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Paid Clinical Trials St. Louis

Discover 1,402 paid clinical trials in St. Louis, Missouri. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.

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FeaturedActive & Responsive

A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251

for
Geographic Atrophy
Location: St Louis MO, Nashville TN, Blue Ash OH, Lynchburg VA,
Sponsor: Genentech, Inc.

Sex: All

Age: 50+

Code: NCT05626114

Phase 2, Recruiting
FeaturedActive & Responsive

Type 2 Diabetes Studies on Blood Sugar and Weight Management for Adults Not on Insulin

for
Diabetes Mellitus, Type 2, Obesity
Location: Saint Louis MO, Valparaiso IN, Cincinnati OH, Omaha NE,

Sex: All

Age: 18 - 70+

Recruiting
FeaturedActive & Responsive

Weight Loss Studies for Adults With a BMI of 27+, Including People Managing Type 2 Diabetes or Sleep Apnea

for
Obesity, Overweight, Diabetes Mellitus, Type 2,
Location: Saint Louis MO, Valparaiso IN, Cincinnati OH, Omaha NE,

Sex: All

Age: 18+

Recruiting
Featured

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

for
Crohn's Disease
Location: St Louis MO, Springfield IL, Columbia MO, Peoria IL,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT06548542

Phase 2, Recruiting
Featured

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

for
Metastatic Pancreatic Ductal Adenocarcinoma, PDAC
Location: St Louis MO, Chicago IL, Zion IL, Grand Rapids MI,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07490301

Phase 2, Phase 3, Recruiting

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Featured

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

for
Hepatocellular Carcinoma, Pancreatic Ductal Adenocarcinoma,
Location: St Louis MO, Denver CO, Nashville TN, Chicago IL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06084481

Phase 1, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for
Hepatocellular Cancer, Squamous-Cell Non-Small Cell Lung Cancer
Location: St Louis MO, Nashville TN, Chicago IL, Philadelphia PA,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT06858813

Phase 1, Recruiting
Featured

A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)

for
Non-small Cell Lung Cancer
Location: St Louis MO, Columbia MO, Memphis TN, DeKalb IL,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT04302025

Phase 2, Recruiting
Featured

A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for
Breast Cancer
Location: St Louis MO, Nashville TN, Zion IL, Huntsville AL,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07100106

Phase 1, Phase 2, Recruiting
Featured

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

for
Parkinson's Disease
Location: St Louis MO, Kansas City KS, Memphis TN, Nashville TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07174310

Phase 3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease

for
Von Willebrand Disease, Type 3
Location: St Louis MO, Lexington KY, Minneapolis MN, Toronto,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 0+

Code: NCT06998524

Phase 3, Recruiting
Featured

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

for
Atherosclerosis
Location: St Louis MO, Hammond IN, Nashville TN, Omaha NE,
Sponsor: Genentech, Inc.

Sex: All

Age: 18+

Code: NCT07448038

Phase 2, Recruiting
Featured

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

for
Alzheimers Disease
Location: St Louis MO, Nashville TN, Chicago IL, Knoxville TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 50 - 70+

Code: NCT07177352

Phase 3, Recruiting
Featured

A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)

for
Acute Myeloid Leukemia
Location: St Louis MO, Atlanta GA, Houston TX, Tampa FL,
Sponsor: AbbVie

Sex: All

Age: 18+

Code: NCT07581002

Phase 2, Phase 3, Recruiting
Featured

A Study to Evaluate the Pharmacokinetics, Safety and Efficacy of Afimkibart (RO7790121) in Children With Moderately to Severely Active Ulcerative Colitis

for
Moderately to Severely Active Ulcerative Colitis
Location: St Louis MO, Atlanta GA, Pittsburgh PA, Toronto,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 2 - 17

Code: NCT07158242

Phase 3, Recruiting
Featured

Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

for
Neovascular Age-related Macular Degeneration
Location: St Louis MO, Springfield IL, Carmel IN, Lenexa KS,
Sponsor: AbbVie

Sex: All

Age: 50+

Code: NCT07007065

Phase 3, Recruiting
Featured

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for
Moderately to Severely Active Crohns Disease
Location: St Louis MO, Columbia MO, Kansas City KS, Cordova TN,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 16 - 70+

Code: NCT06819891

Phase 3, Recruiting
Featured

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

for
Crohn's Disease, Ulcerative Colitis
Location: St Louis MO, New Albany IN, Memphis TN, Louisville KY,
Sponsor: AbbVie

Sex: All

Age: 18 - 70+

Code: NCT07697456

Phase 2, Recruiting
Featured

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

for
Non-Small Cell Lung Cancer, KRAS G12C Lung Cancer
Location: St Louis MO, Iowa City IA, Memphis TN, Chicago Ridge IL,
Sponsor: Hoffmann-La Roche

Sex: All

Age: 18+

Code: NCT06793215

Phase 3, Recruiting
Featured

A Study to Assess Anti-Tumor Activity of Intravenously (IV) Infused Carboplatin With Mirvetuximab Soravtansine in Participants With Newly Diagnosed Folate Receptor Alpha (FRα)Expressing Advanced-Stage Serous Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer.

for
Epithelial Ovarian Cancer, Fallopian Tube Cancer,
Location: St Louis MO, Peoria IL, Urbana IL, Springfield MO,
Sponsor: AbbVie

Sex: Female

Age: 18+

Code: NCT06890338

Phase 2, Recruiting