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Paid Clinical Trials Knoxville

Discover 224 paid clinical trials in Knoxville, Tennessee. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

Recruiting
PHASE2

Sponsor:

Gilead Sciences

Location:

Knoxville, Atlanta, Nashville, Louisvilleshow 31 more

Code:

NCT03547973

Conditions

Metastatic Urothelial Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Sacituzumab Govitecan-hziy

Pembrolizumab

Cisplatin

Avelumab

Zimberelimab

Efficacy and Safety Studies of Frexalimab (SAR441344) in Adults With Relapsing Forms of Multiple Sclerosis

Recruiting
PHASE3

Sponsor:

Sanofi

Location:

Knoxville, Greer, Lexington, Charlotteshow 78 more

Code:

NCT06141473

Conditions

Multiple Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 55

Healthy Volunteers: Not accepted

Interventions

Frexalimab

Teriflunomide

Placebo infusion

Placebo tablet

MRI contrast-enhancing agents

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting
PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Knoxville, Alcoa, Corbin, Londonshow 350 more

Code:

NCT03866382

Conditions

Bladder Adenocarcinoma

Bladder Clear Cell Adenocarcinoma

Bladder Mixed Adenocarcinoma

Bladder Neuroendocrine Carcinoma

Bladder Small Cell Neuroendocrine Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Bone Scan

Cabozantinib S-malate

Computed Tomography

Echocardiography

A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy

Recruiting
PHASE3

Sponsor:

AbbVie

Location:

Knoxville, Charlotte, Birmingham, Masonshow 71 more

Code:

NCT05889182

Conditions

Hidradenitis Suppurativa

Eligibility Criteria

Sex: All

Age: 12+

Healthy Volunteers: Not accepted

Interventions

Upadacitinib

Placebo

A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia

Recruiting
PHASE1
PHASE2

Sponsor:

Janssen Research & Development, LLC

Location:

Knoxville, Louisville, Indianapolis, Richmondshow 14 more

Code:

NCT04811560

Conditions

Acute Leukemias

Acute Myeloid Leukemia

Acute Lymphoblastic Leukemia

Eligibility Criteria

Sex: All

Age: 12+

Healthy Volunteers: Not accepted

Interventions

Bleximenib

Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

Recruiting
PHASE2

Sponsor:

SWOG Cancer Research Network

Location:

Knoxville, Alcoa, Corbin, Londonshow 210 more

Code:

NCT05040360

Conditions

Metastatic Malignant Neoplasm in the Liver

Pancreatic Neuroendocrine Tumor

Stage I Pancreatic Neuroendocrine Tumor AJCC v8

Stage II Pancreatic Neuroendocrine Tumor AJCC v8

Stage III Pancreatic Neuroendocrine Tumor AJCC v8

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Capecitabine

Temozolomide

A Study of V940 Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

Recruiting
PHASE3

Sponsor:

Merck Sharp & Dohme LLC

Location:

Knoxville, Marietta, Nashville, Louisvilleshow 33 more

Code:

NCT06077760

Conditions

Non-small Cell Lung Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

V940

Pembrolizumab

Placebo

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation

Recruiting
PHASE3

Sponsor:

Novo Nordisk A/S

Location:

Knoxville, Johns Creek, Lexington, Atlantashow 157 more

Code:

NCT05636176

Conditions

Heart Failure

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Ziltivekimab

Placebo

A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain

Recruiting
PHASE2

Sponsor:

Eli Lilly and Company

Location:

Knoxville, Lexington, Hickory, Morehead Cityshow 29 more

Code:

NCT06074562

Conditions

Diabetic Peripheral Neuropathy

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

LY3556050

Placebo

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs (IGNYTE-3)

Recruiting
PHASE3

Sponsor:

Replimune Inc.

Location:

Knoxville, Louisville, Chapel Hill, Durhamshow 12 more

Code:

NCT06264180

Conditions

Advanced Melanoma

Eligibility Criteria

Sex: All

Age: 12+

Healthy Volunteers: Not accepted

Interventions

Vusolimogene Oderparepvec

Nivolumab

Nivolumab + Relatlimab

Pembrolizumab

Single-agent chemotherapy