Find clinical trials for ALS. Search for oncology clinical trials in different cities and states across the United States.
Sponsor:
Leigh R. Hochberg, MD, PhD.
Location:
Code:
NCT05724173
Conditions
Anarthria
Dysarthria
Tetraplegia
Spinal Cord Injuries
Amyotrophic Lateral Sclerosis
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
BrainGate Neural Interface System
Sponsor:
argenx
Location:
Code:
NCT06441682
Conditions
Amyotrophic Lateral Sclerosis
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
ARGX-119
Placebo
Sponsor:
Biogen
Location:
Code:
NCT04856982
Conditions
Amyotrophic Lateral Sclerosis Associated With a SOD1 Gene Mutation
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
Tofersen
Placebo
Sponsor:
Nova Southeastern University
Location:
Code:
NCT05913882
Conditions
ALS
Respiratory Insufficiency
Dysphagia
Eligibility Criteria
Sex: All
Age: 18 - 70+
Healthy Volunteers: Not accepted
Interventions
Respiratory Muscle Strength Training (LVR+EMST)
Sponsor:
Amydis Inc.
Location:
Code:
NCT05542576
Conditions
Parkinson Disease
Amyotrophic Lateral Sclerosis
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
AMDX2011P
Sponsor:
UniQure Biopharma B.V.
Location:
Code:
NCT06100276
Conditions
Amyotrophic Lateral Sclerosis
Eligibility Criteria
Sex: All
Age: 18+
Healthy Volunteers: Not accepted
Interventions
AMT-162
Sponsor:
Neuralink Corp
Location:
Code:
NCT06700304
Conditions
Tetraplegia/Tetraparesis
Quadriplegia
Quadriplegia/Tetraplegia
Cervical Spinal Cord Injury
Amyotrophic Lateral Sclerosis (ALS)
Eligibility Criteria
Sex: All
Age: 19+
Healthy Volunteers: Not accepted
Interventions
N1 Implant
R1 Robot
Amyotrophic Lateral Sclerosis (ALS) clinical trials are research studies conducted to explore and evaluate new treatments, therapies, and diagnostic tools for ALS, commonly known as Lou Gehrig’s disease. These trials are crucial in the search for effective ways to slow the progression of the disease, manage symptoms, and ultimately find a cure for ALS.
Clinical trials are essential in ALS research as they are the primary method for testing new treatments and interventions. They help in understanding the effectiveness and safety of these treatments in humans. Through these trials, researchers can uncover new insights into the disease, leading to improved care, symptom management, and potentially life-extending therapies for those affected by ALS.
These trials can vary based on the type of intervention being studied, the phase of development, and the specific objectives of the trial. Some common types of ALS clinical trials are:
These trials focus on finding new ways to alleviate the symptoms associated with ALS, such as muscle weakness, difficulty speaking, and respiratory issues. They test new medications, physical therapies, and other interventions aimed at improving the quality of life for individuals living with ALS.
Disease-modifying trials aim to discover treatments that can alter the course of ALS. These include studies on drugs that could potentially slow down or halt the progression of the disease, providing hope for extending the lives of ALS patients.
Supportive care and rehabilitation trials test interventions designed to support the overall well-being of ALS patients. They include studies on rehabilitation techniques, adaptive equipment, and strategies to assist with daily activities, focusing on maintaining independence and enhancing quality of life.
Emerging therapy trials explore the potential of groundbreaking treatments such as gene therapy, stem cell treatment, and innovative medical devices. These studies represent the cutting-edge of ALS research, seeking novel ways to tackle the disease.
Innovations in ALS treatment through clinical trials are making significant progress in several key areas. One major area is the development of new medications and drug therapies. These trials involve detailed testing of new drugs to see how they affect ALS progression and symptoms.
Another area of research is neuroprotective strategies, which aim to protect nerve cells from damage and slow down the disease's progression, using various medications and supplements.
Additionally, clinical trials are looking into the effects of diet and lifestyle changes on ALS. These studies are testing different dietary supplements and lifestyle adjustments to see if they can help manage ALS and improve patients' quality of life.
Individuals diagnosed with ALS are typically eligible to participate in clinical trials. Each trial has specific inclusion criteria, which might include the stage of the disease, overall health status, and previous treatment history. Some trials might also be open to individuals without ALS for observational or preventative studies, or to compare health outcomes.
Participating in an ALS clinical trial typically involves a pre-screening process, informed consent, and baseline health assessments. Participants are often randomized into treatment or control groups and undergo the trial's therapy while being closely monitored for effectiveness and side effects. Regular medical check-ups and tests are conducted throughout the trial to track the disease's progression. Participants are required to adhere to specific trial protocols and have the right to withdraw at any time.
Unsure about participating in a clinical trial? Dive into our comprehensive guide to learn about the process, benefits, and potential impact of your involvement. Get the facts you need to make an informed decision today!
Enrolling in a clinical trial for ALS through our platform is a straightforward and user-friendly process. Here's how to get started: