Discover hundreds of clinical trials in Ohio.
Search clinical trials in Ohio by city, condition or phase.
Sponsor:
AbbVie
Location:
Code:
NCT04777357
Conditions
Depression
Bipolar I Disorder
Eligibility Criteria
Sex: All
Age: 10 - 17
Healthy Volunteers: Not accepted
Interventions
Cariprazine
Placebo
Sponsor:
Indiana University
Location:
Code:
NCT04497857
Conditions
Schizophrenia
Schizoaffective Disorder
Schizophreniform Disorders
Major Depression with Psychotic Features
Bipolar Disorder with Psychotic Features
Eligibility Criteria
Sex: All
Age: 16 - 35
Healthy Volunteers: Not accepted
Interventions
Coordinated Specialty Care (CSC)
Sponsor:
Janssen Research & Development, LLC
Location:
Code:
NCT05754957
Conditions
Acute Coronary Syndrome
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Milvexian
Placebo
Sponsor:
Margaret Gatti-Mays
Location:
Code:
NCT06026657
Conditions
Anatomic Stage IV Breast Cancer AJCC v8
HER2-Negative Breast Carcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biospecimen Collection
Computed Tomography
Gemcitabine
Magnetic Resonance Imaging
Naxitamab
Sponsor:
National Cancer Institute (NCI)
Location:
Code:
NCT03871257
Conditions
Low Grade Glioma
Neurofibromatosis Type 1
Visual Pathway Glioma
Eligibility Criteria
Sex: All
Age: 2 - 21
Healthy Volunteers: Not accepted
Interventions
Carboplatin
Magnetic Resonance Imaging
Quality-of-Life Assessment
Questionnaire Administration
Selumetinib Sulfate
Sponsor:
Replimune Inc.
Location:
Code:
NCT03767348
Conditions
Cancer
Melanoma (Skin)
Mismatch Repair Deficiency
Microsatellite Instability
Non-melanoma Skin Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
RP1
nivolumab
Sponsor:
Novartis Pharmaceuticals
Location:
Code:
NCT04174157
Conditions
Spinal Muscular Atrophy (SMA)
Eligibility Criteria
Sex: All
Age: 0 - 70+
Healthy Volunteers: Not accepted
Interventions
Prospective observational registry
Zolgensma
Sponsor:
GlaxoSmithKline
Location:
Code:
NCT06261957
Conditions
Asthma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Salbutamol HFA-134a
Salbutamol HFA-152a
With a robust healthcare network, renowned medical research centers, and innovative treatments, Ohio is a leading destination for a wide range of clinical trials. Institutions such as the Cleveland Clinic, Ohio State University Wexner Medical Center, University Hospitals Cleveland Medical Center, and Nationwide Children’s Hospital are at the forefront of these studies.
Ohio offers distinct advantages in the clinical research landscape. The state's diverse population provides a wide range of participants, enhancing the accuracy and relevance of research outcomes. Ohio is also recognized for its strong research environment, with a focus on medical innovation and pioneering studies in various fields.
By choosing to participate in a clinical trial in Ohio, participants contribute to vital medical research while benefiting from a well-established clinical trial infrastructure supported by top-tier healthcare institutions. This ensures they receive cutting-edge care and support throughout the process.
In Ohio, clinical trials cover a wide range of medical conditions and diseases, reflecting the state's diverse healthcare research landscape.
Ohio is home to leading cancer research centers like the Cleveland Clinic and Ohio State University Comprehensive Cancer Center, which conduct trials on various cancer types, including breast, lung, colorectal, and prostate cancers. These studies often focus on immunotherapies, targeted treatments, and novel drug combinations.
Oncology trials in Ohio are crucial due to the state’s significant cancer burden. Institutions like OSUCCC–James and the Cleveland Clinic are recognized for their commitment to groundbreaking research and patient care.
Institutions like the Cleveland Clinic and Ohio State University Wexner Medical Center are leaders in trials for neurological conditions, including Alzheimer’s disease, Parkinson’s disease, multiple sclerosis (MS), and stroke prevention. Research includes innovative therapies such as deep brain stimulation, new drug treatments, innovative diagnostics tools, and regenerative medicine.
Given the increasing prevalence of neurodegenerative diseases in Ohio’s aging population, these trials are vital for developing more effective treatments and improving the quality of life for patients.
Heart disease is a major focus in Ohio's clinical trials, with cardiovascular studies looking into advanced treatments for conditions like heart failure, coronary artery disease, congenital heart disorders, hypertension, and arrhythmias. These trials often explore the use of new medications, medical devices, and surgical interventions.
Research centers like the Cleveland Clinic, Ohio State University Wexner Medical Center, and University Hospitals are conducting trials on innovative treatments such as gene therapies, advanced medical devices like pacemakers and stents, and novel drug therapies aimed at improving heart function and reducing mortality rates.
Conditions such as rheumatoid arthritis, lupus, inflammatory bowel disease, and Crohn's disease are commonly studied in Ohio. Leading institutions like the Cleveland Clinic, Ohio State University Wexner Medical Center, and University Hospitals are conducting trials on novel biologics, immunosuppressive therapies, targeted therapies, and immunomodulatory drugs designed to better manage disease symptoms and halt progression.
Ohio conducts numerous clinical trials on diabetes, focusing on better glucose control, insulin delivery systems, and new medications aimed at managing both Type 1 and Type 2 diabetes, as well as related endocrine disorders. Major research institutions here also explore conditions like diabetic neuropathy, obesity, thyroid disorders, and metabolic syndrome.
With high rates of diabetes and obesity in the state, these trials are crucial for addressing public health concerns.
In Ohio, clinical trials for respiratory diseases focus on conditions such as asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, and cystic fibrosis as these are prevalent in the state.
Prominent institutions like the Cleveland Clinic, Ohio State University Wexner Medical Center, and University Hospitals are leading trials on innovative treatments, including new inhalation therapies, biologics targeting specific inflammatory pathways, disease management strategies, and advanced drug delivery systems.
Clinical trials in Ohio are regulated through a combination of federal, state, and institutional guidelines to ensure participant safety and ethical conduct. Federal regulations from the FDA oversee the approval of new drugs and medical devices, while Institutional Review Boards (IRBs) review and approve trials to protect participants' rights, privacy, and welfare.
At the state level, the Ohio Department of Health enforces regulations that include strict informed consent requirements, ensuring participants are fully informed about the risks and benefits of a trial. Additionally, Ohio's leading medical institutions, such as the Cleveland Clinic and Ohio State University Wexner Medical Center, follow their own rigorous protocols for patient care and data management, while complying with HIPAA standards to protect patient privacy.
Joining a clinical trial provides early access to cutting-edge treatments and therapies before they become widely available, which is the primary benefit. The benefits for participants in clinical trials also include exceptional care by leading healthcare professionals, with comprehensive monitoring and specialized support throughout the study.
Moreover, participating in clinical trials is vital for advancing medical research, which can lead to transformative breakthroughs in treatments. By taking part, individuals gain access to pioneering medical solutions and play a key role in scientific progress, ultimately improving future healthcare outcomes for others.
Interested in participating in clinical trials but worried about how long they might take? Check out our comprehensive guide for all the information you need to make an informed decision.
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