Frontotemporal Dementia Clinical Trials

Find clinical trials for frontotemporal dementia. Search for frontotemporal dementia clinical trials in different cities and states across the United States.

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Results: 32

Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 TrialLemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

Recruiting

Sponsor:

Nova Scotia Health Authority

Location:

Halifax

Code:

NCT06093126

Conditions

Insomnia

Dementia

Frontotemporal Dementia

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Lemborexant 5 MG

A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)

Recruiting

Sponsor:

Sanofi

Location:

Chicago IL, Cincinnati OH, Columbus OH, Philadelphia PA

Code:

NCT06192576

Conditions

Niemann-Pick Diseases

Acid Sphingomyelinase Deficiency

Eligibility Criteria

Sex: All

Age: 0 - 2

Healthy Volunteers: Not accepted

Interventions

Olipudase alfa

A Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 GenesA Study of PBFT02 in Participants With FTD and Mutations in the Granulin Precursor (GRN) or C9ORF72 Genes

Recruiting

PHASE1

PHASE2

Sponsor:

Passage Bio, Inc.

Location:

Philadelphia PA, Houston TX, Toronto, Montreal

Code:

NCT04747431

Conditions

Frontotemporal Dementia

FTD

FTD-GRN

Dementia Frontotemporal

C9orf72

Eligibility Criteria

Sex: All

Age: 35 - 70+

Healthy Volunteers: Not accepted

Interventions

PBFT02

Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type CStudy of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C

Recruiting

PHASE1

PHASE2

Sponsor:

Washington University School of Medicine

Location:

Saint Louis MO

Code:

NCT03471143

Conditions

Niemann-Pick Disease, Type C

Eligibility Criteria

Sex: All

Age: 0 - 6

Healthy Volunteers: Not accepted

Interventions

adrabetadex (2-Hydroxypropyl-Beta-Cyclodextrin)

Diagnosis of Alzheimer's Disease Using Event Related PotentialsDiagnosis of Alzheimer's Disease Using Event Related Potentials

Recruiting

Sponsor:

VA Boston Healthcare System

Location:

Jamaica Plain MA

Code:

NCT02957227

Conditions

Mild Cognitive Impairment

Eligibility Criteria

Sex: All

Age: 50 - 70+

Healthy Volunteers: Not accepted

Interventions

No intervention is part of this study but patients use an EEG device during observational data collection.

Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type CEstablishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C

Recruiting

Sponsor:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Location:

Bethesda MD

Code:

NCT05588167

Conditions

Niemann-Pick Disease, Type C

Eligibility Criteria

Sex: All

Age: 3+

Healthy Volunteers: Not accepted

Subgenual Cingulate Deep Brain STIMulation for Apathetic Behavioral Variant FRONtotemporal DementiaSubgenual Cingulate Deep Brain STIMulation for Apathetic Behavioral Variant FRONtotemporal Dementia

Recruiting

Sponsor:

University Health Network, Toronto

Location:

Toronto

Code:

NCT05699330

Conditions

Frontotemporal Dementia

Deep Brain Stimulation

Eligibility Criteria

Sex: All

Age: 40 - 70+

Healthy Volunteers: Not accepted

Interventions

Bilateral subgenual cingulate deep brain stimulation (SGC DBS)

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

Recruiting

PHASE1

PHASE2

Sponsor:

Prevail Therapeutics

Location:

Maitland FL, Orlando FL, Philadelphia PA

Code:

NCT04408625

Conditions

Frontotemporal Dementia

Eligibility Criteria

Sex: All

Age: 30 - 70+

Healthy Volunteers: Not accepted

Interventions

LY3884963

Methylprednisolone

Optional Sirolimus

Optional Prednisone

UCB Transplant of Inherited Metabolic Diseases with Administration of Intrathecal UCB Derived Oligodendrocyte-Like CellsUCB Transplant of Inherited Metabolic Diseases with Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells

Recruiting

PHASE1

Sponsor:

Joanne Kurtzberg, MD

Location:

Durham NC

Code:

NCT02254863

Conditions

Adrenoleukodystrophy

Batten Disease

Mucopolysaccharidosis II

Leukodystrophy, Globoid Cell

Leukodystrophy, Metachromatic

Eligibility Criteria

Sex: All

Age: 1 - 22

Healthy Volunteers: Not accepted

Interventions

DUOC-01

Modifiable Variables in Parkinsonism (MVP)Modifiable Variables in Parkinsonism (MVP)

Recruiting

Sponsor:

Bastyr University

Location:

Kenmore WA

Code:

NCT02194816

Conditions

Parkinson's Disease

Parkinsonism

MSA - Multiple System Atrophy

Progressive Supranuclear Palsy

Shy-Drager Syndrome

Eligibility Criteria

Sex: All

Age: 19+

Healthy Volunteers: Not accepted