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ALS Clinical Trials

Find clinical trials for ALS. Search for ALS clinical trials in different cities and states across the United States.

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Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

Recruiting

Sponsor:

Leigh R. Hochberg, MD, PhD.

Location:

Stanford, Boston

Code:

NCT05724173

Conditions

Anarthria

Dysarthria

Tetraplegia

Spinal Cord Injuries

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

BrainGate Neural Interface System

A Study of BIIB067 (Tofersen) Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation

Recruiting
PHASE3

Sponsor:

Biogen

Location:

Scottsdale, La Jolla, San Francisco, Fort Lauderdaleshow 11 more

Code:

NCT04856982

Conditions

Amyotrophic Lateral Sclerosis Associated With a SOD1 Gene Mutation

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

Tofersen

Placebo

Amyotrophic Lateral Sclerosis (ALS) Families Project

Recruiting

Sponsor:

Columbia University

Location:

New York

Code:

NCT03865420

Conditions

ALS

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

A Safety and Efficacy Study of ARGX-119 in Adult Patients with Amyotrophic Lateral Sclerosis (ALS)

Recruiting
PHASE2

Sponsor:

argenx

Location:

Montreal, Edmonton

Code:

NCT06441682

Conditions

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

ARGX-119

Placebo

Combined Respiratory Training in Persons with ALS

Recruiting

Sponsor:

Nova Southeastern University

Location:

Fort Lauderdale

Code:

NCT05913882

Conditions

ALS

Respiratory Insufficiency

Dysphagia

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Respiratory Muscle Strength Training (LVR+EMST)

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

Recruiting
PHASE3

Sponsor:

AB Science

Location:

Birmingham, Los Angeles, Lexington, Baltimoreshow 2 more

Code:

NCT03127267

Conditions

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Masitinib (6.0)

Riluzole

Placebo

Masitinib (4.5)

CNS10-NPC-GDNF Delivered to the Motor Cortex for ALS

Recruiting
PHASE1

Sponsor:

Cedars-Sinai Medical Center

Location:

Los Angeles

Code:

NCT05306457

Conditions

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18+

Healthy Volunteers: Not accepted

Interventions

CNS10-NPC-GDNF

A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALS

Recruiting
PHASE2

Sponsor:

McGill University

Location:

Montreal

Code:

NCT06249867

Conditions

Amyotrophic Lateral Sclerosis

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

Interventions

Darifenacin 7.5 MG Extended Release Oral Tablet

Placebo

Precise Robotically IMplanted Brain-Computer InterfacE

Recruiting

Sponsor:

Neuralink Corp

Location:

Phoenix

Code:

NCT06429735

Conditions

Tetraplegia/Tetraparesis

Quadriplegia

Cervical Spinal Cord Injury

Amyotrophic Lateral Sclerosis

Quadriplegia/Tetraplegia

Eligibility Criteria

Sex: All

Age: 22 - 70+

Healthy Volunteers: Not accepted

Interventions

N1 Implant

R1 Robot

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Recruiting

Sponsor:

National Institute of Neurological Disorders and Stroke (NINDS)

Location:

Bethesda

Code:

NCT03225144

Conditions

Frontotemporal Dementia

Amyotrophic Lateral Sclerosis

Progressive Supranuclear Palsy

Eligibility Criteria

Sex: All

Age: 18 - 70+

Healthy Volunteers: Not accepted

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