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Paid Clinical Trials Charleston

Discover 676 paid clinical trials in Charleston, South Carolina. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

Recruiting
PHASE2

Sponsor:

Gilead Sciences

Location:

Charleston, Atlanta, Roanoke, Knoxvilleshow 31 more

Code:

NCT03547973

Conditions

Metastatic Urothelial Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Sacituzumab Govitecan-hziy

Pembrolizumab

Cisplatin

Avelumab

Zimberelimab

Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)

Recruiting
PHASE1
PHASE2

Sponsor:

Merck Sharp & Dohme LLC

Location:

Charleston, Cary, Baltimore, Pittsburghshow 7 more

Code:

NCT02861573

Conditions

Metastatic Castration-Resistant Prostate Cancer

Eligibility Criteria

Sex: Male

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Pembrolizumab 200 mg

Olaparib 400 mg

Docetaxel 75 mg/m^2

Prednisone 5 mg

Enzalutamide 160 mg

Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Recruiting

Sponsor:

Dennis M. McNamara, MD, MS

Location:

Charleston, Jacksonville, Gainesville, Atlantashow 43 more

Code:

NCT05180773

Conditions

Peripartum Cardiomyopathy, Postpartum

Eligibility Criteria

Sex: Female

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Bromocriptine

Placebo

Guideline Directed Medical Therapy for Heart Failure (GDMT)

Rivaroxaban

Second Placebo

A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.

Recruiting
PHASE3

Sponsor:

AstraZeneca

Location:

Charleston, Columbia, Wilmington, Jacksonvilleshow 121 more

Code:

NCT06268873

Conditions

Chronic Kidney Disease and Hypertension

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Baxdrostat/dapagliflozin

Dapagliflozin in combination with placebo

A Study to Evaluate Safety, Efficacy of FF-10832 in Combo With Pembrolizumab in Urothelial & Non-small Cell Lung Cancer

Recruiting
PHASE2

Sponsor:

Fujifilm Pharmaceuticals U.S.A., Inc.

Location:

Charleston, Lexington, Fairfax, Washingtonshow 16 more

Code:

NCT05318573

Conditions

Advanced Urothelial Carcinoma

Advanced Non Small Cell Lung Cancer

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Pembrolizumab

FF-10832

Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of EP262 in Subjects With Chronic Spontaneous Urticaria

Recruiting
PHASE2

Sponsor:

Escient Pharmaceuticals, Inc

Location:

North Charleston, Asheville, Tampa, Birminghamshow 32 more

Code:

NCT06077773

Conditions

Chronic Spontaneous Urticaria

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Oral EP262

Placebo

Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt Versus Stent (The COMPASS Trial)

Recruiting

Sponsor:

Carelon Research

Location:

Charleston, Charlotte, Atlanta, Birminghamshow 20 more

Code:

NCT05268094

Conditions

Congenital Heart Disease in Children

Eligibility Criteria

Sex: All

Age: 1 - 30

Healthy Volunteers: Not accepted

Interventions

Ductal Arterial Stent

Systemic-to-Pulmonary Artery Shunt

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

Recruiting

Sponsor:

Children's Hospital Medical Center, Cincinnati

Location:

Charleston, Charlotte, Durham, Gainesvilleshow 53 more

Code:

NCT02852031

Conditions

Hypoplastic Left Heart Syndrome (HLHS)

Eligibility Criteria

Sex: All

Age: 0 - 15

Healthy Volunteers: Not accepted

Interventions

Collaborative Learning Network

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Recruiting
PHASE2

Sponsor:

National Cancer Institute (NCI)

Location:

Charleston, Chapel Hill, Hendersonville, Johns Creekshow 350 more

Code:

NCT03866382

Conditions

Bladder Adenocarcinoma

Bladder Clear Cell Adenocarcinoma

Bladder Mixed Adenocarcinoma

Bladder Neuroendocrine Carcinoma

Bladder Small Cell Neuroendocrine Carcinoma

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Biospecimen Collection

Bone Scan

Cabozantinib S-malate

Computed Tomography

Echocardiography

Phase III Efficacy and Safety Study of Miconazole Oil for Otomycosis

Recruiting
PHASE3

Sponsor:

Hill Dermaceuticals, Inc.

Location:

North Charleston, Orangeburg, Spartanburg, Louisvilleshow 3 more

Code:

NCT05660382

Conditions

Otomycosis

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

Miconazole (2%) oil and mineral oil

Placebo