Clinical Trials In Springfield

Discover hundreds of clinical trials in Springfield.
Search clinical trials in Springfield by condition or phase.

e.g. Respiratory Diseases

Springfield•Healthy volunteers: No

Filter results

Results: 172

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

Recruiting

Phase 3

Sponsor:

Sanofi

Location:

Springfield, Saint Louis, Ozark, Birminghamshow 61 more

Code:

NCT06141473

Conditions

Multiple Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Not accepted

Interventions

Frexalimab

Teriflunomide

Placebo infusion

Placebo tablet

MRI contrast-enhancing agents

MILD® Percutaneous Image-Guided Lumbar Decompression: a Medicare Claims Study

Recruiting

Sponsor:

Vertos Medical, Inc.

Location:

Springfield, West Plains, Washington, Troyshow 941 more

Code:

NCT03072927

Conditions

Lumbar Spinal Stenosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MILD

Interspinous Process Decompression

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

Recruiting

Phase 2

Sponsor:

Janssen Research & Development, LLC

Location:

Springfield, Chandler, Duarte, Fullertonshow 24 more

Code:

NCT06120140

Conditions

Carcinoma, Non-Small-Cell Lung

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Amivantamab

Lazertinib

Doxycycline

Minocycline

Clindamycin

A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain

Recruiting

Phase 2

Sponsor:

Eli Lilly and Company

Location:

Springfield, Saint Peters, Kansas City, Chandlershow 29 more

Code:

NCT06074562

Conditions

Diabetic Peripheral Neuropathy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

LY3556050

Placebo

Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial

Recruiting

Sponsor:

Wake Forest University Health Sciences

Location:

Springfield, Saint Louis, Rolla, Osage Beachshow 187 more

Code:

NCT06216574

Conditions

Breast Cancer Female

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Internet-based Intervention

Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients

Recruiting

Phase 2

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Sunset Hills, Sullivan, Sainte Genevieveshow 95 more

Code:

NCT04310020

Conditions

Recurrent Lung Non-Small Cell Carcinoma

Stage II Lung Cancer AJCC v8

Stage III Lung Cancer AJCC v8

Unresectable Lung Non-Small Cell Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Atezolizumab

Biospecimen Collection

Computed Tomography

Hypofractionated Radiation Therapy

Magnetic Resonance Imaging

Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment

Recruiting

Phase 3

Sponsor:

Boehringer Ingelheim

Location:

Springfield, Bridgeton, Huntsville, Bullhead Cityshow 10 more

Code:

NCT06151574

Conditions

Lung Cancer, Non-squamous, Non-small Cell

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

zongertinib

pembrolizumab

cisplatin

carboplatin

pemetrexed

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

Recruiting

Phase 3

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Washington, Saint Peters, Saint Louisshow 139 more

Code:

NCT04530565

Conditions

B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Blinatumomab

Bone Marrow Aspiration and Biopsy

Cyclophosphamide

Cytarabine

Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors

Recruiting

Phase 3

Sponsor:

University of Rochester NCORP Research Base

Location:

Springfield, Washington, Sunset Hills, Sullivanshow 270 more

Code:

NCT03996265

Conditions

Be Diagnosed With Cancer and Have Completed Systemic Therapy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Bupropion Hydrochloride Controlled-release

Placebo Administration

Quality-of-Life Assessment

Questionnaire Administration

The PEERLESS II Study

Recruiting

Sponsor:

Inari Medical

Location:

Springfield, Kansas City, Birmingham, Pasadenashow 45 more

Code:

NCT06055920

Conditions

Pulmonary Embolism

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

FlowTriever System

Anticoagulation Agents

e.g. Respiratory Diseases

Springfield•Healthy volunteers: No

Filter results

Results: 172

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

Recruiting

Phase 3

Sponsor:

Sanofi

Location:

Springfield, Saint Louis, Ozark, Birminghamshow 61 more

Code:

NCT06141473

Conditions

Multiple Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Not accepted

Interventions

Frexalimab

Teriflunomide

Placebo infusion

Placebo tablet

MRI contrast-enhancing agents

MILD® Percutaneous Image-Guided Lumbar Decompression: a Medicare Claims Study

Recruiting

Sponsor:

Vertos Medical, Inc.

Location:

Springfield, West Plains, Washington, Troyshow 941 more

Code:

NCT03072927

Conditions

Lumbar Spinal Stenosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MILD

Interspinous Process Decompression

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

Recruiting

Phase 2

Sponsor:

Janssen Research & Development, LLC

Location:

Springfield, Chandler, Duarte, Fullertonshow 24 more

Code:

NCT06120140

Conditions

Carcinoma, Non-Small-Cell Lung

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Amivantamab

Lazertinib

Doxycycline

Minocycline

Clindamycin

A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain

Recruiting

Phase 2

Sponsor:

Eli Lilly and Company

Location:

Springfield, Saint Peters, Kansas City, Chandlershow 29 more

Code:

NCT06074562

Conditions

Diabetic Peripheral Neuropathy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

LY3556050

Placebo

Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial

Recruiting

Sponsor:

Wake Forest University Health Sciences

Location:

Springfield, Saint Louis, Rolla, Osage Beachshow 187 more

Code:

NCT06216574

Conditions

Breast Cancer Female

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Internet-based Intervention

Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients

Recruiting

Phase 2

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Sunset Hills, Sullivan, Sainte Genevieveshow 95 more

Code:

NCT04310020

Conditions

Recurrent Lung Non-Small Cell Carcinoma

Stage II Lung Cancer AJCC v8

Stage III Lung Cancer AJCC v8

Unresectable Lung Non-Small Cell Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Atezolizumab

Biospecimen Collection

Computed Tomography

Hypofractionated Radiation Therapy

Magnetic Resonance Imaging

Beamion LUNG-2: A Study to Test Whether Zongertinib (BI 1810631) Helps People With Advanced Non-small Cell Lung Cancer With HER2 Mutations Compared With Standard Treatment

Recruiting

Phase 3

Sponsor:

Boehringer Ingelheim

Location:

Springfield, Bridgeton, Huntsville, Bullhead Cityshow 10 more

Code:

NCT06151574

Conditions

Lung Cancer, Non-squamous, Non-small Cell

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

zongertinib

pembrolizumab

cisplatin

carboplatin

pemetrexed

Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

Recruiting

Phase 3

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Washington, Saint Peters, Saint Louisshow 139 more

Code:

NCT04530565

Conditions

B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Blinatumomab

Bone Marrow Aspiration and Biopsy

Cyclophosphamide

Cytarabine

Bupropion to Reduce Cancer Related Fatigue in Cancer Survivors

Recruiting

Phase 3

Sponsor:

University of Rochester NCORP Research Base

Location:

Springfield, Washington, Sunset Hills, Sullivanshow 270 more

Code:

NCT03996265

Conditions

Be Diagnosed With Cancer and Have Completed Systemic Therapy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Bupropion Hydrochloride Controlled-release

Placebo Administration

Quality-of-Life Assessment

Questionnaire Administration

The PEERLESS II Study

Recruiting

Sponsor:

Inari Medical

Location:

Springfield, Kansas City, Birmingham, Pasadenashow 45 more

Code:

NCT06055920

Conditions

Pulmonary Embolism

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

FlowTriever System

Anticoagulation Agents