylax After Allogen Hemato Cell Transpla
Sponsor:
UCLA
Location:
Code:
NCT06453460
Conditions
CMV
Allogeneic Stem Cell Transplantation
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Letermovir
CMV T Cell Immunity Panel (CMV-TCIP)
CMV DNA PCR
Allogenic Adipose-Derived Mesenchymal Stem Cells for the Treatment of Recurrent Glioblastoma or Recurrent Astrocytoma in Patients Undergoing Craniotomy
Sponsor:
Mayo Clinic
Location:
Code:
NCT05789394
Conditions
Recurrent Glioblastoma, IDH-Wildtype
Recurrent Astrocytoma, IDH-Mutant, Grade 4
Astrocytoma, Grade IV
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Allogeneic Adipose-derived Mesenchymal Stem Cells
Biospecimen Collection
Craniotomy
Magnetic Resonance Imaging
Ommaya Reservoir Tap
Effects of Selected Vegetable and Herb Mix (SV) on Advanced Non-small Cell Lung Cancer
Sponsor:
Sun Farm Corporation
Location:
Code:
NCT00246727
Conditions
Non-small Cell Lung Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Selected Vegetable and Herb Mix
What are stem cell clinical trials?
Stem cell clinical trials are research studies that explore the therapeutic potential of stem cells for treating a wide range of diseases and conditions. These trials investigate various types of stem cells, including embryonic stem cells, induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), hematopoietic stem cells (HSCs), and adipose-derived stem cells. These trials aim to develop treatments for a wide range of conditions, such as cardiovascular diseases, neurological disorders, autoimmune diseases, orthopedic injuries, Alzheimer's disease, Crohn's disease and cancer.
Importance of clinical trials for stem cells
Clinical trials for stem cells are crucial for advancing regenerative medicine and offering hope for patients with conditions that are currently difficult to treat. These studies help to determine the safety, efficacy, and optimal use of stem cell therapies, potentially leading to breakthroughs in the treatment of chronic diseases, immune disorders, and injuries. They play a vital role in understanding how stem cells can be used to repair damaged tissues, treat malignancies, and improve patient outcomes.
Types of interventions studied in stem cells clinical trials
Stem cell clinical trials investigate a variety of interventions aimed at utilizing the unique properties of stem cells for therapeutic purposes. Some common types of interventions studied in stem cell clinical trials include:
Allogeneic and autologous stem cell transplantation
These trials assess the use of stem cells derived from both the patient (autologous) and donors (allogeneic) for the treatment of hematologic diseases, solid tumors, and immune disorders, aiming to restore normal cell function and immune response.
Cell replacement therapies
Some trials focus on using stem cells to replace or repair damaged or dysfunctional cells or tissues in the body. For example, mesenchymal stem cells (MSCs) may be used to regenerate bone, cartilage, or muscle tissue in orthopedic conditions, while hematopoietic stem cell transplants are used to replace damaged blood-forming cells in conditions such as leukemia or aplastic anemia.
Tissue engineering and regenerative medicine
Clinical trials are investigating stem cells for their potential to stimulate tissue regeneration and repair. This includes approaches such as seeding stem cells onto scaffolds or matrices to create tissue-engineered constructs for transplantation. Research includes developing bioengineered tissues and organs using stem cells to replace damaged tissues in conditions like Crohn's disease-related fistulas, cartilage defects, and chronic pancreatitis.
Gene therapy
Gene-modified stem cell therapies are being investigated for their potential in treating genetic disorders, metabolic diseases, and certain types of cancer. For example, genetically modified hematopoietic stem cells may be used to treat inherited blood disorders like sickle cell disease or beta-thalassemia.
Neuroprotection and neuroregeneration
Clinical trials are studying stem cell therapies for their potential to protect and regenerate neurons in neurodegenerative diseases and neurological injuries. This includes approaches such as transplantation of neural stem cells or mesenchymal stem cells, as well as promoting endogenous neurogenesis and synaptic repair.
Eligibility and participation in stem cells clinical trials
Eligibility for stem cells clinical trials varies widely, targeting specific diseases, age groups, and health conditions. Trials may be open to individuals with specific diagnoses, such as leukemia, Alzheimer's disease, or organ-specific injuries. Criteria often include the stage of the disease, previous treatments, and overall health status.
What to expect when participating in a stem cells clinical trial
Participants can expect thorough screening for eligibility, comprehensive information about the study's purpose and procedures, and close monitoring throughout the trial. This may involve receiving stem cell infusions, undergoing surgical procedures for tissue transplantation, and participating in follow-up assessments to monitor the therapy's effectiveness and any side effects.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
How to enroll in a stem cell clinical trial
Enrolling in a stem cell clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify Your Trial: Use our search function or filters to find clinical trials that match your medical condition and interest in stem cell therapy. This first step simplifies the process of finding relevant research studies tailored to your needs.
- Select Your Preferred Location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore Study Details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the Health Profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the Application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.