Discover 3,402 paid clinical trials in Los Angeles. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
Sponsor:
Nuvalent Inc.
Location:
Code:
NCT05384626
Conditions
Locally Advanced Solid Tumor
Metastatic Solid Tumor
Eligibility Criteria
Sex: All
Age: 12+
Healthy Volunteers: Not accepted
Interventions
NVL-655
Sponsor:
City of Hope Medical Center
Location:
Code:
NCT05227326
Conditions
Refractory Malignant Solid Neoplasm
Osteosarcoma
Leiomyosarcomas
Synovial Sarcomas
Ovarian Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
PCNA Inhibitor AOH1996
Sponsor:
Pfizer
Location:
Code:
NCT06398626
Conditions
Colitis, Ulcerative
Eligibility Criteria
Sex: All
Age: 18 - 64
Healthy Volunteers: Not accepted
Interventions
Etrasimod
Sponsor:
Pfizer
Location:
Code:
NCT05287126
Conditions
Ulcerative Colitis
Eligibility Criteria
Sex: All
Age: 12 - 17
Healthy Volunteers: Not accepted
Interventions
Etrasimod
Sponsor:
GB002, Inc.
Location:
Code:
NCT05934526
Conditions
Pulmonary Arterial Hypertension
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Placebo
Seralutinib
Generic Dry Powder Inhaler
Sponsor:
Unity Health Toronto
Location:
Code:
NCT02969226
Conditions
Critically Ill
Eligibility Criteria
Sex: All
Age: 16+
Healthy Volunteers: Not accepted
Interventions
Once daily screening
Twice daily screening
PS SBTs
T-piece SBTs
Sponsor:
Johns Hopkins University
Location:
Code:
NCT06263426
Conditions
Hiv
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
HIV D+/R+
HIV D-/R+
Sponsor:
VistaGen Therapeutics, Inc.
Location:
Code:
NCT06615557
Conditions
Social Anxiety Disorder (SAD)
Eligibility Criteria
Sex: All
Age: 18 - 65
Healthy Volunteers: Not accepted
Interventions
Fasedienol Nasal Spray
Placebo Nasal Spray
Sponsor:
City of Hope Medical Center
Location:
Code:
NCT06130826
Conditions
Breast Carcinoma
Colorectal Carcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biopsy
Biospecimen Collection
Bone Scan
Computed Tomography
Immunotherapy
Sponsor:
TORL Biotherapeutics, LLC
Location:
Code:
NCT05156866
Conditions
Advanced Solid Tumor
Gastric Cancer
Pancreas Cancer
Gastroesophageal Junction Adenocarcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
TORL-2-307-ADC
With a vast healthcare network and top-tier medical research centers, Los Angeles is a key hub for a wide range of clinical trials. Renowned institutions such as UCLA Health, Cedars-Sinai Medical Center, and the Keck School of Medicine at USC lead pioneering research across various fields, including cancer, cardiovascular health, and neuroscience.
Many Los Angeles medical centers are at the forefront of innovative studies, positioning the city as a critical location for advancing medical research and improving patient care outcomes.
Los Angeles offers distinct advantages for individuals participating in clinical trials. The city’s diverse population provides a wide range of participants, enhancing the accuracy and applicability of research findings across different demographics.
Known for its forward-thinking research environment, Los Angeles is home to leading institutions that drive cutting-edge studies in a variety of medical fields. By choosing to participate in a clinical trial in Los Angeles, individuals contribute to groundbreaking medical research while benefiting from the city's well-established clinical research infrastructure and access to world-class healthcare professionals.
Los Angeles is renowned for its contributions to clinical trials across a variety of medical conditions and diseases, with several institutions leading research in key areas
Los Angeles is at the forefront of research on neurological diseases like Alzheimer's, Parkinson's, and multiple sclerosis (MS). The Mary S. Easton Center for Alzheimer's Disease Research at UCLA runs clinical trials aimed at delaying the onset of neurodegenerative conditions or slowing disease progression. These trials investigate novel pharmaceuticals, including anti-amyloid therapies that target proteins believed to play a role in Alzheimer's, and cutting-edge brain stimulation techniques designed to improve cognitive function.
Trials at USC’s Keck School of Medicine also focus on therapies that could prevent or mitigate the symptoms of Parkinson’s disease and other movement disorders.
The Smidt Heart Institute at Cedars-Sinai is a global leader in heart disease research. It conducts pioneering clinical trials on conditions such as heart failure, arrhythmias, and hypertension. Many of these cardiovascular studies involve minimally invasive procedures and robotic surgeries that improve recovery times and patient outcomes.
Some medical centers in LA also lead research into next-generation cardiac devices, including advanced pacemakers and artificial hearts, while exploring innovative therapies like stem cell treatments to regenerate damaged heart tissue.
Los Angeles, with its high rates of Type 2 diabetes, plays a crucial role in diabetes research. USC’s Diabetes & Obesity Research Institute is leading trials that delve into both the prevention and treatment of diabetes. These studies investigate new medications that regulate blood sugar levels, advanced insulin delivery systems, and emerging technologies like continuous glucose monitors (CGMs), which provide real-time data for better management.
The focus on metabolic health in clinical trials also extends to obesity, where trials are looking at behavioral interventions and bariatric surgery techniques to address this growing public health issue.
Los Angeles is internationally recognized for cancer research, particularly at UCLA’s Jonsson Comprehensive Cancer Center and Cedars-Sinai’s Samuel Oschin Cancer Center. Clinical trials here explore a range of cutting-edge treatments, including CAR-T cell therapy, which reprograms the body’s immune cells to attack cancer, and immunotherapies that boost the body's natural defenses.
These trials often target aggressive forms of cancer, including pancreatic, triple-negative breast, lung, and prostate cancers, offering patients access to the latest experimental treatments and personalized care approaches.
Interested in learning more about how clinical trials for cancer work? Explore our guide to better understand oncology clinical trials and how they contribute to advancing cancer treatmets.
LA is home to some of the most advanced clinical trials in mental health, focusing on psychiatric conditions like depression, anxiety, schizophrenia, and bipolar disorder. Los Angeles researchers are exploring innovative treatments, including psychedelic-assisted therapy with substances like psilocybin and MDMA, which are showing promise for treatment-resistant depression and PTSD.
Other trials look at new antidepressants, digital mental health therapies, and cognitive-behavioral techniques designed to improve long-term mental health outcomes.
Los Angeles has long been at the cutting edge of infectious diseases such as HIV/AIDS research, playing a major role in the development of antiretroviral therapies (ART). Institutions like UCLA and USC conduct clinical trials that are exploring long-acting injectables, antibody therapies, and even potential cures for HIV. Pre-exposure prophylaxis (PrEP) research also continues to evolve in LA, as researchers work to make it more accessible and effective.
LA has also been instrumental in clinical trials for COVID-19 vaccines and treatments, with Cedars-Sinai and other medical centers leading research on antiviral drugs, monoclonal antibodies, and long COVID treatments, making significant contributions to public health on a global scale.
Some clinical trials in Los Angeles focus on advanced orthopedic treatments and regenerative medicine, particularly at Cedars-Sinai and UCLA. These trials explore treatments for joint injuries, spinal conditions, and osteoarthritis using cutting-edge therapies like stem cell injections, gene therapy, and platelet-rich plasma (PRP) treatments, which help repair and regenerate damaged tissues.
LA is also a leader in developing next-generation prosthetics, robotic-assisted surgeries, and minimally invasive techniques that aim to reduce recovery time and improve mobility for patients with chronic joint or spine issues.
In Los Angeles, clinical trials must adhere to strict federal, state, and local regulations to ensure participant safety and ethical research practices. All studies are subject to the U.S. Food and Drug Administration (FDA) guidelines, which require rigorous review and approval processes, including compliance with Good Clinical Practice (GCP) standards. Each clinical trial must also receive approval from an Institutional Review Board (IRB), which is responsible for ensuring that the rights and welfare of participants are protected, that informed consent is obtained, and that the risks are minimized.
At state level, the California Department of Public Health (CDPH) oversees clinical research activities, enforcing regulations related to medical research and the protection of human subjects. In Los Angeles, institutions also have their own internal policies and ethics committees that supplement state and federal guidelines. Additionally, compliance with Health Insurance Portability and Accountability Act (HIPAA) regulations is essential for safeguarding participant health information throughout the clinical trial process.
Enrolling in a clinical trial offers individuals a unique opportunity to experience innovative treatments and therapies that are not yet available to the general public. Participants receive personalized care, with dedicated healthcare professionals closely monitoring their health and progress throughout the duration of the study. This level of attention ensures any potential side effects are managed effectively while also maximizing the benefits of the experimental interventions.
Participation in clinical trials is essential for fostering medical progress, often leading to significant breakthroughs in the treatment and prevention of various diseases. By joining these studies, individuals not only gain early access to potentially transformative therapies but also contribute to the broader scientific community. Clinical trial volunteers are instrumental in enhancing our understanding of medical conditions and refining future healthcare practices.
Enrolling in a clinical trial through our platform is a straightforward and user-friendly process. Here's how to get started: