Find clinical trials for stem cells. Search for stem cells clinical trials in different cities and states across the United States.
Sponsor:
medac GmbH
Location:
Code:
NCT05534620
Conditions
Acute Myeloid Leukaemia (AML)
Myelodysplastic Syndrome (MDS)
Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Treosulfan
Fludarabine
Sponsor:
Fred Hutchinson Cancer Center
Location:
Code:
NCT04375631
Conditions
Recurrent Acute Myeloid Leukemia
Recurrent Chronic Myelomonocytic Leukemia
Recurrent Myelodysplastic Syndrome
Refractory Acute Myeloid Leukemia
Refractory Chronic Myelomonocytic Leukemia
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Cladribine
Cyclophosphamide
Cyclosporine
Cytarabine
Filgrastim
Sponsor:
St. Jude Children's Research Hospital
Location:
Code:
NCT04881240
Conditions
Acute Lymphoblastic Leukemia, in Relapse
Acute Lymphoblastic Leukemia, Refractory
Pediatric ALL
Eligibility Criteria
Sex: All
Age: 0 - 21
Healthy Volunteers: Not accepted
Interventions
CD19-CAR(Mem) T-cells
Cyclophosphamide
Fludarabine
Mesna
CliniMACS
Sponsor:
Masonic Cancer Center, University of Minnesota
Location:
Code:
NCT06377540
Conditions
Autologous Stem Cell Transplant
Classic Hodgkin Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Pembrolizumab
Autologous stem cell transplant
Carmustine
Etoposide
Cytarabine
Sponsor:
M.D. Anderson Cancer Center
Location:
Code:
NCT04678427
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Eligibility Criteria
Sex: All
Age: 6 - 29
Healthy Volunteers: Not accepted
Interventions
6 Minute Walk Functional Test
Behavioral Intervention
Survey Administration
Timed Get Up and Go Test
Stem cell clinical trials are research studies that explore the therapeutic potential of stem cells for treating a wide range of diseases and conditions. These trials investigate various types of stem cells, including embryonic stem cells, induced pluripotent stem cells (iPSCs), mesenchymal stem cells (MSCs), hematopoietic stem cells (HSCs), and adipose-derived stem cells. These trials aim to develop treatments for a wide range of conditions, such as cardiovascular diseases, neurological disorders, autoimmune diseases, orthopedic injuries, Alzheimer's disease, Crohn's disease and cancer.
Clinical trials for stem cells are crucial for advancing regenerative medicine and offering hope for patients with conditions that are currently difficult to treat. These studies help to determine the safety, efficacy, and optimal use of stem cell therapies, potentially leading to breakthroughs in the treatment of chronic diseases, immune disorders, and injuries. They play a vital role in understanding how stem cells can be used to repair damaged tissues, treat malignancies, and improve patient outcomes.
Stem cell clinical trials investigate a variety of interventions aimed at utilizing the unique properties of stem cells for therapeutic purposes. Some common types of interventions studied in stem cell clinical trials include:
These trials assess the use of stem cells derived from both the patient (autologous) and donors (allogeneic) for the treatment of hematologic diseases, solid tumors, and immune disorders, aiming to restore normal cell function and immune response.
Some trials focus on using stem cells to replace or repair damaged or dysfunctional cells or tissues in the body. For example, mesenchymal stem cells (MSCs) may be used to regenerate bone, cartilage, or muscle tissue in orthopedic conditions, while hematopoietic stem cell transplants are used to replace damaged blood-forming cells in conditions such as leukemia or aplastic anemia.
Clinical trials are investigating stem cells for their potential to stimulate tissue regeneration and repair. This includes approaches such as seeding stem cells onto scaffolds or matrices to create tissue-engineered constructs for transplantation. Research includes developing bioengineered tissues and organs using stem cells to replace damaged tissues in conditions like Crohn's disease-related fistulas, cartilage defects, and chronic pancreatitis.
Gene-modified stem cell therapies are being investigated for their potential in treating genetic disorders, metabolic diseases, and certain types of cancer. For example, genetically modified hematopoietic stem cells may be used to treat inherited blood disorders like sickle cell disease or beta-thalassemia.
Clinical trials are studying stem cell therapies for their potential to protect and regenerate neurons in neurodegenerative diseases and neurological injuries. This includes approaches such as transplantation of neural stem cells or mesenchymal stem cells, as well as promoting endogenous neurogenesis and synaptic repair.
Eligibility for stem cells clinical trials varies widely, targeting specific diseases, age groups, and health conditions. Trials may be open to individuals with specific diagnoses, such as leukemia, Alzheimer's disease, or organ-specific injuries. Criteria often include the stage of the disease, previous treatments, and overall health status.
Participants can expect thorough screening for eligibility, comprehensive information about the study's purpose and procedures, and close monitoring throughout the trial. This may involve receiving stem cell infusions, undergoing surgical procedures for tissue transplantation, and participating in follow-up assessments to monitor the therapy's effectiveness and any side effects.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
Enrolling in a stem cell clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started: