Paid Clinical Trials Boston
Discover 2,973 paid clinical trials in Boston, Massachusetts. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)
Sponsor:
AbbVie
Location:
Code:
NCT04064827
Conditions
Chronic Kidney Disease (CKD)
Secondary Hyperparathyroidism (SHPT)
Eligibility Criteria
Sex: All
Age: 0 - 9
Healthy Volunteers: Not accepted
Interventions
Paricalcitol
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia
Sponsor:
Leigh R. Hochberg, MD, PhD.
Location:
Code:
NCT05724173
Conditions
Anarthria
Dysarthria
Tetraplegia
Spinal Cord Injuries
Amyotrophic Lateral Sclerosis
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
BrainGate Neural Interface System
Phase 1 Study of RBN-2397, an Oral PARP7 Inhibitor, in Patients With Solid Tumors
Sponsor:
Ribon Therapeutics, Inc.
Location:
Code:
NCT04053673
Conditions
Solid Tumor, Adult
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
RBN-2397
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
Sponsor:
Edwards Lifesciences
Location:
Code:
NCT05172973
Conditions
Aortic Valve Insufficiency
Aortic Valve Stenosis
Eligibility Criteria
Sex: All
Age: 0 - 70+
Healthy Volunteers: Not accepted
Interventions
SAPIEN X4 THV
Individualized Functional Connectivity Targeting in AiTBS for Depression
Sponsor:
Brigham and Women's Hospital
Location:
Code:
NCT05680727
Conditions
Depressive Disorder, Major
Depression
Mood Disorders
Mental Disorder
Psychiatric Disorder
Eligibility Criteria
Sex: All
Age: 22 - 70+
Healthy Volunteers: Not accepted
Interventions
transcranial magnetic stimulation
GaitBetter: Motor and Cognitive Training for Gait Rehabilitation and Falls Prevention in Stroke Survivors.
Sponsor:
Spaulding Rehabilitation Hospital
Location:
Code:
NCT04625127
Conditions
Stroke
Gait, Hemiplegic
Hemiplegia
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Treadmill gait training with GaitBetter
Treadmill gait training with GaitBetter + Standard of care
Standard of care
SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors
Sponsor:
American Thrombosis and Hemostasis Network
Location:
Code:
NCT04647227
Conditions
Hemophilia A With Inhibitor
Hemophilia B With Inhibitor
Eligibility Criteria
Sex: All
Age: 12 - 70+
Healthy Volunteers: Not accepted
Interventions
coagulation factor VIIa [recombinant]-jncw
Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis
Sponsor:
Kowa Research Institute, Inc.
Location:
Code:
NCT05327127
Conditions
NASH
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
K-877-ER
CSG452
Placebo
The Study Assessing the Safety and Efficacy of OK-101 Treatment in Subjects With Neuropathic Corneal Pain
Sponsor:
Okyo Pharma Ltd
Location:
Code:
NCT06637527
Conditions
Neuropathic Pain
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
OK-101 0.05%
OK-101 0.1%
Placebo
Study to Allow Patients Previously Participating in a Novartis Sponsored Trial to Continue Receiving Capmatinib Treatment as Single Agent or in Combination With Other Treatments or the Combination Treatment Alone
Sponsor:
Novartis Pharmaceuticals
Location:
Code:
NCT03040973
Conditions
Advanced Solid Tumors Which Are cMET-dependent
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Capmatinib
Nazartinib
Gefitinib
Osimertinib
With its world-renowned healthcare network and prestigious medical research institutions, Boston is a premier destination for a wide range of clinical trials. Major centers such as Massachusetts General Hospital, Brigham and Women’s Hospital, Beth Israel Deaconess Medical Center, and the Dana-Farber Cancer Institute lead groundbreaking studies across various medical fields. These institutions are at the forefront of innovation, making Boston a hub for cutting-edge clinical research.
Why choose Boston for clinical trials?
Boston stands out as a leader in healthcare and life science, and has become an important destination for participants taking part in clinical trials. With world-class medical institutions and a diverse patient population, researchers can deliver more reliable and relevant results.
The city is also home to an innovative research ecosystem, strengthened by close collaborations between hospitals, universities, and biotech companies, making it a hub for cutting-edge clinical studies.
Common conditions studied in Boston
Boston is renowned for its extensive clinical research across a wide array of medical conditions, driven by its world-class hospitals and research institutions.
Cancer
Boston's Dana-Farber Cancer Institute, Massachusetts General Hospital Cancer Center, and other top institutions are renowned for conducting cutting-edge cancer research. They lead oncology clinical trials focusing on a wide array of cancers such as breast, lung, colorectal, and melanoma.
These trials explore innovative treatments, including CAR-T cell therapy, immune checkpoint inhibitors, precision oncology, and experimental drugs designed to target specific genetic mutations in tumors.
Cardiovascular disease
Boston is a leader in cardiovascular research, addressing diseases such as coronary artery disease, heart failure, hypertension, and atrial fibrillation. Institutions like the Brigham and Women’s Hospital Heart & Vascular Center and Beth Israel Deaconess Medical Center focus on clinical trials investigating new medications, minimally invasive surgical procedures, and medical devices like left ventricular assist devices (LVADs) and transcatheter aortic valve replacements (TAVR). Studies often explore novel biomarkers for early detection and prevention strategies.
Neurological disorders
Boston's status as a hub for neuroscience research is underscored by its extensive studies into Alzheimer’s disease, Parkinson’s disease, ALS (Lou Gehrig's disease), epilepsy, and multiple sclerosis (MS).
Major hospitals such as Massachusetts General Hospital and Boston Children's Hospital lead clinical trials on disease-modifying therapies, neuroprotective agents, and gene-editing technologies. Researchers also investigate new treatments for stroke recovery and traumatic brain injuries.
Autoimmune diseases
The city’s leading research centers conduct numerous trials targeting autoimmune conditions such as rheumatoid arthritis, lupus, and Crohn's disease. These trials frequently test advanced biologic therapies, monoclonal antibodies, and small molecule drugs designed to dampen the immune response or reset immune system function. Personalized approaches like precision immunotherapy and the use of stem cells are also areas of active exploration in Boston.
Diabetes and endocrine disorders
Boston has long been at the forefront of diabetes research, with a particular focus on innovative treatments for both Type 1 and Type 2 diabetes. Trials often explore new forms of insulin, artificial pancreas technologies, continuous glucose monitors, and regenerative medicine approaches like beta-cell transplantation. Endocrine research also spans conditions such as thyroid disorders, obesity, and metabolic syndrome.
Rare diseases
Boston’s research institutions are committed to tackling rare diseases, with several clinical trials focused on orphan diseases such as cystic fibrosis, Duchenne muscular dystrophy, and other rare genetic conditions. These trials often test gene therapies, CRISPR-based gene editing, and experimental drugs designed to address the underlying causes of these conditions.
Local regulations and guidelines
Clinical trials in Boston adhere to rigorous guidelines and regulations to ensure participant safety, ethical conduct, and scientific integrity. These trials must comply with federal standards set by the FDA and HHS, as well as the Common Rule for human research ethics. Institutions conducting clinical trials must have Institutional Review Boards (IRBs) that review and approve research protocols to ensure they prioritize participant rights and safety. Additionally, the informed consent process ensures that participants fully understand the risks and benefits before enrolling.
Massachusetts also enforces strict state-specific regulations, particularly through the Department of Public Health (DPH) and HIPAA guidelines for patient privacy. Researchers in Boston follow Good Clinical Practice (GCP) standards, and all clinical trials are required to register on ClinicalTrials.gov for transparency.
Benefits of participating in clinical trials
Participating in a clinical trial offers a unique chance to access cutting-edge treatments and therapies before they are widely available. During a clinical trial, participants benefit from expert care provided by top healthcare professionals, ensuring personalized attention and thorough monitoring throughout the study.
Clinical trial participation plays a crucial role in advancing medical research, often leading to groundbreaking discoveries in treatment and prevention. By joining a trial, individuals make a meaningful contribution to the development of new medical knowledge, ultimately improving future healthcare for others.
Worried about the risks of participating in a clinical trial? Read our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
How to enroll in a clinical trial in Boston
Enrolling in a clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:
- Identify your trial: Use our intuitive search bar or filter options to locate clinical trials specific to requirements. This first step simplifies the process of finding relevant research studies tailored to your needs.
- Select your preferred location: To find trials conveniently located near you, simply input your preferred location into the dedicated filter bar on the left-hand side of the page.
- Explore study details: For in-depth information about each study, simply click the “Learn More” button. This will provide you with comprehensive details about the trial, including objectives, procedures, and eligibility criteria.
- Complete the health profile: After clicking on the “Get started” button you will be taken to our efficient 5-step application process to provide important health information. This helps us match you with the clinical trial that best fits your needs.
- Submit the application: After completing the application, send it in. A clinical trial coordinator will review it and contact you regarding the possibility of participation.