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ALS Clinical Trials

Find clinical trials for ALS. Search for oncology clinical trials in different cities and states across the United States.

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1

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

Recruiting

Sponsor:

Leigh R. Hochberg, MD, PhD.

Location:

Stanford, Boston

Code:

NCT05724173

Conditions

Anarthria

Dysarthria

Tetraplegia

Spinal Cord Injuries

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

BrainGate Neural Interface System

A Safety and Efficacy Study of ARGX-119 in Adult Patients with Amyotrophic Lateral Sclerosis (ALS)

Recruiting
PHASE2

Sponsor:

argenx

Location:

Montreal

Code:

NCT06441682

Conditions

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

ARGX-119

Placebo

A Study of BIIB067 (Tofersen) Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation

Recruiting
PHASE3

Sponsor:

Biogen

Location:

Scottsdale, La Jolla, San Francisco, Fort Lauderdaleshow 11 more

Code:

NCT04856982

Conditions

Amyotrophic Lateral Sclerosis Associated With a SOD1 Gene Mutation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Tofersen

Placebo

Combined Respiratory Training in Persons with ALS

Recruiting

Sponsor:

Nova Southeastern University

Location:

Fort Lauderdale

Code:

NCT05913882

Conditions

ALS

Respiratory Insufficiency

Dysphagia

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Respiratory Muscle Strength Training (LVR+EMST)

Amyotrophic Lateral Sclerosis (ALS) Families Project

Recruiting

Sponsor:

Columbia University

Location:

New York

Code:

NCT03865420

Conditions

ALS

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

AMDX-2011P Retinal Tracer in Subjects With Neurodegenerative Diseases Associated With Amyloidogenic Proteinopathy

Recruiting
PHASE1
PHASE2

Sponsor:

Amydis Inc.

Location:

Newport Beach, Pasadena

Code:

NCT05542576

Conditions

Parkinson Disease

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

AMDX2011P

CNS10-NPC-GDNF Delivered to the Motor Cortex for ALS

Recruiting
PHASE1

Sponsor:

Cedars-Sinai Medical Center

Location:

Los Angeles

Code:

NCT05306457

Conditions

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

CNS10-NPC-GDNF

Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants with SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)

Recruiting
PHASE1
PHASE2

Sponsor:

UniQure Biopharma B.V.

Location:

Irvine, San Francisco, Jacksonville, Atlantashow 6 more

Code:

NCT06100276

Conditions

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

AMT-162

Mitochondrial Capacity Boost in ALS (MICABO-ALS) Trial

Recruiting
PHASE2

Sponsor:

Dallas VA Medical Center

Location:

Dallas

Code:

NCT04244630

Conditions

Amyotrophic Lateral Sclerosis (ALS)

Eligibility Criteria

Sex: All

Age: 21 - 70+

Healthy Volunteers: Not accepted

Interventions

Antioxidants

Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices

Recruiting

Sponsor:

Neuralink Corp

Location:

Toronto

Code:

NCT06700304

Conditions

Tetraplegia/Tetraparesis

Quadriplegia

Quadriplegia/Tetraplegia

Cervical Spinal Cord Injury

Amyotrophic Lateral Sclerosis (ALS)

Eligibility Criteria

Sex: All

Age: 19+

Healthy Volunteers: Not accepted

Interventions

N1 Implant

R1 Robot

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