Paid Clinical Trials Irvine
Discover 3,403 paid clinical trials in Irvine, California. Search by condition or phase to find a research study near you that matches your needs across various therapeutic areas.
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
Sponsor:
Edwards Lifesciences
Location:
Code:
NCT05172973
Conditions
Aortic Valve Insufficiency
Aortic Valve Stenosis
Eligibility Criteria
Sex: All
Age: 0 - 70+
Healthy Volunteers: Not accepted
Interventions
SAPIEN X4 THV
A Study of Evorpacept (ALX148) in Patients with Advanced HER2+ Gastric Cancer (ASPEN-06)
Sponsor:
ALX Oncology Inc.
Location:
Code:
NCT05002127
Conditions
Gastric Cancer
Gastroesophageal Junction Adenocarcinoma
Gastric Adenocarcinoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Evorpacept (ALX148)
Trastuzumab
Ramucirumab
Paclitaxel
Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread
Sponsor:
Gilead Sciences
Location:
Code:
NCT03547973
Conditions
Metastatic Urothelial Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Sacituzumab Govitecan-hziy
Pembrolizumab
Cisplatin
Avelumab
Zimberelimab
Obinutuzumab, Ibrutinib, and Venetoclax for the Treatment of Previously Untreated Stage II-IV Follicular Lymphoma
Sponsor:
Joseph Tuscano
Location:
Code:
NCT04450173
Conditions
Ann Arbor Stage II Follicular Lymphoma
Ann Arbor Stage III Follicular Lymphoma
Ann Arbor Stage IV Follicular Lymphoma
Grade 1 Follicular Lymphoma
Grade 2 Follicular Lymphoma
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Ibrutinib
Obinutuzumab
Venetoclax
CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission
Sponsor:
City of Hope Medical Center
Location:
Code:
NCT05707273
Conditions
B Acute Lymphoblastic Leukemia
Eligibility Criteria
Sex: All
Age: 55+
Healthy Volunteers: Not accepted
Interventions
Autologous Anti-CD19 CAR-expressing T Lymphocytes
Biospecimen Collection
Bone Marrow Aspiration and Biopsy
Cyclophosphamide
Fludarabine
SEVENFACT® for Bleeding Events in Hemophilia With Inhibitors
Sponsor:
American Thrombosis and Hemostasis Network
Location:
Code:
NCT04647227
Conditions
Hemophilia A With Inhibitor
Hemophilia B With Inhibitor
Eligibility Criteria
Sex: All
Age: 12 - 70+
Healthy Volunteers: Not accepted
Interventions
coagulation factor VIIa [recombinant]-jncw
Study to Evaluate the Efficacy and Safety of K-877-ER and CSG452 in Participants With NASH With Liver Fibrosis
Sponsor:
Kowa Research Institute, Inc.
Location:
Code:
NCT05327127
Conditions
NASH
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
K-877-ER
CSG452
Placebo
Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)
Sponsor:
Merck Sharp & Dohme LLC
Location:
Code:
NCT02861573
Conditions
Metastatic Castration-Resistant Prostate Cancer
Eligibility Criteria
Sex: Male
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Pembrolizumab 200 mg
Olaparib 400 mg
Docetaxel 75 mg/m^2
Prednisone 5 mg
Enzalutamide 160 mg
Lisocabtagene Maraleucel, Nivolumab and Ibrutinib for the Treatment of Richter's Transformation
Sponsor:
City of Hope Medical Center
Location:
Code:
NCT05672173
Conditions
Recurrent Transformed Chronic Lymphocytic Leukemia
Refractory Transformed Chronic Lymphocytic Leukemia
Richter Syndrome
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Biopsy
Biospecimen Collection
Bone Marrow Biopsy
Computed Tomography
Cyclophosphamide
Epidemiological Study to Monitor Study Participants With Resected Stage II (High Risk) or Stage III Colorectal Cancer for Circulating Tumor DNA Before, During and After Their Treatment With Adjuvant Chemotherapy
Sponsor:
BioNTech SE
Location:
Code:
NCT04813627
Conditions
Colorectal Cancer Stage II
Colorectal Cancer Stage III
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Regular blood sample collection for ctDNA assessment