Find clinical trials for Alzheimer's Disease. Search for Alzheimer's Disease clinical trials in different cities and states across the United States.
Sponsor:
Douglas Scharre
Location:
Code:
NCT03019757
Conditions
Alzheimer's Disease
Lewy Body Dementia
Parkinson's Disease
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
DaTscan
F18-AV-45
FDG-PET
APOE genotype
Polysomnogram
Sponsor:
St. Joseph's Hospital and Medical Center, Phoenix
Location:
Code:
NCT04032626
Conditions
Cognitive Impairment, Mild
Cognitive Dysfunction
Amyloid Plaque
Neurodegeneration
Inflammation, Brain
Eligibility Criteria
Sex: All
Age: 50 - 70+
Healthy Volunteers: Not accepted
Interventions
Lenalidomide 10 mg
Placebo
Sponsor:
VA Boston Healthcare System
Location:
Code:
NCT02957227
Conditions
Mild Cognitive Impairment
Eligibility Criteria
Sex: All
Age: 50 - 70+
Healthy Volunteers: Not accepted
Interventions
No intervention is part of this study but patients use an EEG device during observational data collection.
Sponsor:
Sunnybrook Health Sciences Centre
Location:
Code:
NCT02085265
Conditions
Alzheimer's Disease
Eligibility Criteria
Sex: All
Age: 50+
Healthy Volunteers: Not accepted
Interventions
Perindopril
Telmisartan
Sponsor:
Rotman Research Institute at Baycrest
Location:
Code:
NCT03665831
Conditions
Major Depressive Disorder
Alzheimer Disease
Mild Cognitive Impairment
Eligibility Criteria
Sex: All
Age: 60+
Healthy Volunteers: Not accepted
Interventions
Brainsway H1-Coil Deep TMS System
Sponsor:
Brent Forester
Location:
Code:
NCT03926520
Conditions
Alzheimer Dementia
Agitation,Psychomotor
Eligibility Criteria
Sex: All
Age: 40+
Healthy Volunteers: Not accepted
Interventions
Electroconvulsive Therapy (ECT)
Sponsor:
Passage Bio, Inc.
Location:
Code:
NCT04747431
Conditions
Frontotemporal Dementia
FTD
FTD-GRN
Dementia Frontotemporal
Eligibility Criteria
Sex: All
Age: 35 - 70+
Healthy Volunteers: Not accepted
Interventions
PBFT02
Sponsor:
The University of Texas Health Science Center at San Antonio
Location:
Code:
NCT04629495
Conditions
Mild Cognitive Impairment
Alzheimer Disease
Eligibility Criteria
Sex: All
Age: 55 - 70+
Healthy Volunteers: Not accepted
Interventions
Rapamycin
Placebo
Alzheimer's disease clinical trials are research studies aimed at finding new ways to prevent, diagnose, and treat Alzheimer's disease. These trials are essential for developing new medications, identifying risk factors, and improving the quality of life for those affected by Alzheimer's.
Clinical trials are the primary method through which new treatments for Alzheimer’s disease are discovered and validated. These trials not only test the effectiveness and safety of new drugs but also explore ways to detect Alzheimer's early, improve symptom management, and prevent the disease from developing.
Alzheimer's disease clinical trials are diverse in their objectives and study design. They address different aspects of the disease from prevention and diagnosis to treatment. The main types of clinical trials conducted for Alzheimer’s disease are:
Interventional trials examine how specific treatments impact the health outcomes of individuals with Alzheimer's disease. These trials actively involve administering new drugs, medical devices, or other treatments to participants to observe their effects on the disease's progression, symptoms, or both. The goal is to determine whether these new interventions are safe and more effective than current treatments.
Unlike interventional trials, observational studies do not involve administering a specific treatment. Instead, researchers observe and gather information on participants over time to understand better how Alzheimer's disease progresses and how different factors may influence its development and trajectory. These studies can help identify new risk factors, biomarkers for early detection, and potential targets for future treatments.
Prevention trials are designed to investigate ways to prevent Alzheimer’s disease in people who do not have the disease but may be at higher risk of developing it. These trials explore whether factors such as lifestyle changes, medications, or vaccines can reduce the risk of developing Alzheimer's. They are critical for identifying strategies that could potentially stop the disease before it starts.
Quality of life studies are designed to improve the daily lives of people living with Alzheimer’s and their caregivers. These trials might test strategies for managing symptoms, enhancing communication skills, reducing caregiver stress, and improving overall well-being. By focusing on the human aspect of Alzheimer’s care, these studies aim to find better ways to support individuals and families navigating the challenges of the disease.
Alzheimer's disease clinical trials are focused on evaluating a variety of treatments to address different aspects of the disease. These treatments include:
Clinical research is constantly developing and testing new drugs that target the biological mechanisms believed to contribute to Alzheimer's disease. These trials test new drugs designed to slow the progression of Alzheimer's, improve symptoms, or target the disease's underlying causes.
Clinical trials also investigate interventions that do not involve medication, such as cognitive therapy, exercise, dietary changes, and activities to improve social engagement. These are aimed at improving cognitive function and overall quality of life for patients with Alzheimer's.
Clinical research is being conducted on new methods for early and accurate diagnosis of Alzheimer's, including advanced imaging techniques and tests to identify biological markers of the disease.
These trials are exploring ways to support caregivers of Alzheimer's patients by developing effective caregiving strategies, providing resources, and offering support services. The aim is to reduce the burden on caregivers and improve care for patients.
Individuals with Alzheimer's disease, those at risk of developing the disease, and healthy volunteers can all participate in different types of clinical trials. Eligibility criteria vary depending on the trial's focus and objectives, including age, stage of disease, and overall health.
Participants in Alzheimer's disease clinical trials can expect to undergo a thorough screening process to determine eligibility, followed by detailed information about the study's purpose, procedures, potential risks, and benefits. During the trial, participants might receive specific interventions and be closely monitored through regular health assessments and follow-ups to evaluate the treatment's effectiveness and any side effects.
Unsure about participating in clinical trials? Dive into our comprehensive guide to learn about the process, benefits, and potential impact of your involvement. Get the facts you need to make an informed decision today!
Enrolling in a clinical trial for Alzheimer’s disease through our platform is a straightforward and user-friendly process. Here's how to get started: