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Paid Clinical Trials Cleveland

Discover 1,512 paid clinical trials in Cleveland, Ohio. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Recruiting

Sponsor:

Edwards Lifesciences

Location:

Cleveland, Detroit, Pittsburgh, Hamiltonshow 25 more

Code:

NCT05172973

Conditions

Aortic Valve Insufficiency

Aortic Valve Stenosis

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

SAPIEN X4 THV

SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors

Recruiting

Sponsor:

American Thrombosis and Hemostasis Network

Location:

Cleveland, Detroit, Lansing, Washingtonshow 19 more

Code:

NCT04647227

Conditions

Hemophilia A With Inhibitor

Hemophilia B With Inhibitor

Eligibility Criteria

Sex: All

Age: 12 - 70+

Healthy Volunteers: Not accepted

Interventions

coagulation factor VIIa [recombinant]-jncw

Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)

Recruiting
PHASE1
PHASE2

Sponsor:

Merck Sharp & Dohme LLC

Location:

Cleveland, Pittsburgh, Baltimore, Chicagoshow 7 more

Code:

NCT02861573

Conditions

Metastatic Castration-Resistant Prostate Cancer

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Pembrolizumab 200 mg

Olaparib 400 mg

Docetaxel 75 mg/m^2

Prednisone 5 mg

Enzalutamide 160 mg

ACP-204 in Adults With Alzheimer's Disease Psychosis

Recruiting
PHASE2
PHASE3

Sponsor:

ACADIA Pharmaceuticals Inc.

Location:

Beachwood, Rochester Hills, Amherst, Centervilleshow 18 more

Code:

NCT06159673

Conditions

Alzheimer's Disease Psychosis

Eligibility Criteria

Sex: All

Age: 55 - 70+

Healthy Volunteers: Not accepted

Interventions

ACP-204

Placebo

A Study of Brepocitinib in Adults With Active, Non-Infectious, Non-Anterior Uveitis

Recruiting
PHASE3

Sponsor:

Priovant Therapeutics, Inc.

Location:

Cleveland, Detroit, Erie, Ann Arborshow 33 more

Code:

NCT06431373

Conditions

Uveitis, Posterior

Uveitis, Intermediate

Uveitis

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Brepocitinib PO QD

Placebo PO QD

Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Recruiting

Sponsor:

Dennis M. McNamara, MD, MS

Location:

Cleveland, Detroit, Pittsburgh, Ann Arborshow 43 more

Code:

NCT05180773

Conditions

Peripartum Cardiomyopathy, Postpartum

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Bromocriptine

Placebo

Guideline Directed Medical Therapy for Heart Failure (GDMT)

Rivaroxaban

Second Placebo

A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)

Recruiting
PHASE2

Sponsor:

Amgen

Location:

Canton, Southfield, Manassas, Chicagoshow 20 more

Code:

NCT06660173

Conditions

Type 2 Diabetes Mellitus (T2DM)

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Maridebart Cafraglutide

Placebo

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

Recruiting
PHASE3

Sponsor:

Pfizer

Location:

Willoughby Hills, Willoughby, Mentor, Chardonshow 93 more

Code:

NCT04173273

Conditions

Crohn's Disease

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Etrasimod

Placebo

A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)

Recruiting
PHASE1
PHASE2

Sponsor:

Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Location:

Cleveland, Detroit, Buffalo, Milwaukeeshow 7 more

Code:

NCT04471727

Conditions

Small-Cell Lung Cancer

Neuroendocrine Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

MK-6070

Atezolizumab

Ifinatamab Deruxtecan (I-DXd)

A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy

Recruiting

Sponsor:

Jazz Pharmaceuticals

Location:

Cleveland, Dublin, Lansing, Cincinnatishow 29 more

Code:

NCT05869773

Conditions

Narcolepsy

Eligibility Criteria

Sex: All

Age: 18 - 70

Healthy Volunteers: Not accepted

Interventions

JZP258