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Diabetes clinical trials are research studies that evaluate new ways to prevent, diagnose, treat, and manage diabetes. These trials are essential for testing the safety and effectiveness of new medications, therapies, and devices for both Type 1 and Type 2 diabetes. Through these studies, researchers gain insights that can lead to advancements in diabetes care and treatment.
Clinical trials play a vital role in diabetes research by providing scientifically validated data on the effectiveness and safety of new treatments. These studies are the foundation for developing innovative therapies that can improve blood sugar control, reduce complications, and enhance the quality of life for people living with diabetes.
Clinical trials for Type 1 and Type 2 diabetes serve distinct purposes due to the differences in the underlying causes and treatment approaches for each type of diabetes. This difference highlights the need for specific research strategies for each diabetes type, based on their unique underlying causes and treatment needs.
Type 1 diabetes clinical trials often focus on the autoimmune nature of the disease, seeking to understand how the body's immune system attacks insulin-producing cells and how this process can be halted or reversed. These trials may test immunotherapies, beta cell regeneration techniques, and novel insulin delivery systems that mimic the pancreas's natural function, aiming to preserve or restore insulin production.
Type 2 diabetes trials, on the other hand, typically concentrate on improving insulin sensitivity and managing blood glucose levels through new medications, dietary interventions, exercise programs, and weight management strategies. Given that Type 2 diabetes is often related to lifestyle factors and metabolic syndrome, these trials also explore the effectiveness of interventions in preventing or delaying the onset of diabetes in high-risk individuals.
Some trials are designed to address issues common to both types of diabetes or explore treatments that could benefit both Type 1 and Type 2 diabetes patients. Comparative studies assess the effectiveness across diabetes types, while dual focus trials explore interventions applicable to both conditions, such as cardiovascular health improvements.
Eligibility for diabetes clinical trials varies depending on the study's focus. Trials may be open to individuals with Type 1 or Type 2 diabetes, those at risk of developing diabetes, or even healthy volunteers in prevention studies. Criteria can include age, diabetes type and stage, and overall health status.
Clinical trials for diabetes follow a structured process, beginning with a trial design to define the study's goals, methods, and participant criteria. Trials typically proceed through several phases, starting with small safety studies and expanding to larger efficacy trials. Participants are closely monitored, and data is collected to assess the treatment's impact on diabetes management and outcomes.
Participants can expect thorough medical evaluations, detailed information about the study, and close monitoring of their health throughout the trial. Informed consent is obtained before participation, ensuring that individuals understand the trial's purpose, procedures, and potential risks and benefits.
Participating in diabetes clinical trials comes with both benefits and risks. Participants may gain early access to new treatments and management strategies that are not yet widely available, offering potential improvements in their diabetes care.
However, there are also risks involved, including the possibility of experiencing side effects or adverse reactions to the treatments being tested. Trials may also demand a significant time commitment, involving regular monitoring and follow-up appointments.
Dive into our comprehensive guide to learn about the process, benefits, and potential impact of your involvement. Get the facts you need to make an informed decision today!
Enrolling in a diabetes clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started:
Sponsor:
CARGO Therapeutics
Location:
Code:
NCT05972720
Conditions
Cancer
Relapsed/Refractory Large B-cell Lymphoma (LBCL)
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Fludarabine (Conditional therapy)
Cyclophosphamide Monohydrate (Conditional therapy)
firi-cel (Experimental drug)
Sponsor:
Stemline Therapeutics, Inc.
Location:
Code:
NCT05563220
Conditions
Breast Cancer
Metastatic Breast Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Elacestrant
Alpelisib
Everolimus
Ribociclib
Palbociclib
Sponsor:
Novartis Pharmaceuticals
Location:
Code:
NCT05147220
Conditions
Relapsing Multiple Sclerosis
Eligibility Criteria
Sex: All
Age: 18 - 55
Healthy Volunteers: Not accepted
Interventions
Remibrutinib
Teriflunomide
Sponsor:
University of Rochester
Location:
Code:
NCT05265520
Conditions
Right Bundle-Branch Block
Heart Failure
His-bundle Pacing
Cardiac Resynchronization Therapy
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
His-CRT implantation
BIV-CRT implantation
Sponsor:
Cellectis S.A.
Location:
Code:
NCT05607420
Conditions
B-cell Non-Hodgkin Lymphoma (B-NHL)
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
UCART20x22
CLLS52
Sponsor:
Shirley Ryan AbilityLab
Location:
Code:
NCT05447676
Conditions
Spinal Cord Injury
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Dalfampridine
Placebo drug
STDP stimulation
Exercise training
Sponsor:
Regeneron Pharmaceuticals
Location:
Code:
NCT05831176
Conditions
Eosinophilic Gastritis
Eosinophilic Duodenitis
Eosinophilic Gastrointestinal Disease
Eligibility Criteria
Sex: All
Age: 12+
Healthy Volunteers: Not accepted
Interventions
Dupilumab Dose 1
Dupilumab Dose 2
Matching Placebo
Sponsor:
Northwestern University
Location:
Code:
NCT06081127
Conditions
Breast Cancer
Eligibility Criteria
Sex: Female
Age: 18+
Healthy Volunteers: Not accepted
Interventions
MOve-ABC
Enhanced Usual Care
Sponsor:
AstraZeneca
Location:
Code:
NCT05583227
Conditions
Eosinophilic Esophagitis
Eligibility Criteria
Sex: All
Age: 12 - 70+
Healthy Volunteers: Not accepted
Interventions
Tezepelumab
Placebo
Sponsor:
Otsuka Pharmaceutical Development & Commercialization, Inc.
Location:
Code:
NCT05729373
Conditions
Generalized Anxiety Disorder
Eligibility Criteria
Sex: All
Age: 18 - 65
Healthy Volunteers: Not accepted
Interventions
SEP-363856
Placebo