Macular Degeneration Clinical Trials

Find clinical trials for macular degeneration. Search for macular degeneration clinical trials in different cities and states across the United States.

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Results: 125

Pozelimab & CemdisiranA Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy

Recruiting

PHASE3

Sponsor:

Regeneron Pharmaceuticals

Location:

Phoenix AZ, Beverly Hills CA, Fullerton CA, Huntington Beach CAshow 57 more

Code:

NCT06541704

Conditions

Age-related Macular Degeneration (AMD)

Geographic Atrophy (GA)

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Interventions

Pozelimab

Cemdisiran

Placebo

Observational StudyLearning Study: Improving Vision in Adults With Macular Degeneration

Recruiting

Sponsor:

University of Waterloo

Location:

Waterloo

Code:

NCT04762368

Conditions

Macular Degeneration

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Active anodal tDCS

Sham anodal tDCS

InfliximabIntravitreal Infliximab for Diabetic Macular Edema (DME) and Choroidal Neovascularization (CNV)

Recruiting

PHASE1

Sponsor:

Retina Research Foundation

Location:

SLingerlands NY

Code:

NCT00695682

Conditions

Diabetic Retinopathy

Macular Degeneration

Eligibility Criteria

Sex: All

Age: 0 - 70+

Healthy Volunteers: Not accepted

Interventions

intravitreal injection of infliximab

RGX-314Phase 2 Trial of RGX-314 in Adults With Center Involved - Diabetic Macular Edema (CI - DME)

Recruiting

PHASE2

Sponsor:

Sierra Eye Associates

Location:

Reno NV

Code:

NCT06942520

Conditions

Diabetic Macular Edema

Eligibility Criteria

Sex: All

Age: 25 - 70+

Healthy Volunteers: Not accepted

Interventions

RGX-314 Dose 1

RGX-314 Dose 2

Aflibercept (2.0 mg)

Observational StudyDark Adaptation in Participants With Age-Related Macular Degeneration

Recruiting

Sponsor:

National Eye Institute (NEI)

Location:

Bethesda MD

Code:

NCT03225131

Conditions

Age-Related Macular Degeneration

Eligibility Criteria

Sex: All

Age: 50 - 70+

Healthy Volunteers: Not accepted

NG101NG101 AAV Gene Therapy in Subjects with Wet Age-Related Macular Degeneration

Recruiting

PHASE1

PHASE2

Sponsor:

Neuracle Genetics, Inc

Location:

Cincinnati OH, Vancouver, Toronto

Code:

NCT05984927

Conditions

Age-Related Macular Degeneration

Eligibility Criteria

Sex: All

Age: 50 - 70+

Healthy Volunteers: Not accepted

Interventions

NG101 AAV gene therapy

N-acetylcysteineOral N-acetylcysteine for Retinitis Pigmentosa

Recruiting

PHASE3

Sponsor:

Johns Hopkins University

Location:

Davis CA, Los Angeles CA, San Francisco CA, Stanford CAshow 21 more

Code:

NCT05537220

Conditions

Retinitis Pigmentosa

Eligibility Criteria

Sex: All

Age: 18 - 65

Healthy Volunteers: Not accepted

Interventions

N-acetylcysteine

Placebo

OCU-10-C-110Safety and Tolerability of OCU-10-C-110 for Injection in Subjects With Neovascular Age-related Macular Degeneration

Recruiting

PHASE1

Sponsor:

Ocugenix Corporation

Location:

Carmel IN, Abilene TX, Willow Park TX

Code:

NCT05904691

Conditions

Neovascular Age-related Macular Degeneration (nAMD)

Eligibility Criteria

Sex: All

Age: 50+

Healthy Volunteers: Not accepted

Interventions

OCU-10-C-110 for Injection

ALK-001Phase 2 Tolerability and Effects of ALK-001 on Stargardt Disease

Recruiting

PHASE2

Sponsor:

Alkeus Pharmaceuticals, Inc.

Location:

Los Angeles CA, Gainesville FL, Miami FL, Baltimore MDshow 4 more

Code:

NCT02402660

Conditions

Stargardt Disease

Stargardt Macular Degeneration

Stargardt Macular Dystrophy

Autosomal Recessive Stargardt Disease 1 (ABCA4-related)

Eligibility Criteria

Sex: All

Age: 8 - 70

Healthy Volunteers: Not accepted

Interventions

ALK-001

Placebo

EC-104EC-104 Intravitreal Implant for the Treatment of Diabetic Macular Edema

Recruiting

PHASE1

PHASE2

Sponsor:

Eclipse Life Sciences, Inc.

Location:

Tampa FL

Code:

NCT06536491

Conditions

Diabetic Macular Edema

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

EC-104 high dose

EC-104 low dose

Dexamethasone intravitreal implant