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Paid Clinical Trials North Carolina

Discover 2,437 paid clinical trials in North Carolina. Search by city or condition to find a research study near you that matches your needs across various therapeutic areas.

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A Study of NVL-655 in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

Recruiting
PHASE1
PHASE2

Sponsor:

Nuvalent Inc.

Location:

Durham, Washington, Atlanta, Baltimoreshow 19 more

Code:

NCT05384626

Conditions

Locally Advanced Solid Tumor

Metastatic Solid Tumor

Eligibility Criteria

Sex: All

Age: 12+

Healthy Volunteers: Not accepted

Interventions

NVL-655

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

Recruiting

Sponsor:

Pfizer

Location:

Chapel Hill, Snellville, Chevy Chase, Glen Burnieshow 10 more

Code:

NCT06398626

Conditions

Colitis, Ulcerative

Eligibility Criteria

Sex: All

Age: 18 - 64

Healthy Volunteers: Not accepted

Interventions

Etrasimod

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

Recruiting
PHASE1
PHASE2

Sponsor:

Aulos Bioscience, Inc.

Location:

Huntersville, Nashville, Grand Rapids, Houstonshow 2 more

Code:

NCT05267626

Conditions

Advanced Solid Tumor

Metastatic Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

AU-007

Aldesleukin

Avelumab

Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

Recruiting
PHASE3

Sponsor:

GB002, Inc.

Location:

Chapel Hill, Durham, Richmond, Charlestonshow 47 more

Code:

NCT05934526

Conditions

Pulmonary Arterial Hypertension

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Placebo

Seralutinib

Generic Dry Powder Inhaler

Primary Subtalar Arthrodesis for Calcaneal Fractures

Recruiting

Sponsor:

Wake Forest University Health Sciences

Location:

Winston-Salem, Concord, Chapel Hill, Charlotteshow 9 more

Code:

NCT06249126

Conditions

Calcaneus Fracture

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA)

Open Reduction Internal Fixation (ORIF) only

Study to Assess the Safety and Efficacy of OCU410ST for Stargardt Disease

Recruiting
PHASE1
PHASE2

Sponsor:

Ocugen

Location:

Durham, Jackson, Miami, Dallasshow 2 more

Code:

NCT05956626

Conditions

Stargardt Disease

Eligibility Criteria

Sex: All

Age: 6 - 65

Healthy Volunteers: Not accepted

Interventions

OCU410ST

Reparixin in Patients with Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

Recruiting
PHASE2

Sponsor:

Icahn School of Medicine at Mount Sinai

Location:

Winston-Salem, New York, Buffalo

Code:

NCT05835466

Conditions

Myelofibrosis (PMF)

Post Essential Thrombocythemia Myelofibrosis (ET-MF)

Post Polycythemia Vera Related Myelofibrosis (PV-MF)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

reparixin

Rare and Atypical Diabetes Network

Recruiting

Sponsor:

University of South Florida

Location:

Chapel Hill, Baltimore, Nashville, Indianapolisshow 9 more

Code:

NCT05544266

Conditions

Diabetes Mellitus

Diabetes Mellitus Progression

Glucose Intolerance

Glucose Metabolism Disorders

Metabolic Disease

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy

Recruiting
PHASE2
PHASE3

Sponsor:

Biohaven Therapeutics Ltd.

Location:

Chapel Hill, Charleston, McLean, Washingtonshow 27 more

Code:

NCT06309966

Conditions

Focal Epilepsy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

BHV-7000

Placebo

Neoadjuvant Chemotherapy for Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Recruiting
PHASE2

Sponsor:

Wake Forest University Health Sciences

Location:

Winston-Salem

Code:

NCT05825066

Conditions

Pancreas Adenocarcinoma

Borderline Resectable Pancreatic Adenocarcinoma

Locally Advanced Pancreatic Adenocarcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Nab paclitaxel

Gemcitabine

Radiological Assessments

mFOLFIRINOX

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