Clinical Trials In Springfield

Discover hundreds of clinical trials in Springfield.
Search clinical trials in Springfield by condition or phase.

e.g. Respiratory Diseases

Springfield•Healthy volunteers: No

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Results: 169

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Bolivar, Branson, Joplinshow 351 more

Code:

NCT03866382

Conditions

Bladder Adenocarcinoma

Bladder Clear Cell Adenocarcinoma

Bladder Mixed Adenocarcinoma

Bladder Neuroendocrine Carcinoma

Bladder Small Cell Neuroendocrine Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Bone Scan

Cabozantinib S-malate

Computed Tomography

Echocardiography

The PEERLESS II Study

Recruiting

Sponsor:

Inari Medical

Location:

Springfield, Kansas City, Omaha, Planoshow 47 more

Code:

NCT06055920

Conditions

Pulmonary Embolism

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

FlowTriever System

Anticoagulation Agents

Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Rolla, Sullivan, Farmingtonshow 95 more

Code:

NCT04310020

Conditions

Recurrent Lung Non-Small Cell Carcinoma

Stage II Lung Cancer AJCC v8

Stage III Lung Cancer AJCC v8

Unresectable Lung Non-Small Cell Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Atezolizumab

Biospecimen Collection

Computed Tomography

Hypofractionated Radiation Therapy

Magnetic Resonance Imaging

Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Bolivar, Branson, Joplinshow 244 more

Code:

NCT04164082

Conditions

Bladder Urothelial Carcinoma In Situ

Non-Muscle Invasive Bladder Urothelial Carcinoma

Stage 0a Bladder Cancer AJCC v8

Stage 0is Bladder Cancer AJCC v8

Stage I Bladder Cancer AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biopsy

Biospecimen Collection

Computed Tomography

Cystoscopy

Gemcitabine Hydrochloride

Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Chemotherapy

Recruiting

PHASE3

Sponsor:

University of Rochester NCORP Research Base

Location:

Springfield, Joplin, Fort Smith, Ballwinshow 77 more

Code:

NCT04829539

Conditions

Hematopoietic and Lymphoid Cell Neoplasm

Malignant Solid Neoplasm

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Behavioral Intervention

Quality-of-Life Assessment

Questionnaire Administration

S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

Recruiting

PHASE3

Sponsor:

SWOG Cancer Research Network

Location:

Springfield, Bolivar, Branson, Joplinshow 499 more

Code:

NCT04071457

Conditions

Multiple Myeloma

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Lenalidomide

Daratumumab/rHuPH20

Reaching Rural Cancer Survivors Who Smoke Using Text-Based Program

Recruiting

PHASE3

Sponsor:

Alliance for Clinical Trials in Oncology

Location:

Springfield, Osage Beach, Rolla, Sullivanshow 148 more

Code:

NCT05008848

Conditions

Cigarette Smoking-Related Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Smoking Cessation Intervention

Health Promotion and Education

Informational Intervention

Questionnaire Administration

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-Small Cell Lung Cancer, ALCHEMIST Trial

Recruiting

PHASE3

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Bolivar, Branson, Joplinshow 684 more

Code:

NCT04267848

Conditions

Lung Non-Small Cell Carcinoma

Lung Non-Small Cell Squamous Carcinoma

Lung Non-Squamous Non-Small Cell Carcinoma

Stage II Lung Cancer AJCC v8

Stage IIIA Lung Cancer AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Carboplatin

Cisplatin

Computed Tomography

Echocardiography

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

Recruiting

PHASE3

Sponsor:

SWOG Cancer Research Network

Location:

Springfield, Joplin, Rolla, Columbiashow 238 more

Code:

NCT03678025

Conditions

Castration Levels of Testosterone

Metastatic Prostatic Adenocarcinoma

Stage IV Prostate Cancer AJCC v8

Stage IVA Prostate Cancer AJCC v8

Stage IVB Prostate Cancer AJCC v8

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Abiraterone

Bicalutamide

Degarelix

Docetaxel

Flutamide

Testing the Addition of Trastuzumab or Trastuzumab/Pertuzumab to the Usual Chemotherapy for HER2 Positive Endometrial Cancer

Recruiting

PHASE2

PHASE3

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Rolla, Columbia, Tulsashow 272 more

Code:

NCT05256225

Conditions

Endometrial Carcinoma

Endometrial Clear Cell Adenocarcinoma

Endometrial Dedifferentiated Carcinoma

Endometrial Endometrioid Adenocarcinoma

Endometrial Mixed Cell Adenocarcinoma

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Carboplatin

Computed Tomography

Echocardiography

High-Dose-Rate Vaginal Cuff Brachytherapy