Discover 2,936 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Sponsor:
Children's Hospital Medical Center, Cincinnati
Location:
Code:
NCT03789591
Conditions
Sickle Cell Disease
Sickle Cell Anemia
Eligibility Criteria
Sex: All
Age: 6 - 21
Healthy Volunteers: Not accepted
Interventions
Hydroxyurea
Sponsor:
UCB Biopharma SRL
Location:
Code:
NCT05063162
Conditions
Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Rozanolixizumab
Placebo
Sponsor:
Oana Danciu
Location:
Code:
NCT05467891
Conditions
Locoregional Recurrence
Hormone Receptor-positive Breast Cancer
HER2-negative Breast Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Ribociclib
Fulvestrant
Anastrozole
Letrozole
Exemestane
Sponsor:
Eli Lilly and Company
Location:
Code:
NCT05999994
Conditions
Neoplasms
Child
Adolescent
Eligibility Criteria
Sex: All
Age: 1 - 39
Healthy Volunteers: Not accepted
Interventions
Ramucirumab
Cyclophosphamide
Vinorelbine
Gemcitabine
Docetaxel
Sponsor:
XSpline S.p.A.
Location:
Code:
NCT05327062
Conditions
Cardiac Resynchronization Therapy
Chronic Heart Failure
Left Bundle-Branch Block
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment
With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.
Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.
The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.
Boston is renowned for its extensive clinical research across a wide array of medical conditions, driven by its world-class hospitals and research institutions.
Boston's Dana-Farber Cancer Institute, Massachusetts General Hospital Cancer Center, and other top institutions are renowned for conducting cutting-edge cancer research. They lead oncology clinical trials focusing on a wide array of cancers such as breast, lung, colorectal, and melanoma.
These trials explore innovative treatments, including CAR-T cell therapy, immune checkpoint inhibitors, precision oncology, and experimental drugs designed to target specific genetic mutations in tumors.
Boston is a leader in cardiovascular research, addressing diseases such as coronary artery disease, heart failure, hypertension, and atrial fibrillation. Institutions like the Brigham and Women’s Hospital Heart & Vascular Center and Beth Israel Deaconess Medical Center focus on clinical trials investigating new medications, minimally invasive surgical procedures, and medical devices like left ventricular assist devices (LVADs) and transcatheter aortic valve replacements (TAVR). Studies often explore novel biomarkers for early detection and prevention strategies.
Boston's status as a hub for neuroscience research is underscored by its extensive studies into Alzheimer’s disease, Parkinson’s disease, ALS (Lou Gehrig's disease), epilepsy, and multiple sclerosis (MS).
Major hospitals such as Massachusetts General Hospital and Boston Children's Hospital lead clinical trials on disease-modifying therapies, neuroprotective agents, and gene-editing technologies. Researchers also investigate new treatments for stroke recovery and traumatic brain injuries.
The city’s leading research centers conduct numerous trials targeting autoimmune conditions such as rheumatoid arthritis, lupus, and Crohn's disease. These trials frequently test advanced biologic therapies, monoclonal antibodies, and small molecule drugs designed to dampen the immune response or reset immune system function. Personalized approaches like precision immunotherapy and the use of stem cells are also areas of active exploration in Boston.
Boston has long been at the forefront of diabetes research, with a particular focus on innovative treatments for both Type 1 and Type 2 diabetes. Trials often explore new forms of insulin, artificial pancreas technologies, continuous glucose monitors, and regenerative medicine approaches like beta-cell transplantation. Endocrine research also spans conditions such as thyroid disorders, obesity, and metabolic syndrome.
Boston’s research institutions are committed to tackling rare diseases, with several clinical trials focused on orphan diseases such as cystic fibrosis, Duchenne muscular dystrophy, and other rare genetic conditions. These trials often test gene therapies, CRISPR-based gene editing, and experimental drugs designed to address the underlying causes of these conditions.
Clinical trials in Boston adhere to rigorous guidelines and regulations to ensure participant safety, ethical conduct, and scientific integrity. These trials must comply with federal standards set by the FDA and HHS, as well as the Common Rule for human research ethics. Institutions conducting clinical trials must have Institutional Review Boards (IRBs) that review and approve research protocols to ensure they prioritize participant rights and safety. Additionally, the informed consent process ensures that participants fully understand the risks and benefits before enrolling.
Massachusetts also enforces strict state-specific regulations, particularly through the Department of Public Health (DPH) and HIPAA guidelines for patient privacy. Researchers in Boston follow Good Clinical Practice (GCP) standards, and all clinical trials are required to register on ClinicalTrials.gov for transparency.
Participating in a clinical trial offers a unique chance to access cutting-edge treatments and therapies before they are widely available. During a clinical trial, participants benefit from expert care provided by top healthcare professionals, ensuring personalized attention and thorough monitoring throughout the study.
Clinical trial participation plays a crucial role in advancing medical research, often leading to groundbreaking discoveries in treatment and prevention. By joining a trial, individuals make a meaningful contribution to the development of new medical knowledge, ultimately improving future healthcare for others.
Worried about the risks of participating in a clinical trial? Read our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
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