Discover 2,943 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Sponsor:
Mclean Hospital
Location:
Code:
NCT06477406
Conditions
Endometriosis
Eligibility Criteria
Sex: All
Age: 21+
Healthy Volunteers: Not accepted
Interventions
Cannabidiol
Placebo
Sponsor:
Mclean Hospital
Location:
Code:
NCT05457465
Conditions
Bipolar Disorder
Eligibility Criteria
Sex: All
Age: 18 - 55
Healthy Volunteers: Not accepted
Interventions
Cannabidiol
Sponsor:
Mclean Hospital
Location:
Code:
NCT04075435
Conditions
Alzheimer Disease
Anxiety
Agitation,Psychomotor
Eligibility Criteria
Sex: All
Age: 55 - 70+
Healthy Volunteers: Not accepted
Interventions
high CBD/low THC sublingual solution
Sponsor:
Staci Gruber, Ph.D.
Location:
Code:
NCT03984565
Conditions
Chronic Pain
Eligibility Criteria
Sex: All
Age: 21+
Healthy Volunteers: Not accepted
Interventions
Cannabidiol
Placebo
Sponsor:
Sabine Mueller, MD, PhD
Location:
Code:
NCT05465174
Conditions
Craniopharyngioma, Child
Craniopharyngioma
Recurrent Craniopharyngioma
Eligibility Criteria
Sex: All
Age: 1 - 39
Healthy Volunteers: Not accepted
Interventions
Nivolumab
Tovorafenib
Sponsor:
Incyte Corporation
Location:
Code:
NCT06585774
Conditions
Chronic Graft-versus-host-disease
Eligibility Criteria
Sex: All
Age: 12+
Healthy Volunteers: Not accepted
Interventions
INCA034176
Placebo
Corticosteroids
Sponsor:
Rigel Pharmaceuticals
Location:
Code:
NCT06161974
Conditions
High Grade Glioma
Astrocytoma
Astrocytoma, Grade III
Astrocytoma, Grade IV
Diffuse Intrinsic Pontine Glioma
Eligibility Criteria
Sex: All
Age: 12 - 39
Healthy Volunteers: Not accepted
Interventions
Olutasidenib + TMZ
Sponsor:
Regeneron Pharmaceuticals
Location:
Code:
NCT06091865
Conditions
Diffuse Large B-cell Lymphoma (DLBCL)
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Odronextamab
Rituximab
Cyclophosphamide
Doxorubicin
Vincristine
Sponsor:
Brigham and Women's Hospital
Location:
Code:
NCT06299774
Conditions
Emergency Medical Services
Emergency Department Visits
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Emergency care at home
Emergency care at a brick-and-mortar emergency department
Sponsor:
Massachusetts General Hospital
Location:
Code:
NCT06375265
Conditions
Insomnia
Postoperative Delirium
Delayed Neurocognitive Recovery
Postoperative Neurocognitive Disorder
Eligibility Criteria
Sex: All
Age: 65+
Healthy Volunteers: Not accepted
Interventions
digital Cognitive Behavioral Therapy for Insomnia (dCBT-I)
Sleep Health Education
With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.
Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.
The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.
Boston is renowned for its extensive clinical research across a wide array of medical conditions, driven by its world-class hospitals and research institutions.
Boston's Dana-Farber Cancer Institute, Massachusetts General Hospital Cancer Center, and other top institutions are renowned for conducting cutting-edge cancer research. They lead oncology clinical trials focusing on a wide array of cancers such as breast, lung, colorectal, and melanoma.
These trials explore innovative treatments, including CAR-T cell therapy, immune checkpoint inhibitors, precision oncology, and experimental drugs designed to target specific genetic mutations in tumors.
Boston is a leader in cardiovascular research, addressing diseases such as coronary artery disease, heart failure, hypertension, and atrial fibrillation. Institutions like the Brigham and Women’s Hospital Heart & Vascular Center and Beth Israel Deaconess Medical Center focus on clinical trials investigating new medications, minimally invasive surgical procedures, and medical devices like left ventricular assist devices (LVADs) and transcatheter aortic valve replacements (TAVR). Studies often explore novel biomarkers for early detection and prevention strategies.
Boston's status as a hub for neuroscience research is underscored by its extensive studies into Alzheimer’s disease, Parkinson’s disease, ALS (Lou Gehrig's disease), epilepsy, and multiple sclerosis (MS).
Major hospitals such as Massachusetts General Hospital and Boston Children's Hospital lead clinical trials on disease-modifying therapies, neuroprotective agents, and gene-editing technologies. Researchers also investigate new treatments for stroke recovery and traumatic brain injuries.
The city’s leading research centers conduct numerous trials targeting autoimmune conditions such as rheumatoid arthritis, lupus, and Crohn's disease. These trials frequently test advanced biologic therapies, monoclonal antibodies, and small molecule drugs designed to dampen the immune response or reset immune system function. Personalized approaches like precision immunotherapy and the use of stem cells are also areas of active exploration in Boston.
Boston has long been at the forefront of diabetes research, with a particular focus on innovative treatments for both Type 1 and Type 2 diabetes. Trials often explore new forms of insulin, artificial pancreas technologies, continuous glucose monitors, and regenerative medicine approaches like beta-cell transplantation. Endocrine research also spans conditions such as thyroid disorders, obesity, and metabolic syndrome.
Boston’s research institutions are committed to tackling rare diseases, with several clinical trials focused on orphan diseases such as cystic fibrosis, Duchenne muscular dystrophy, and other rare genetic conditions. These trials often test gene therapies, CRISPR-based gene editing, and experimental drugs designed to address the underlying causes of these conditions.
Clinical trials in Boston adhere to rigorous guidelines and regulations to ensure participant safety, ethical conduct, and scientific integrity. These trials must comply with federal standards set by the FDA and HHS, as well as the Common Rule for human research ethics. Institutions conducting clinical trials must have Institutional Review Boards (IRBs) that review and approve research protocols to ensure they prioritize participant rights and safety. Additionally, the informed consent process ensures that participants fully understand the risks and benefits before enrolling.
Massachusetts also enforces strict state-specific regulations, particularly through the Department of Public Health (DPH) and HIPAA guidelines for patient privacy. Researchers in Boston follow Good Clinical Practice (GCP) standards, and all clinical trials are required to register on ClinicalTrials.gov for transparency.
Participating in a clinical trial offers a unique chance to access cutting-edge treatments and therapies before they are widely available. During a clinical trial, participants benefit from expert care provided by top healthcare professionals, ensuring personalized attention and thorough monitoring throughout the study.
Clinical trial participation plays a crucial role in advancing medical research, often leading to groundbreaking discoveries in treatment and prevention. By joining a trial, individuals make a meaningful contribution to the development of new medical knowledge, ultimately improving future healthcare for others.
Worried about the risks of participating in a clinical trial? Read our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
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