Find clinical trials for Lymphoma. Search for Lymphoma clinical trials in different cities and states across the United States.
Sponsor:
SciTech Development, LLC
Location:
Code:
NCT04234048
Conditions
T-cell Lymphoma
Cutaneous/Peripheral T-Cell Lymphoma
Peripheral T-cell Lymphoma
Peripheral T-Cell Lymphoma, Not Classified
Primary Cutaneous T-cell Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Fenretinide
Sponsor:
Canadian Cancer Trials Group
Location:
Code:
NCT04161248
Conditions
Lymphoma, B-Cell
Eligibility Criteria
Sex: All
Age: 16 - 65
Healthy Volunteers: Not accepted
Interventions
Venetoclax
Rituximab Injection
Rituximab SC
Gemcitabine
Dexamethasone
Sponsor:
UNC Lineberger Comprehensive Cancer Center
Location:
Code:
NCT04548648
Conditions
Central Nervous System Lymphoma
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Acalabrutinib
Isavuconazole
Sponsor:
St. Jude Children's Research Hospital
Location:
Code:
NCT05550948
Conditions
ALL
Hodgkin Lymphoma
Cancer
Survivorship
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Transcranial photobiomodulation (tPBM) - Mobile System
Sponsor:
Jiangsu Simcere Pharmaceutical Co., Ltd.
Location:
Code:
NCT05569057
Conditions
Advanced Solid Tumor
Cutaneous T-cell Lymphoma (CTCL)
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
SIM1811-03
Sponsor:
Genmab
Location:
Code:
NCT05206357
Conditions
Non-hodgkin Lymphoma
Eligibility Criteria
Sex: All
Age: 1 - 25
Healthy Volunteers: Not accepted
Interventions
Epcoritamab
Sponsor:
Academic and Community Cancer Research United
Location:
Code:
NCT06238648
Conditions
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Primary Mediastinal Large B-Cell Lymphoma
Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biopsy
Biospecimen Collection
Computed Tomography
Epcoritamab
Magnetic Resonance Imaging
Sponsor:
Lazaros Lekakis
Location:
Code:
NCT05260957
Conditions
Refractory Non-Hodgkin Lymphoma
Relapsed Non Hodgkin Lymphoma
Aggressive Non-Hodgkin Lymphoma
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Mosunetuzumab
Polatuzumab
CAR-T Cell Therapy
Sponsor:
M.D. Anderson Cancer Center
Location:
Code:
NCT01371630
Conditions
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
Burkitt-Like Lymphoma With 11q Aberration
High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements
High Grade B-Cell Lymphoma, Not Otherwise Specified
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Blinatumomab
Cyclophosphamide
Cytarabine
Dexamethasone
Inotuzumab Ozogamicin
Sponsor:
ImmunityBio, Inc.
Location:
Code:
NCT05618925
Conditions
Non Hodgkin's Lymphoma Refractory/Relapsed
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
N803
CD19t-haNK suspension
Cyclophosphamide
Fludarabine
Rituximab
Clinical trials for lymphoma are research studies used to evaluate new treatments, therapies, or diagnostic methods for lymphoma, a type of cancer that affects the lymphatic system. These trials aim to discover more effective ways to manage lymphoma, improve patient outcomes, and enhance survival rates. They may involve testing new drugs, combinations of existing treatments, targeted therapies, immunotherapies, or novel approaches like gene therapy.
As the sixth most common form of cancer, clinical research is vital. Clinical trials for lymphoma are important for advancing the development of new and potentially more effective treatments, improving understanding of the disease, and enhancing patient care. By testing innovative therapies, combinations of existing treatments, and new approaches, trials help identify better ways to manage lymphoma, reduce side effects, and improve survival rates.
Interested in discovering the significance of clinical trials for cancer? Read about their role in developing new treatments, improving patient outcomes, and advancing cancer research in our detailed guide.
There are several different types of clinical trials available to researchers when designing a lymphoma clinical study. Depending on the objectives of the trial, researchers may choose one of the following methods.
Diagnostic trials in lymphoma clinical research focus on developing and evaluating new methods or tools for detecting and diagnosing the disease earlier and more precisely. These trials test innovative diagnostic techniques, such as advanced imaging technologies, blood tests, or genetic assays, to improve the precision of lymphoma diagnosis and monitoring.
Interventional trials for lymphoma actively test new treatments or therapeutic approaches by administering experimental drugs, therapies, or procedures to participants. These trials aim to evaluate the effectiveness and safety of innovative treatments, such as novel chemotherapy agents, targeted therapies, or immunotherapies. Researchers may also compare them to standard treatments or placebos.
Pharmacokinetic and pharmacodynamic studies in lymphoma patients are designed to gain a comprehensive understanding of how drugs are absorbed, distributed, metabolized, and excreted in the body, and how these processes influence the drug's therapeutic and adverse effects.
These studies are essential for optimizing treatment regimens by determining the most effective and safe dosages and administration schedules. By examining factors such as the rate and extent of drug absorption, the distribution within various tissues, the metabolic pathways involved, and the routes of excretion, researchers can design treatments to maximize efficacy while minimizing toxicity.
Researchers studying lymphoma can also use observational trials to monitor and analyze patients without administering experimental treatments. These trials collect data on disease progression, treatment outcomes, and patient responses to standard therapies or existing interventions.
These trials focus on understanding the natural history of lymphoma, identifying patterns and risk factors, and assessing the effectiveness of current treatments in real-world settings. Observing patients over time means researchers can gain valuable insights into disease behavior and treatment efficacy, which can inform future clinical trials and help improve overall patient care.
There are several reasons why someone should consider participating in a clinical trial for lymphoma. Taking part can offer significant benefits for participants, but that doesn’t mean there aren’t risks to consider too.
Participating in a clinical trial for lymphoma offers several benefits, including access to cutting-edge treatments and therapies that may not yet be available to the wider public. During the trial, participants receive close monitoring and care from specialized medical teams, which can lead to early detection of side effects and more tailored treatment adjustments.
Another key benefit of getting involved is that participants have the opportunity to contribute to valuable research that advances medical knowledge and helps develop better future treatments. Additionally, involvement in a lymphoma clinical trial provides the opportunity to benefit from innovative interventions that could improve outcomes and quality of life.
There are a number of risks and considerations for participants getting involved in a clinical trial for lymphoma. The main risk is the potential for experiencing unknown side effects or adverse reactions from experimental treatments, which may differ from standard therapies. There is also the possibility that the new treatment may not be effective or make the condition worse.
Participants might need to adhere to a strict schedule for medical visits, tests, and treatment regimens, which can be time consuming and impact their schedule. Additionally, there may be uncertainties about the coverage of trial-related expenses, as well as the emotional stress associated with navigating experimental therapies.
Eligibility for participating in a clinical trial for lymphoma typically includes individuals diagnosed with lymphoma, ranging from early-stage to advanced disease, depending on the trial's focus. Some trials may target specific types of lymphoma, such as Hodgkin or non-Hodgkin lymphoma, or particular patient groups based on factors like age, genetic mutations, or previous treatments.
Researchers use a thorough screening process to determine whether participants meet the criteria and can safely receive the experimental interventions. Other eligibility criteria may also include age, gender, health status, severity of the disease, or previous treatments for lymphoma.
If enrolled, and depending on the study type, you may receive an experimental treatment, placebo, or standard care, and will be closely monitored through regular medical visits, tests, and assessments to evaluate the treatment's effectiveness and safety.
The trial may also involve additional support and resources, and while the outcomes are uncertain, participants have the opportunity to access innovative therapies and contribute to advancing medical research.
Enrolling in a clinical trial studying lymphoma through our platform is a straightforward and user-friendly process. Here's how to get started: