Clinical Trials In St. Louis
Discover hundreds of clinical trials in St. Louis.
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A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma
Sponsor:
National Cancer Institute (NCI)
Location:
Code:
NCT03871257
Conditions
Low Grade Glioma
Neurofibromatosis Type 1
Visual Pathway Glioma
Eligibility Criteria
Sex: All
Age: 2 - 21
Healthy Volunteers: Not accepted
Interventions
Carboplatin
Magnetic Resonance Imaging
Quality-of-Life Assessment
Questionnaire Administration
Selumetinib Sulfate
Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
Sponsor:
Novartis Pharmaceuticals
Location:
Code:
NCT04174157
Conditions
Spinal Muscular Atrophy (SMA)
Eligibility Criteria
Sex: All
Age: 0 - 70+
Healthy Volunteers: Not accepted
Interventions
Prospective observational registry
Zolgensma
Deimplementing CXR After CVC (DRAUP) in the ICU
Sponsor:
Washington University School of Medicine
Location:
Code:
NCT06146348
Conditions
Implementation Science
Behavior and Behavior Mechanisms
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
adapted DRAUP strategy bundle
Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy
Sponsor:
Academic and Community Cancer Research United
Location:
Code:
NCT06238648
Conditions
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Primary Mediastinal Large B-Cell Lymphoma
Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biopsy
Biospecimen Collection
Computed Tomography
Epcoritamab
Magnetic Resonance Imaging
AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension
Sponsor:
AbbVie
Location:
Code:
NCT04499248
Conditions
Open-angle Glaucoma
Ocular Hypertension
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
AGN-193408 SR
Lumigan
Sham Administration
Lumigan Vehicle
Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT
Sponsor:
Medical University of South Carolina
Location:
Code:
NCT05442957
Conditions
Head and Neck Cancer
Body Image Disturbance
Body Image
Survivorship
Psychosocial Impairment
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
BRIGHT
Attention Control
Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors
Sponsor:
Emory University
Location:
Code:
NCT04469530
Conditions
Solid Tumor
Eligibility Criteria
Sex: All
Age: 1 - 30
Healthy Volunteers: Not accepted
Interventions
Sirolimus
Cyclophosphamide
Etoposide
Celecoxib
A Study to Describe the Characteristics, Health Care Interventions and Outcomes of Patients With Major Bleedings in the Presence of Factor Xa Inhibitor Treatment
Sponsor:
AstraZeneca
Location:
Code:
NCT06147830
Conditions
Major Bleeding
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
None (Observational study)
A Study of Multiple Therapies in Biomarker-Selected Patients With Resectable Stages IB-III Non-Small Cell Lung Cancer
Sponsor:
Genentech, Inc.
Location:
Code:
NCT04302025
Conditions
Non-small Cell Lung Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Alectinib
Entrectinib
Vemurafenib (Enrollment closed)
Cobimetinib (Enrollment closed)
Pralsetinib (Enrollment closed)
RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy
Sponsor:
Rna Diagnostics Inc.
Location:
Code:
NCT03524430
Conditions
Breast Neoplasm Female
Eligibility Criteria
Sex: Female
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Core needle biopsy