Find clinical trials for Lymphoma. Search for oncology clinical trials in different cities and states across the United States.
Sponsor:
Sidney Kimmel Cancer Center at Thomas Jefferson University
Location:
Code:
NCT03198026
Conditions
Non-Hodgkin's Lymphoma
Ann Arbor Stage II Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue
Ann Arbor Stage II Follicular Lymphoma
Ann Arbor Stage II Nodal Marginal Zone Lymphoma
Ann Abor Stage III B-Cell Non-Hodgkin Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Ibrutinib
Obinutuzumab
Laboratory Biomarker Analysis
Sponsor:
Nuvalent Inc.
Location:
Code:
NCT05384626
Conditions
Locally Advanced Solid Tumor
Metastatic Solid Tumor
Eligibility Criteria
Sex: All
Age: 12+
Healthy Volunteers: Not accepted
Interventions
NVL-655
Sponsor:
Memorial Sloan Kettering Cancer Center
Location:
Code:
NCT02315326
Conditions
Adult Patients With Newly Diagnosed or Relapsed or Refractory Primary Central Nervous System Lymphoma (PCNSL)
Or Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Ibrutinib
HD- Methotrexate (MTX)
Rituximab + HD- Methotrexate (MTX)
procarbazine
Sponsor:
National Cancer Institute (NCI)
Location:
Code:
NCT02203526
Conditions
Primary Central Nervous System Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Isavuconazole
TEDDI
Rituximab
Cytarabine
TEDD
Sponsor:
University of Utah
Location:
Code:
NCT06227026
Conditions
Acute Lymphoblastic Leukemia
Diffuse Large B Cell Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Anti-CD19 CAR-T cells
Sponsor:
M.D. Anderson Cancer Center
Location:
Code:
NCT00501826
Conditions
T Acute Lymphoblastic Leukemia
T Lymphoblastic Lymphoma
Eligibility Criteria
Sex: All
Age: 0 - 70+
Healthy Volunteers: Not accepted
Interventions
Cyclophosphamide
Cytarabine
Dexamethasone
Doxorubicin Hydrochloride
Mercaptopurine
Sponsor:
Memorial Sloan Kettering Cancer Center
Location:
Code:
NCT06377566
Conditions
Hodgkin Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Brentuximab vedotin
Doxorubicin
Vinblastine
Dacarbazine
Pembrolizumab
Sponsor:
Nurix Therapeutics, Inc.
Location:
Code:
NCT05107674
Conditions
Ovarian Cancer, Epithelial
Gastric Cancer
GastroEsophageal Junction (GEJ) Cancer
Head and Neck Squamous Cell Carcinoma
Metastatic or Unresectable Melanoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
NX-1607
Paclitaxel
Sponsor:
City of Hope Medical Center
Location:
Code:
NCT04670874
Conditions
Cutaneous Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Quality-of-Life Assessment
Questionnaire Administration
Sponsor:
Virginia Commonwealth University
Location:
Code:
NCT06439420
Conditions
Primary Brain Tumor
Glioblastoma
Astrocytoma
Oligodendroglioma
Meningioma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Cognitive Behavioral Therapy for Insomnia
Clinical trials for lymphoma are research studies used to evaluate new treatments, therapies, or diagnostic methods for lymphoma, a type of cancer that affects the lymphatic system. These trials aim to discover more effective ways to manage lymphoma, improve patient outcomes, and enhance survival rates. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.
As the sixth most common form of cancer, clinical research is vital. Clinical trials for lymphoma are important for advancing the development of new and potentially more effective treatments, improving understanding of the disease, and enhancing patient care. By testing innovative therapies, combinations of existing treatments, and new approaches, trials help identify better ways to manage lymphoma, reduce side effects, and improve survival rates.
Interested in discovering the significance of clinical trials for cancer? Read about their role in developing new treatments, improving patient outcomes, and advancing cancer research in our detailed guide.
There are several different types of clinical trials available to researchers when designing a lymphoma clinical study. Depending on the objectives of the trial, researchers may choose one of the following methods.
Diagnostic trials in lymphoma clinical research focus on developing and evaluating new methods or tools for detecting and diagnosing the disease earlier and more precisely. These trials test innovative diagnostic techniques, such as advanced imaging technologies, blood tests, or genetic assays, to improve the precision of lymphoma diagnosis and monitoring.
Interventional trials for lymphoma actively test new treatments or therapeutic approaches by administering experimental drugs, therapies, or procedures to participants. These trials aim to evaluate the effectiveness and safety of innovative treatments, such as novel chemotherapy agents, targeted therapies, or immunotherapies. Researchers may also compare them to standard treatments or placebos.
Pharmacokinetic and pharmacodynamic studies in lymphoma patients are designed to gain a comprehensive understanding of how drugs are absorbed, distributed, metabolized, and excreted in the body, and how these processes influence the drug's therapeutic and adverse effects.
These studies are essential for optimizing treatment regimens by determining the most effective and safe dosages and administration schedules. By examining factors such as the rate and extent of drug absorption, the distribution within various tissues, the metabolic pathways involved, and the routes of excretion, researchers can design treatments to maximize efficacy while minimizing toxicity.
Researchers studying lymphoma can also use observational trials to monitor and analyze patients without administering experimental treatments. These trials collect data on disease progression, treatment outcomes, and patient responses to standard therapies or existing interventions.
These trials focus on understanding the natural history of lymphoma, identifying patterns and risk factors, and assessing the effectiveness of current treatments in real-world settings. Observing patients over time means researchers can gain valuable insights into disease behavior and treatment efficacy, which can inform future clinical trials and help improve overall patient care.
There are several reasons why someone should consider participating in a clinical trial for lymphoma. Taking part can offer significant benefits for participants, but that doesn’t mean there aren’t risks to consider too.
Participating in a clinical trial for lymphoma offers several benefits, including access to cutting-edge treatments and therapies that may not yet be available to the wider public. During the trial, participants receive close monitoring and care from specialized medical teams, which can lead to early detection of side effects and more tailored treatment adjustments.
Another key benefit of getting involved is that participants have the opportunity to contribute to valuable research that advances medical knowledge and helps develop better future treatments. Additionally, involvement in a lymphoma clinical trial provides the opportunity to benefit from innovative interventions that could improve outcomes and quality of life.
There are a number of risks and considerations for participants getting involved in a clinical trial for lymphoma. The main risk is the potential for experiencing unknown side effects or adverse reactions from experimental treatments, which may differ from standard therapies. There is also the possibility that the new treatment may not be effective or make the condition worse.
Participants might need to adhere to a strict schedule for medical visits, tests, and treatment regimens, which can be time consuming and impact their schedule. Additionally, there may be uncertainties about the coverage of trial-related expenses, as well as the emotional stress associated with navigating experimental therapies.
Eligibility for participating in a clinical trial for lymphoma typically includes individuals diagnosed with lymphoma, ranging from early-stage to advanced disease, depending on the trial's focus. Some trials may target specific types of lymphoma, such as Hodgkin or non-Hodgkin lymphoma, or particular patient groups based on factors like age, genetic mutations, or previous treatments.
Researchers use a thorough screening process to determine whether participants meet the criteria and can safely receive the experimental interventions. Other eligibility criteria may also include age, gender, health status, severity of the disease, or previous treatments for lymphoma.
If enrolled, and depending on the study type, you may receive an experimental treatment, placebo, or standard care, and will be closely monitored through regular medical visits, tests, and assessments to evaluate the treatment's effectiveness and safety.
The trial may also involve additional support and resources, and while the outcomes are uncertain, participants have the opportunity to access innovative therapies and contribute to advancing medical research.
Enrolling in a clinical trial studying lymphoma through our platform is a straightforward and user-friendly process. Here's how to get started: