Find clinical trials for Kidney Disease. Search for Kidney Disease clinical trials in different cities and states across the United States.
Sponsor:
CAMC Health System
Location:
Code:
NCT04279457
Conditions
AKI (Acute Kidney Injury) Due to Trauma
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
DyeVert Plus System
Standardized hydration protocol
Sponsor:
University of Texas Southwestern Medical Center
Location:
Code:
NCT06003348
Conditions
Calcium Phosphate Kidney Stones
Eligibility Criteria
Sex: All
Age: 21 - 70+
Healthy Volunteers: Not accepted
Interventions
OHCit- standard dose
Potassium Citrate
Placebo
OHCit- low dose
Sponsor:
Azienda Ospedaliero-Universitaria Careggi
Location:
Code:
NCT05363657
Conditions
Kidney Cancer
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Partial Nephrectomy (PN)
Radical Nephrectomy (RN)
Ablation therapy (AT)
Active Surveillance (AS)
Sponsor:
Regeneron Pharmaceuticals
Location:
Code:
NCT03972657
Conditions
Metastatic Castration-resistant Prostate Cancer (mCRPC)
Clear Cell Renal Cell Carcinoma (ccRCC)
Eligibility Criteria
Sex: Male
Age: 18+
Healthy Volunteers: Not accepted
Interventions
REGN5678
Cemiplimab
Sponsor:
The University of Queensland
Location:
Code:
NCT04932148
Conditions
Kidney Failure
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Incremental HD
Conventional HD
Sponsor:
New York Medical College
Location:
Code:
NCT04308330
Conditions
Ewing Sarcoma
Rhabdomyosarcoma
Wilms Tumor
Neuroblastoma
Hepatoblastoma
Eligibility Criteria
Sex: All
Age: 1 - 30
Healthy Volunteers: Not accepted
Interventions
Vorinostat
Sponsor:
Travera Inc
Location:
Code:
NCT05461430
Conditions
Pleural Effusion, Malignant
Ascites, Malignant
Carcinoma
Carcinoma, Hepatocellular
Carcinoma, Renal Cell
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Sponsor:
Washington D.C. Veterans Affairs Medical Center
Location:
Code:
NCT06110130
Conditions
Chronic Kidney Diseases
Eligibility Criteria
Sex: All
Age: 19 - 70+
Healthy Volunteers: Not accepted
Interventions
Empagliflozin 10 MG
Placebo
Sponsor:
Children's Hospital Medical Center, Cincinnati
Location:
Code:
NCT02143830
Conditions
Fanconi Anemia
Severe Marrow Failure
Myelodysplastic Syndrome (MDS)
Acute Myelogenous Leukemia (AML)
Eligibility Criteria
Sex: All
Age: 3+
Healthy Volunteers: Not accepted
Interventions
Busulfan
Cyclophosphamide
Fludarabine
rabbit ATG
G-CSF
Sponsor:
University of Pennsylvania
Location:
Code:
NCT05738330
Conditions
End Stage Kidney Disease
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Symptom Monitoring on Renal Replacement Therapy - Hemodialysis (SMaRRT-HD)
Usual Care
Clinical trials for kidney disease are research studies designed to test new treatments, interventions, or diagnostic methods aimed at improving the management and outcomes of kidney conditions including kidney disease. These trials may involve experimental medications, innovative therapies, surgical techniques, or lifestyle interventions.
Kidney disease clinical trials are crucial because they help advance our understanding of kidney disorders so that more effective treatments can be developed. These trials test new drugs, therapies, and diagnostic methods, aiming to improve patient outcomes, slow disease progression, and enhance quality of life.
Clinical trials for kidney disease also provide valuable data on the safety and efficacy of new interventions, which can lead to better management strategies and potential cures. Without clinical trials, the development of innovative solutions and improvements in care for kidney disease would be limited, potentially leaving patients with fewer options and suboptimal outcomes.
Clinical trials for kidney disease can take on many different forms. Researchers will choose the method that best suits the objectives and expected outcomes of the research.
Prevention trials are designed to identify and test strategies that can prevent the onset of kidney disease in high-risk individuals, or slow its progression in those already affected. These trials typically involve interventions like lifestyle changes, new medications, dietary modifications, or supplements that may reduce the risk factors associated with kidney disease, like high blood pressure, diabetes, or obesity.
Participants in prevention trials might include people with a family history of kidney disease, those with chronic conditions known to affect kidney function, or individuals with early signs of kidney damage. The goal is to determine whether the intervention can effectively prevent kidney disease or delay its onset or progression, ultimately reducing the incidence and impact of kidney-related health issues.
Treatment trials in clinical research for kidney disease are designed to evaluate the safety and effectiveness of new therapies or interventions aimed at treating the disease or its complications. These trials often focus on medications, surgical procedures, medical devices, or alternative therapies that could improve kidney function, slow disease progression, or alleviate symptoms.
Participants in treatment trials usually include individuals who have been diagnosed with kidney disease, ranging from early-stage chronic kidney disease (CKD) to more advanced stages, including those requiring dialysis or awaiting a kidney transplant. Treatment trials can also involve comparing the new treatment against standard care or a placebo to determine if it offers superior outcomes.
Quality of life (QoL) trials in kidney disease research focus on understanding and improving the overall well-being and daily functioning of patients living with the condition. These trials assess how treatments, interventions, or disease management strategies affect patients' physical, emotional, and social health.
Participants in QoL trials may include individuals at various stages of kidney disease, including those undergoing dialysis, post-transplant patients, or those managing chronic kidney disease (CKD) with medication. The interventions studied might include new therapies, psychological support programs, dietary changes, or exercise regimens.
Participating in a clinical trial for kidney disease gives participants the opportunity to contribute to scientific research that could benefit wider society. While there are risks and considerations involved, kidney disease clinical trial participation can also offer participants a number of benefits.
Access to cutting-edge treatments, close medical monitoring, and the opportunity to contribute to medical research that may benefit future patients are some of the key benefits of participating in a kidney disease clinical trial. Participants will receive treatment at no cost, gain additional support, and may even experience improved health outcomes. Involvement in a trial for kidney disease also allows patients to take an active role in their healthcare decisions.
Participating in a clinical trial for kidney disease carries risks and considerations, such as the possibility of experiencing side effects from the experimental treatment, which may be unknown or more severe than currently available therapies. There's also the chance that the treatment may not be effective, potentially leading to no improvement or worsening of the condition.
Participants may need to commit significant time for frequent medical visits and tests, and they might have to follow strict trial protocols, which can affect their daily life. Additionally, not all trial-related expenses may be covered, and there's the emotional toll of uncertainty about the trial's outcome.
Worried about the risks of participating in a clinical trial? Delve into our comprehensive guide to gain insights into the potential outcomes of participating. Learn about potential risks, benefits, and safety considerations to make an informed decision about your participation in a clinical trial.
Eligibility for participating in a clinical trial for kidney disease varies depending on the specific study, but generally, individuals with a diagnosed kidney condition or those at high risk of developing one may qualify. Trials may target patients at different stages of kidney disease, from early chronic kidney disease (CKD) to those on dialysis or post-transplant.
For most trials, eligibility criteria often include factors like age, gender, medical history, current health status, and previous treatments. Some trials also seek healthy volunteers for comparison.
When participating in a clinical trial for kidney disease, participants can expect to undergo a thorough screening process to ensure they meet the trial’s specific inclusion and exclusion criteria. Following this, a detailed informed consent will be provided where the study’s purpose, procedures, risks, and benefits are explained.
During the trial, participants may receive an experimental treatment, placebo, or standard care, with regular monitoring through medical visits, tests, and assessments to track health and the treatment’s effects.
Enrolling in a clinical trial studying kidney disease through our platform is a straightforward and user-friendly process. Here's how to get started: