Discover 3,383 paid clinical trials in Los Angeles, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Sponsor:
Edwards Lifesciences
Location:
Code:
NCT05172973
Conditions
Aortic Valve Insufficiency
Aortic Valve Stenosis
Eligibility Criteria
Sex: All
Age: 0 - 70+
Healthy Volunteers: Not accepted
Interventions
SAPIEN X4 THV
Sponsor:
ALX Oncology Inc.
Location:
Code:
NCT05002127
Conditions
Gastric Cancer
Gastroesophageal Junction Adenocarcinoma
Gastric Adenocarcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Evorpacept (ALX148)
Trastuzumab
Ramucirumab
Paclitaxel
Sponsor:
Gilead Sciences
Location:
Code:
NCT03547973
Conditions
Metastatic Urothelial Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Sacituzumab Govitecan-hziy
Pembrolizumab
Cisplatin
Avelumab
Zimberelimab
Sponsor:
Joseph Tuscano
Location:
Code:
NCT04450173
Conditions
Ann Arbor Stage II Follicular Lymphoma
Ann Arbor Stage III Follicular Lymphoma
Ann Arbor Stage IV Follicular Lymphoma
Grade 1 Follicular Lymphoma
Grade 2 Follicular Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Ibrutinib
Obinutuzumab
Venetoclax
Sponsor:
City of Hope Medical Center
Location:
Code:
NCT05707273
Conditions
B Acute Lymphoblastic Leukemia
Eligibility Criteria
Sex: All
Age: 55+
Healthy Volunteers: Not accepted
Interventions
Autologous Anti-CD19 CAR-expressing T Lymphocytes
Biospecimen Collection
Bone Marrow Aspiration and Biopsy
Cyclophosphamide
Fludarabine
Sponsor:
American Thrombosis and Hemostasis Network
Location:
Code:
NCT04647227
Conditions
Hemophilia A With Inhibitor
Hemophilia B With Inhibitor
Eligibility Criteria
Sex: All
Age: 12 - 70+
Healthy Volunteers: Not accepted
Interventions
coagulation factor VIIa [recombinant]-jncw
Sponsor:
Kowa Research Institute, Inc.
Location:
Code:
NCT05327127
Conditions
NASH
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
K-877-ER
CSG452
Placebo
Sponsor:
Merck Sharp & Dohme LLC
Location:
Code:
NCT02861573
Conditions
Metastatic Castration-Resistant Prostate Cancer
Eligibility Criteria
Sex: Male
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Pembrolizumab 200 mg
Olaparib 400 mg
Docetaxel 75 mg/m^2
Prednisone 5 mg
Enzalutamide 160 mg
Sponsor:
City of Hope Medical Center
Location:
Code:
NCT05672173
Conditions
Recurrent Transformed Chronic Lymphocytic Leukemia
Refractory Transformed Chronic Lymphocytic Leukemia
Richter Syndrome
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biopsy
Biospecimen Collection
Bone Marrow Biopsy
Computed Tomography
Cyclophosphamide
Sponsor:
BioNTech SE
Location:
Code:
NCT04813627
Conditions
Colorectal Cancer Stage II
Colorectal Cancer Stage III
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Regular blood sample collection for ctDNA assessment
With a vast healthcare network and top-tier medical research centers, Los Angeles is a key hub for a wide range of clinical trials. Renowned institutions such as UCLA Health, Cedars-Sinai Medical Center, and the Keck School of Medicine at USC lead pioneering research across various fields, including cancer, cardiovascular health, and neuroscience.
Many Los Angeles medical centers are at the forefront of innovative studies, positioning the city as a critical location for advancing medical research and improving patient care outcomes.
Los Angeles offers distinct advantages for individuals participating in clinical trials. The city’s diverse population provides a wide range of participants, enhancing the accuracy and applicability of research findings across different demographics.
Known for its forward-thinking research environment, Los Angeles is home to leading institutions that drive cutting-edge studies in a variety of medical fields. By choosing to participate in a clinical trial in Los Angeles, individuals contribute to groundbreaking medical research while benefiting from the city's well-established clinical research infrastructure and access to world-class healthcare professionals.
Los Angeles is renowned for its contributions to clinical trials across a variety of medical conditions and diseases, with several institutions leading research in key areas
Los Angeles is at the forefront of research on neurological diseases like Alzheimer's, Parkinson's, and multiple sclerosis (MS). The Mary S. Easton Center for Alzheimer's Disease Research at UCLA runs clinical trials aimed at delaying the onset of neurodegenerative conditions or slowing disease progression. These trials investigate novel pharmaceuticals, including anti-amyloid therapies that target proteins believed to play a role in Alzheimer's, and cutting-edge brain stimulation techniques designed to improve cognitive function.
Trials at USC’s Keck School of Medicine also focus on therapies that could prevent or mitigate the symptoms of Parkinson’s disease and other movement disorders.
The Smidt Heart Institute at Cedars-Sinai is a global leader in heart disease research. It conducts pioneering clinical trials on conditions such as heart failure, arrhythmias, and hypertension. Many of these cardiovascular studies involve minimally invasive procedures and robotic surgeries that improve recovery times and patient outcomes.
Some medical centers in LA also lead research into next-generation cardiac devices, including advanced pacemakers and artificial hearts, while exploring innovative therapies like stem cell treatments to regenerate damaged heart tissue.
Los Angeles, with its high rates of Type 2 diabetes, plays a crucial role in diabetes research. USC’s Diabetes & Obesity Research Institute is leading trials that delve into both the prevention and treatment of diabetes. These studies investigate new medications that regulate blood sugar levels, advanced insulin delivery systems, and emerging technologies like continuous glucose monitors (CGMs), which provide real-time data for better management.
The focus on metabolic health in clinical trials also extends to obesity, where trials are looking at behavioral interventions and bariatric surgery techniques to address this growing public health issue.
Los Angeles is internationally recognized for cancer research, particularly at UCLA’s Jonsson Comprehensive Cancer Center and Cedars-Sinai’s Samuel Oschin Cancer Center. Clinical trials here explore a range of cutting-edge treatments, including CAR-T cell therapy, which reprograms the body’s immune cells to attack cancer, and immunotherapies that boost the body's natural defenses.
These trials often target aggressive forms of cancer, including pancreatic, triple-negative breast, lung, and prostate cancers, offering patients access to the latest experimental treatments and personalized care approaches.
Interested in learning more about how clinical trials for cancer work? Explore our guide to better understand oncology clinical trials and how they contribute to advancing cancer treatmets.
LA is home to some of the most advanced clinical trials in mental health, focusing on psychiatric conditions like depression, anxiety, schizophrenia, and bipolar disorder. Los Angeles researchers are exploring innovative treatments, including psychedelic-assisted therapy with substances like psilocybin and MDMA, which are showing promise for treatment-resistant depression and PTSD.
Other trials look at new antidepressants, digital mental health therapies, and cognitive-behavioral techniques designed to improve long-term mental health outcomes.
Los Angeles has long been at the cutting edge of infectious diseases such as HIV/AIDS research, playing a major role in the development of antiretroviral therapies (ART). Institutions like UCLA and USC conduct clinical trials that are exploring long-acting injectables, antibody therapies, and even potential cures for HIV. Pre-exposure prophylaxis (PrEP) research also continues to evolve in LA, as researchers work to make it more accessible and effective.
LA has also been instrumental in clinical trials for COVID-19 vaccines and treatments, with Cedars-Sinai and other medical centers leading research on antiviral drugs, monoclonal antibodies, and long COVID treatments, making significant contributions to public health on a global scale.
Some clinical trials in Los Angeles focus on advanced orthopedic treatments and regenerative medicine, particularly at Cedars-Sinai and UCLA. These trials explore treatments for joint injuries, spinal conditions, and osteoarthritis using cutting-edge therapies like stem cell injections, gene therapy, and platelet-rich plasma (PRP) treatments, which help repair and regenerate damaged tissues.
LA is also a leader in developing next-generation prosthetics, robotic-assisted surgeries, and minimally invasive techniques that aim to reduce recovery time and improve mobility for patients with chronic joint or spine issues.
In Los Angeles, clinical trials must adhere to strict federal, state, and local regulations to ensure participant safety and ethical research practices. All studies are subject to the U.S. Food and Drug Administration (FDA) guidelines, which require rigorous review and approval processes, including compliance with Good Clinical Practice (GCP) standards. Each clinical trial must also receive approval from an Institutional Review Board (IRB), which is responsible for ensuring that the rights and welfare of participants are protected, that informed consent is obtained, and that the risks are minimized.
At state level, the California Department of Public Health (CDPH) oversees clinical research activities, enforcing regulations related to medical research and the protection of human subjects. In Los Angeles, institutions also have their own internal policies and ethics committees that supplement state and federal guidelines. Additionally, compliance with Health Insurance Portability and Accountability Act (HIPAA) regulations is essential for safeguarding participant health information throughout the clinical trial process.
Enrolling in a clinical trial offers individuals a unique opportunity to experience innovative treatments and therapies that are not yet available to the general public. Participants receive personalized care, with dedicated healthcare professionals closely monitoring their health and progress throughout the duration of the study. This level of attention ensures any potential side effects are managed effectively while also maximizing the benefits of the experimental interventions.
Participation in clinical trials is essential for fostering medical progress, often leading to significant breakthroughs in the treatment and prevention of various diseases. By joining these studies, individuals not only gain early access to potentially transformative therapies but also contribute to the broader scientific community. Clinical trial volunteers are instrumental in enhancing our understanding of medical conditions and refining future healthcare practices.
Enrolling in a clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started: