Paid Clinical Trials Springfield

Discover 183 paid clinical trials in Springfield. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Results: 183

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Recruiting

PHASE3

Sponsor:

NRG Oncology

Location:

Springfield, Bolivar, Branson, Joplinshow 638 more

Code:

NCT05879926

Conditions

Breast Cancer

Eligibility Criteria

Sex: Female

Age: 18 - 60

Healthy Volunteers: Not accepted

Interventions

Ovarian Function Suppression + Aromatase Inhibitor

Adjuvant Chemotherapy + Ovarian Function Suppression

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Bolivar, Branson, Joplinshow 351 more

Code:

NCT03866382

Conditions

Bladder Adenocarcinoma

Bladder Clear Cell Adenocarcinoma

Bladder Mixed Adenocarcinoma

Bladder Neuroendocrine Carcinoma

Bladder Small Cell Neuroendocrine Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Bone Scan

Cabozantinib S-malate

Computed Tomography

Echocardiography

Testing the Addition of an Anti-cancer Drug, Pembrolizumab, to the Usual Intravesical Chemotherapy Treatment (Gemcitabine) for the Treatment of BCG-Unresponsive Non-muscle Invasive Bladder Cancer

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Bolivar, Branson, Joplinshow 244 more

Code:

NCT04164082

Conditions

Bladder Urothelial Carcinoma In Situ

Non-Muscle Invasive Bladder Urothelial Carcinoma

Stage 0a Bladder Cancer AJCC v8

Stage 0is Bladder Cancer AJCC v8

Stage I Bladder Cancer AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biopsy

Biospecimen Collection

Computed Tomography

Cystoscopy

Gemcitabine Hydrochloride

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Recruiting

PHASE3

Sponsor:

AbbVie

Location:

Springfield, Kansas City, Jonesboro, Oklahoma Cityshow 74 more

Code:

NCT05814627

Conditions

Rheumatoid Arthritis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Upadacitinib

Adalimumab

Upadacitinib Matching Placebo

Adalimumab Matching Placebo

MILD® Percutaneous Image-Guided Lumbar Decompression: a Medicare Claims Study

Recruiting

Sponsor:

Vertos Medical, Inc.

Location:

Springfield, Bolivar, Carthage, Rogersshow 944 more

Code:

NCT03072927

Conditions

Lumbar Spinal Stenosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MILD

Interspinous Process Decompression

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Recruiting

PHASE3

Sponsor:

NRG Oncology

Location:

Springfield, Little Rock, Saint Peters, Creve Coeurshow 72 more

Code:

NCT03801876

Conditions

Clinical Stage I Esophageal Adenocarcinoma AJCC v8

Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8

Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8

Clinical Stage II Esophageal Adenocarcinoma AJCC v8

Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Carboplatin

Esophagectomy

Intensity-Modulated Radiation Therapy

Paclitaxel

Proton Beam Radiation Therapy

Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients

Recruiting

PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Springfield, Rolla, Sullivan, Farmingtonshow 95 more

Code:

NCT04310020

Conditions

Recurrent Lung Non-Small Cell Carcinoma

Stage II Lung Cancer AJCC v8

Stage III Lung Cancer AJCC v8

Unresectable Lung Non-Small Cell Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Atezolizumab

Biospecimen Collection

Computed Tomography

Hypofractionated Radiation Therapy

Magnetic Resonance Imaging

Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial

Recruiting

Sponsor:

Wake Forest University Health Sciences

Location:

Springfield, Joplin, Osage Beach, Rollashow 191 more

Code:

NCT06216574

Conditions

Breast Cancer Female

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Internet-based Intervention

A 12-Month Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

Recruiting

PHASE3

Sponsor:

Eli Lilly and Company

Location:

Springfield, Kansas City, Little Rock, Wichitashow 74 more

Code:

NCT04396574

Conditions

Migraine

Eligibility Criteria

Sex: All

Age: 6 - 17

Healthy Volunteers: Not accepted

Interventions

Lasmiditan

Testing the Addition of the Chemotherapy Drug Lomustine (Gleostine®) to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Methylated Glioblastoma

Recruiting

PHASE3

Sponsor:

NRG Oncology

Location:

Springfield, Lee's Summit, Sullivan, Overland Parkshow 249 more

Code:

NCT05095376

Conditions

Glioblastoma

Gliosarcoma

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Interventions

Lomustine

Photon Beam Radiation Therapy

Quality-of-Life Assessment

Questionnaire Administration

Temozolomide